LSRC_YERPS
ID LSRC_YERPS Reviewed; 351 AA.
AC Q66EZ0;
DT 14-OCT-2008, integrated into UniProtKB/Swiss-Prot.
DT 11-OCT-2004, sequence version 1.
DT 25-MAY-2022, entry version 81.
DE RecName: Full=Autoinducer 2 import system permease protein LsrC;
DE Short=AI-2 import system permease protein LsrC;
GN Name=lsrC; OrderedLocusNames=YPTB0551;
OS Yersinia pseudotuberculosis serotype I (strain IP32953).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Yersiniaceae; Yersinia.
OX NCBI_TaxID=273123;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IP32953;
RX PubMed=15358858; DOI=10.1073/pnas.0404012101;
RA Chain P.S.G., Carniel E., Larimer F.W., Lamerdin J., Stoutland P.O.,
RA Regala W.M., Georgescu A.M., Vergez L.M., Land M.L., Motin V.L.,
RA Brubaker R.R., Fowler J., Hinnebusch J., Marceau M., Medigue C.,
RA Simonet M., Chenal-Francisque V., Souza B., Dacheux D., Elliott J.M.,
RA Derbise A., Hauser L.J., Garcia E.;
RT "Insights into the evolution of Yersinia pestis through whole-genome
RT comparison with Yersinia pseudotuberculosis.";
RL Proc. Natl. Acad. Sci. U.S.A. 101:13826-13831(2004).
CC -!- FUNCTION: Part of the ABC transporter complex LsrABCD involved in
CC autoinducer 2 (AI-2) import. Probably responsible for the translocation
CC of the substrate across the membrane (By similarity). {ECO:0000250}.
CC -!- SUBUNIT: The complex is composed of two ATP-binding proteins (LsrA),
CC two transmembrane proteins (LsrC and LsrD) and a solute-binding protein
CC (LsrB). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000250}; Multi-pass
CC membrane protein {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the binding-protein-dependent transport system
CC permease family. AraH/RbsC subfamily. {ECO:0000305}.
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DR EMBL; BX936398; CAH19791.1; -; Genomic_DNA.
DR RefSeq; WP_011191664.1; NZ_CP009712.1.
DR AlphaFoldDB; Q66EZ0; -.
DR EnsemblBacteria; CAH19791; CAH19791; YPTB0551.
DR GeneID; 66843030; -.
DR KEGG; ypo:BZ17_2008; -.
DR KEGG; yps:YPTB0551; -.
DR PATRIC; fig|273123.14.peg.2134; -.
DR OMA; KRMLKMH; -.
DR Proteomes; UP000001011; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR InterPro; IPR001851; ABC_transp_permease.
DR Pfam; PF02653; BPD_transp_2; 1.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Membrane; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..351
FT /note="Autoinducer 2 import system permease protein LsrC"
FT /id="PRO_0000351359"
FT TRANSMEM 14..34
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 39..59
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 70..90
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 93..113
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 115..135
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 155..175
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 213..233
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 252..272
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 284..304
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 351 AA; 37277 MW; C58FD5F0F514482E CRC64;
MLKFIQNNRE GTALLAILTL FALLGIIDRN YFSLQTFTMI FSSAQILILL AIGATLVMLT
RNIDVSVGSI TGLCAVTVGM ALNAGFGLVA SCLFALLVGM VAGFFNGILV TWLRIPAIVA
TLGTLGLYRG LMLLLTGGKW IEGLPADLKS LSTPILFSIS PIGWLTMLLI LSMAWLLGNT
AFGRSFYATG DNLQGARQLG VRTDSIRIFA FSMNGVMAAL AGIVFASQIG FIPNQTGNGL
EMKAIAACVL GGISLLGGTG TIIGAILGAF LLTQIDSVLV LLRLPAWWND FIAGLVLLGV
LVFDGRLRCA VERNIRQQKY ARFTAQAIIS DKKPTVSDNN PAASNKKKAA L