ID   LSRB_YERE8              Reviewed;         344 AA.
AC   A1JJ52;
DT   14-OCT-2008, integrated into UniProtKB/Swiss-Prot.
DT   06-FEB-2007, sequence version 1.
DT   03-AUG-2022, entry version 69.
DE   RecName: Full=Autoinducer 2-binding protein LsrB;
DE            Short=AI-2-binding protein LsrB;
DE   Flags: Precursor;
GN   Name=lsrB; OrderedLocusNames=YE0525;
OS   Yersinia enterocolitica serotype O:8 / biotype 1B (strain NCTC 13174 /
OS   8081).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Yersiniaceae; Yersinia.
OX   NCBI_TaxID=393305;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NCTC 13174 / 8081;
RX   PubMed=17173484; DOI=10.1371/journal.pgen.0020206;
RA   Thomson N.R., Howard S., Wren B.W., Holden M.T.G., Crossman L.,
RA   Challis G.L., Churcher C., Mungall K., Brooks K., Chillingworth T.,
RA   Feltwell T., Abdellah Z., Hauser H., Jagels K., Maddison M., Moule S.,
RA   Sanders M., Whitehead S., Quail M.A., Dougan G., Parkhill J.,
RA   Prentice M.B.;
RT   "The complete genome sequence and comparative genome analysis of the high
RT   pathogenicity Yersinia enterocolitica strain 8081.";
RL   PLoS Genet. 2:2039-2051(2006).
CC   -!- FUNCTION: Part of the ABC transporter complex LsrABCD involved in
CC       autoinducer 2 (AI-2) import. Binds AI-2 and delivers it to the LsrC and
CC       LsrD permeases (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: The complex is composed of two ATP-binding proteins (LsrA),
CC       two transmembrane proteins (LsrC and LsrD) and a solute-binding protein
CC       (LsrB). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the bacterial solute-binding protein 2 family.
CC       {ECO:0000305}.
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DR   EMBL; AM286415; CAL10643.1; -; Genomic_DNA.
DR   RefSeq; WP_005175219.1; NC_008800.1.
DR   RefSeq; YP_001004885.1; NC_008800.1.
DR   AlphaFoldDB; A1JJ52; -.
DR   SMR; A1JJ52; -.
DR   STRING; 393305.YE0525; -.
DR   EnsemblBacteria; CAL10643; CAL10643; YE0525.
DR   KEGG; yen:YE0525; -.
DR   PATRIC; fig|393305.7.peg.615; -.
DR   eggNOG; COG1879; Bacteria.
DR   HOGENOM; CLU_037628_3_0_6; -.
DR   OMA; KQVNNPY; -.
DR   Proteomes; UP000000642; Chromosome.
DR   GO; GO:0043190; C:ATP-binding cassette (ABC) transporter complex; IEA:InterPro.
DR   GO; GO:0030288; C:outer membrane-bounded periplasmic space; IEA:UniProt.
DR   CDD; cd20003; PBP1_LsrB_Quorum_Sensing; 1.
DR   InterPro; IPR030159; LsrB.
DR   InterPro; IPR028082; Peripla_BP_I.
DR   InterPro; IPR025997; SBP_2_dom.
DR   PANTHER; PTHR46847:SF4; PTHR46847:SF4; 1.
DR   Pfam; PF13407; Peripla_BP_4; 1.
DR   SUPFAM; SSF53822; SSF53822; 1.
PE   3: Inferred from homology;
KW   Periplasm; Signal.
FT   SIGNAL          1..30
FT                   /evidence="ECO:0000255"
FT   CHAIN           31..344
FT                   /note="Autoinducer 2-binding protein LsrB"
FT                   /id="PRO_5000200894"
SQ   SEQUENCE   344 AA;  37174 MW;  92AE07066DFA0106 CRC64;
     MKTPRLKKLA LVCALGFACI TFSAINAVQA AERIAFIPKL VGVGFFTSGG KGAVDAGKEL
     GVDVTYDGPT EPSVSGQVQL INNFVNQGYN AIVVSAVSPD GLCPALKRAM QRGVKILTWD
     SDTKPECRSV YINQGTPNQL GSMLVDMAAN QVKKDKAKVA FFYSSPTVTD QNQWVNEAKK
     KIQQEHPGWE IVTTQFGYND ATKSLQTAEG ILKAYSDLDA IIAPDANALP AAAQAAENLK
     RDNVAIVGFS TPNVMRPYVE RGTVKEFGLW DVVNQGKISV YVANEMLKKG DLNVGDKIDI
     PNIGVVEVAP NSVQGYDHEA KGSGIVLLPQ RVIFTKENID KYDF