ID   LSRC_SALPA              Reviewed;         347 AA.
AC   Q5PJE6;
DT   14-OCT-2008, integrated into UniProtKB/Swiss-Prot.
DT   04-JAN-2005, sequence version 1.
DT   25-MAY-2022, entry version 72.
DE   RecName: Full=Autoinducer 2 import system permease protein LsrC;
DE            Short=AI-2 import system permease protein LsrC;
GN   Name=lsrC; OrderedLocusNames=SPA3918;
OS   Salmonella paratyphi A (strain ATCC 9150 / SARB42).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=295319;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 9150 / SARB42;
RX   PubMed=15531882; DOI=10.1038/ng1470;
RA   McClelland M., Sanderson K.E., Clifton S.W., Latreille P., Porwollik S.,
RA   Sabo A., Meyer R., Bieri T., Ozersky P., McLellan M., Harkins C.R.,
RA   Wang C., Nguyen C., Berghoff A., Elliott G., Kohlberg S., Strong C., Du F.,
RA   Carter J., Kremizki C., Layman D., Leonard S., Sun H., Fulton L., Nash W.,
RA   Miner T., Minx P., Delehaunty K., Fronick C., Magrini V., Nhan M.,
RA   Warren W., Florea L., Spieth J., Wilson R.K.;
RT   "Comparison of genome degradation in Paratyphi A and Typhi, human-
RT   restricted serovars of Salmonella enterica that cause typhoid.";
RL   Nat. Genet. 36:1268-1274(2004).
CC   -!- FUNCTION: Part of the ABC transporter complex LsrABCD involved in
CC       autoinducer 2 (AI-2) import. Probably responsible for the translocation
CC       of the substrate across the membrane (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: The complex is composed of two ATP-binding proteins (LsrA),
CC       two transmembrane proteins (LsrC and LsrD) and a solute-binding protein
CC       (LsrB). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000250}; Multi-pass
CC       membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the binding-protein-dependent transport system
CC       permease family. AraH/RbsC subfamily. {ECO:0000305}.
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DR   EMBL; CP000026; AAV79683.1; -; Genomic_DNA.
DR   RefSeq; WP_000911134.1; NC_006511.1.
DR   AlphaFoldDB; Q5PJE6; -.
DR   EnsemblBacteria; AAV79683; AAV79683; SPA3918.
DR   KEGG; spt:SPA3918; -.
DR   HOGENOM; CLU_028880_0_1_6; -.
DR   OMA; KRMLKMH; -.
DR   Proteomes; UP000008185; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   InterPro; IPR001851; ABC_transp_permease.
DR   Pfam; PF02653; BPD_transp_2; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..347
FT                   /note="Autoinducer 2 import system permease protein LsrC"
FT                   /id="PRO_0000351347"
FT   TRANSMEM        14..34
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        39..59
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        72..92
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        93..113
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        115..135
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        155..175
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        213..233
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        249..269
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        284..304
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   347 AA;  36926 MW;  509EDD0083DBAE48 CRC64;
     MLKFIQNNRE ATALLAIVCL FVFPGALDSQ YLSVQTLTMV FSSAQILMLL AIGATMVMLT
     RNIDVSVGST TGMCAVLLGV MLNAGYSLPV ACLATLILGI VAGFFNGVLV AWLKIPAIVA
     TLGTLGLYRG IMLLWTGGKW IEGLPAGLKQ LSAPVFLGIS AIGWFTLVLA LLMAWLLAKT
     AFGRNFYATG DNLQGARQLG VRTEMVRIMA FSLNGGMAAL AGIVFASQIG FIPNQTGTGL
     EMKAIAACVL GGISLLGGSG TVIGAILGAY FLTQIDSVLV LLRIPAWWND FIAGLVLLGV
     LVFDGRLRCA LQRNLRRQKY ARFISPPTPL QTEAKTHAQQ NKNKEVA