LSRC_YERPA
ID LSRC_YERPA Reviewed; 351 AA.
AC Q1C137;
DT 14-OCT-2008, integrated into UniProtKB/Swiss-Prot.
DT 11-JUL-2006, sequence version 1.
DT 25-MAY-2022, entry version 75.
DE RecName: Full=Autoinducer 2 import system permease protein LsrC;
DE Short=AI-2 import system permease protein LsrC;
GN Name=lsrC; OrderedLocusNames=YPA_3874;
OS Yersinia pestis bv. Antiqua (strain Antiqua).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Yersiniaceae; Yersinia.
OX NCBI_TaxID=360102;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Antiqua;
RX PubMed=16740952; DOI=10.1128/jb.00124-06;
RA Chain P.S.G., Hu P., Malfatti S.A., Radnedge L., Larimer F., Vergez L.M.,
RA Worsham P., Chu M.C., Andersen G.L.;
RT "Complete genome sequence of Yersinia pestis strains Antiqua and Nepal516:
RT evidence of gene reduction in an emerging pathogen.";
RL J. Bacteriol. 188:4453-4463(2006).
CC -!- FUNCTION: Part of the ABC transporter complex LsrABCD involved in
CC autoinducer 2 (AI-2) import. Probably responsible for the translocation
CC of the substrate across the membrane (By similarity). {ECO:0000250}.
CC -!- SUBUNIT: The complex is composed of two ATP-binding proteins (LsrA),
CC two transmembrane proteins (LsrC and LsrD) and a solute-binding protein
CC (LsrB). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000250}; Multi-pass
CC membrane protein {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the binding-protein-dependent transport system
CC permease family. AraH/RbsC subfamily. {ECO:0000305}.
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DR EMBL; CP000308; ABG15835.1; -; Genomic_DNA.
DR RefSeq; WP_002209191.1; NZ_CP009906.1.
DR AlphaFoldDB; Q1C137; -.
DR EnsemblBacteria; ABG15835; ABG15835; YPA_3874.
DR GeneID; 57974199; -.
DR KEGG; ypa:YPA_3874; -.
DR OMA; KRMLKMH; -.
DR Proteomes; UP000001971; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR InterPro; IPR001851; ABC_transp_permease.
DR Pfam; PF02653; BPD_transp_2; 1.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Membrane; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..351
FT /note="Autoinducer 2 import system permease protein LsrC"
FT /id="PRO_0000351357"
FT TRANSMEM 14..34
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 39..59
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 70..90
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 93..113
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 115..135
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 155..175
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 213..233
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 252..272
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 284..304
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 351 AA; 37247 MW; D3049DFF47BDF1F5 CRC64;
MLKFIQNNRE GTALLAILTL FALLGIIDRN YFSLQTFTMI FSSAQILILL AIGATLVMLT
RNIDVSVGSI TGLCAVTVGM ALNAGFGLAA SCLFALLVGM VAGFFNGILV TWLRIPAIVA
TLGTLGLYRG LMLLLTGGKW IEGLPADLKS LSTPILFSIS PIGWLTMLLI LAMAWLLGKT
AFGRSFYATG DNLQGARQLG VRTDSLRIFA FSMNGVMAAL AGIVFASQIG FIPNQTGNGL
EMKAIAACVL GGISLLGGTG TIIGAILGAF LLTQIDSVLV LLRLPAWWND FIAGLVLLGV
LVFDGRLRCA VERNIRQQKY ARFTAQAIIS DKKPTVSDNN PAASNKKKAA L