ID   LSRB_YERPP              Reviewed;         339 AA.
AC   A4TQL8;
DT   14-OCT-2008, integrated into UniProtKB/Swiss-Prot.
DT   15-MAY-2007, sequence version 1.
DT   03-AUG-2022, entry version 65.
DE   RecName: Full=Autoinducer 2-binding protein LsrB;
DE            Short=AI-2-binding protein LsrB;
DE   Flags: Precursor;
GN   Name=lsrB; OrderedLocusNames=YPDSF_3222;
OS   Yersinia pestis (strain Pestoides F).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Yersiniaceae; Yersinia.
OX   NCBI_TaxID=386656;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Pestoides F;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA   Di Bartolo G., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J.,
RA   Larimer F., Land M., Hauser L., Worsham P., Chu M., Bearden S., Garcia E.,
RA   Richardson P.;
RT   "Complete sequence of chromosome of Yersinia pestis Pestoides F.";
RL   Submitted (FEB-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Part of the ABC transporter complex LsrABCD involved in
CC       autoinducer 2 (AI-2) import. Binds AI-2 and delivers it to the LsrC and
CC       LsrD permeases (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: The complex is composed of two ATP-binding proteins (LsrA),
CC       two transmembrane proteins (LsrC and LsrD) and a solute-binding protein
CC       (LsrB). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the bacterial solute-binding protein 2 family.
CC       {ECO:0000305}.
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DR   EMBL; CP000668; ABP41580.1; -; Genomic_DNA.
DR   RefSeq; WP_002209189.1; NZ_CP009715.1.
DR   AlphaFoldDB; A4TQL8; -.
DR   SMR; A4TQL8; -.
DR   GeneID; 57974201; -.
DR   KEGG; ypp:YPDSF_3222; -.
DR   PATRIC; fig|386656.14.peg.1122; -.
DR   OMA; KQVNNPY; -.
DR   GO; GO:0043190; C:ATP-binding cassette (ABC) transporter complex; IEA:InterPro.
DR   GO; GO:0030288; C:outer membrane-bounded periplasmic space; IEA:UniProt.
DR   CDD; cd20003; PBP1_LsrB_Quorum_Sensing; 1.
DR   InterPro; IPR030159; LsrB.
DR   InterPro; IPR028082; Peripla_BP_I.
DR   InterPro; IPR025997; SBP_2_dom.
DR   PANTHER; PTHR46847:SF4; PTHR46847:SF4; 1.
DR   Pfam; PF13407; Peripla_BP_4; 1.
DR   SUPFAM; SSF53822; SSF53822; 1.
PE   3: Inferred from homology;
KW   Periplasm; Signal.
FT   SIGNAL          1..25
FT                   /evidence="ECO:0000255"
FT   CHAIN           26..339
FT                   /note="Autoinducer 2-binding protein LsrB"
FT                   /id="PRO_5000237032"
SQ   SEQUENCE   339 AA;  36708 MW;  43DF0D22B6239FD3 CRC64;
     MRTQRLKKLA LVCALGFACI TTAQAAERIA FIPKLVGVGF FTSGGKGAVD AGKALGVDVT
     YDGPTEPSVS GQVQLINNFV NQGYNAIVVS AVSPDGLCPA LKRAMQRGVK ILTWDSDTKP
     ECRSVYINQG TPNQLGSMLV DMAANQVKKE QAKVAFFYSS PTVTDQNQWV NEAKKKIQQE
     HPGWEIVTTQ FGYNDATKSL QTAEGILKAY ADLDAIIAPD ANALPAAAQA AENLKRANVA
     IVGFSTPNVM RPYVERGTVK EFGLWDVVNQ GKISVYVANE MLKKGDLNVG DKIDIPNIGV
     VEVSPNRVQG YDYEAKGNGI VLLPQRVIFT KENISKYDF