LSRB_YERPS
ID LSRB_YERPS Reviewed; 339 AA.
AC Q66EZ2;
DT 14-OCT-2008, integrated into UniProtKB/Swiss-Prot.
DT 11-OCT-2004, sequence version 1.
DT 03-AUG-2022, entry version 76.
DE RecName: Full=Autoinducer 2-binding protein LsrB;
DE Short=AI-2-binding protein LsrB;
DE Flags: Precursor;
GN Name=lsrB; OrderedLocusNames=YPTB0549;
OS Yersinia pseudotuberculosis serotype I (strain IP32953).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Yersiniaceae; Yersinia.
OX NCBI_TaxID=273123;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IP32953;
RX PubMed=15358858; DOI=10.1073/pnas.0404012101;
RA Chain P.S.G., Carniel E., Larimer F.W., Lamerdin J., Stoutland P.O.,
RA Regala W.M., Georgescu A.M., Vergez L.M., Land M.L., Motin V.L.,
RA Brubaker R.R., Fowler J., Hinnebusch J., Marceau M., Medigue C.,
RA Simonet M., Chenal-Francisque V., Souza B., Dacheux D., Elliott J.M.,
RA Derbise A., Hauser L.J., Garcia E.;
RT "Insights into the evolution of Yersinia pestis through whole-genome
RT comparison with Yersinia pseudotuberculosis.";
RL Proc. Natl. Acad. Sci. U.S.A. 101:13826-13831(2004).
CC -!- FUNCTION: Part of the ABC transporter complex LsrABCD involved in
CC autoinducer 2 (AI-2) import. Binds AI-2 and delivers it to the LsrC and
CC LsrD permeases (By similarity). {ECO:0000250}.
CC -!- SUBUNIT: The complex is composed of two ATP-binding proteins (LsrA),
CC two transmembrane proteins (LsrC and LsrD) and a solute-binding protein
CC (LsrB). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the bacterial solute-binding protein 2 family.
CC {ECO:0000305}.
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DR EMBL; BX936398; CAH19789.1; -; Genomic_DNA.
DR RefSeq; WP_011191662.1; NZ_CP009712.1.
DR AlphaFoldDB; Q66EZ2; -.
DR SMR; Q66EZ2; -.
DR EnsemblBacteria; CAH19789; CAH19789; YPTB0549.
DR GeneID; 66843032; -.
DR KEGG; ypo:BZ17_2010; -.
DR KEGG; yps:YPTB0549; -.
DR PATRIC; fig|273123.14.peg.2136; -.
DR OMA; KQVNNPY; -.
DR Proteomes; UP000001011; Chromosome.
DR GO; GO:0043190; C:ATP-binding cassette (ABC) transporter complex; IEA:InterPro.
DR GO; GO:0030288; C:outer membrane-bounded periplasmic space; IEA:UniProt.
DR CDD; cd20003; PBP1_LsrB_Quorum_Sensing; 1.
DR InterPro; IPR030159; LsrB.
DR InterPro; IPR028082; Peripla_BP_I.
DR InterPro; IPR025997; SBP_2_dom.
DR PANTHER; PTHR46847:SF4; PTHR46847:SF4; 1.
DR Pfam; PF13407; Peripla_BP_4; 1.
DR SUPFAM; SSF53822; SSF53822; 1.
PE 3: Inferred from homology;
KW Periplasm; Signal.
FT SIGNAL 1..25
FT /evidence="ECO:0000255"
FT CHAIN 26..339
FT /note="Autoinducer 2-binding protein LsrB"
FT /id="PRO_5000098424"
SQ SEQUENCE 339 AA; 36694 MW; 41E10882B6239A73 CRC64;
MRTQRLKKLA LVCALGFACI TTAQAAERIA FIPKLVGVGF FTSGGKGAVD AGKALGVDVT
YDGPTEPSVS GQVQLINNFV NQGYNAIVVS AVSPDGLCPA LKRAMQRGVK ILTWDSDTKP
ECRSVYINQG TPNQLGSMLV DMAANQVKKE QAKVAFFYSS PTVTDQNQWV NEAKKKIQQE
HPGWEIVTTQ FGYNDATKSL QTAEGILKAY GDLDAIIAPD ANALPAAAQA AENLKRANVA
IVGFSTPNVM RPYVERGTVK EFGLWDVVNQ GKISVYVANE MLKKGDLNVG DKIDIPNIGV
VEVSPNRVQG YDYEAKGNGI VLLPQRVIFT KENISKYDF