LSRB_YERPA
ID LSRB_YERPA Reviewed; 339 AA.
AC Q1C135;
DT 14-OCT-2008, integrated into UniProtKB/Swiss-Prot.
DT 11-JUL-2006, sequence version 1.
DT 03-AUG-2022, entry version 71.
DE RecName: Full=Autoinducer 2-binding protein LsrB;
DE Short=AI-2-binding protein LsrB;
DE Flags: Precursor;
GN Name=lsrB; OrderedLocusNames=YPA_3876;
OS Yersinia pestis bv. Antiqua (strain Antiqua).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Yersiniaceae; Yersinia.
OX NCBI_TaxID=360102;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Antiqua;
RX PubMed=16740952; DOI=10.1128/jb.00124-06;
RA Chain P.S.G., Hu P., Malfatti S.A., Radnedge L., Larimer F., Vergez L.M.,
RA Worsham P., Chu M.C., Andersen G.L.;
RT "Complete genome sequence of Yersinia pestis strains Antiqua and Nepal516:
RT evidence of gene reduction in an emerging pathogen.";
RL J. Bacteriol. 188:4453-4463(2006).
CC -!- FUNCTION: Part of the ABC transporter complex LsrABCD involved in
CC autoinducer 2 (AI-2) import. Binds AI-2 and delivers it to the LsrC and
CC LsrD permeases (By similarity). {ECO:0000250}.
CC -!- SUBUNIT: The complex is composed of two ATP-binding proteins (LsrA),
CC two transmembrane proteins (LsrC and LsrD) and a solute-binding protein
CC (LsrB). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the bacterial solute-binding protein 2 family.
CC {ECO:0000305}.
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DR EMBL; CP000308; ABG15837.1; -; Genomic_DNA.
DR RefSeq; WP_002209189.1; NZ_CP009906.1.
DR AlphaFoldDB; Q1C135; -.
DR SMR; Q1C135; -.
DR EnsemblBacteria; ABG15837; ABG15837; YPA_3876.
DR GeneID; 57974201; -.
DR KEGG; ypa:YPA_3876; -.
DR OMA; KQVNNPY; -.
DR Proteomes; UP000001971; Chromosome.
DR GO; GO:0043190; C:ATP-binding cassette (ABC) transporter complex; IEA:InterPro.
DR GO; GO:0030288; C:outer membrane-bounded periplasmic space; IEA:UniProt.
DR CDD; cd20003; PBP1_LsrB_Quorum_Sensing; 1.
DR InterPro; IPR030159; LsrB.
DR InterPro; IPR028082; Peripla_BP_I.
DR InterPro; IPR025997; SBP_2_dom.
DR PANTHER; PTHR46847:SF4; PTHR46847:SF4; 1.
DR Pfam; PF13407; Peripla_BP_4; 1.
DR SUPFAM; SSF53822; SSF53822; 1.
PE 3: Inferred from homology;
KW Periplasm; Signal.
FT SIGNAL 1..25
FT /evidence="ECO:0000255"
FT CHAIN 26..339
FT /note="Autoinducer 2-binding protein LsrB"
FT /id="PRO_5000116340"
SQ SEQUENCE 339 AA; 36708 MW; 43DF0D22B6239FD3 CRC64;
MRTQRLKKLA LVCALGFACI TTAQAAERIA FIPKLVGVGF FTSGGKGAVD AGKALGVDVT
YDGPTEPSVS GQVQLINNFV NQGYNAIVVS AVSPDGLCPA LKRAMQRGVK ILTWDSDTKP
ECRSVYINQG TPNQLGSMLV DMAANQVKKE QAKVAFFYSS PTVTDQNQWV NEAKKKIQQE
HPGWEIVTTQ FGYNDATKSL QTAEGILKAY ADLDAIIAPD ANALPAAAQA AENLKRANVA
IVGFSTPNVM RPYVERGTVK EFGLWDVVNQ GKISVYVANE MLKKGDLNVG DKIDIPNIGV
VEVSPNRVQG YDYEAKGNGI VLLPQRVIFT KENISKYDF