LSRC_SALPB
ID LSRC_SALPB Reviewed; 346 AA.
AC A9MZG2;
DT 14-OCT-2008, integrated into UniProtKB/Swiss-Prot.
DT 05-FEB-2008, sequence version 1.
DT 25-MAY-2022, entry version 61.
DE RecName: Full=Autoinducer 2 import system permease protein LsrC;
DE Short=AI-2 import system permease protein LsrC;
GN Name=lsrC; OrderedLocusNames=SPAB_05049;
OS Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Salmonella.
OX NCBI_TaxID=1016998;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-1250 / SPB7;
RG The Salmonella enterica serovar Paratyphi B Genome Sequencing Project;
RA McClelland M., Sanderson E.K., Porwollik S., Spieth J., Clifton W.S.,
RA Fulton R., Cordes M., Wollam A., Shah N., Pepin K., Bhonagiri V., Nash W.,
RA Johnson M., Thiruvilangam P., Wilson R.;
RL Submitted (NOV-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Part of the ABC transporter complex LsrABCD involved in
CC autoinducer 2 (AI-2) import. Probably responsible for the translocation
CC of the substrate across the membrane (By similarity). {ECO:0000250}.
CC -!- SUBUNIT: The complex is composed of two ATP-binding proteins (LsrA),
CC two transmembrane proteins (LsrC and LsrD) and a solute-binding protein
CC (LsrB). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000250}; Multi-pass
CC membrane protein {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the binding-protein-dependent transport system
CC permease family. AraH/RbsC subfamily. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP000886; ABX70340.1; -; Genomic_DNA.
DR AlphaFoldDB; A9MZG2; -.
DR KEGG; spq:SPAB_05049; -.
DR PATRIC; fig|1016998.12.peg.4739; -.
DR HOGENOM; CLU_028880_0_1_6; -.
DR OMA; KRMLKMH; -.
DR Proteomes; UP000008556; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR InterPro; IPR001851; ABC_transp_permease.
DR Pfam; PF02653; BPD_transp_2; 1.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Membrane; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..346
FT /note="Autoinducer 2 import system permease protein LsrC"
FT /id="PRO_0000351348"
FT TRANSMEM 13..33
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 38..58
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 71..91
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 92..112
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 114..134
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 154..174
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 212..232
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 248..268
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 283..303
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 346 AA; 36783 MW; 19352F84B1CD8877 CRC64;
MKFIQNNREA TALLAIVCLF VFPGALDSQY LSVQTLTMVF SSAQILMLLA IGATMVMLTR
NIDVSVGSTT GMCAVLLGVM LNAGYSLPVA CLATLILGIV AGFFNGVLVA WLKIPAIVAT
LGTLGLYRGI MLLWTGGKWI EGLPAGLKQL SAPVFLGISA IGWFTLVLAL LMAWLLAKTA
FGRNFYATGD NLQGARQLGV RTEMVRIMAF SLNGGMAALA GIVFASQIGF IPNQTGTGLE
MKAIAACVLG GISLLGGSGT VIGAILGAYF LTQIDSVLVL LRIPAWWNDF IAGLVLLGVL
VFDGRLRCAL QRNLRRQKYA RFISPPTPLQ AEAKTHAQQN KNKEVA