ID   LSRD_KLEP7              Reviewed;         332 AA.
AC   A6TEB6;
DT   14-OCT-2008, integrated into UniProtKB/Swiss-Prot.
DT   21-AUG-2007, sequence version 1.
DT   25-MAY-2022, entry version 68.
DE   RecName: Full=Autoinducer 2 import system permease protein LsrD;
DE            Short=AI-2 import system permease protein LsrD;
GN   Name=lsrD; OrderedLocusNames=KPN78578_34760; ORFNames=KPN_03505;
OS   Klebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
OX   NCBI_TaxID=272620;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700721 / MGH 78578;
RG   The Klebsiella pneumonia Genome Sequencing Project;
RA   McClelland M., Sanderson E.K., Spieth J., Clifton W.S., Latreille P.,
RA   Sabo A., Pepin K., Bhonagiri V., Porwollik S., Ali J., Wilson R.K.;
RL   Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Part of the ABC transporter complex LsrABCD involved in
CC       autoinducer 2 (AI-2) import. Probably responsible for the translocation
CC       of the substrate across the membrane (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: The complex is composed of two ATP-binding proteins (LsrA),
CC       two transmembrane proteins (LsrC and LsrD) and a solute-binding protein
CC       (LsrB). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000250}; Multi-pass
CC       membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the binding-protein-dependent transport system
CC       permease family. AraH/RbsC subfamily. {ECO:0000305}.
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DR   EMBL; CP000647; ABR78900.1; -; Genomic_DNA.
DR   RefSeq; WP_015959042.1; NC_009648.1.
DR   AlphaFoldDB; A6TEB6; -.
DR   STRING; 272620.KPN_03505; -.
DR   EnsemblBacteria; ABR78900; ABR78900; KPN_03505.
DR   KEGG; kpn:KPN_03505; -.
DR   HOGENOM; CLU_028880_0_0_6; -.
DR   OMA; LSLHREW; -.
DR   Proteomes; UP000000265; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   InterPro; IPR001851; ABC_transp_permease.
DR   Pfam; PF02653; BPD_transp_2; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..332
FT                   /note="Autoinducer 2 import system permease protein LsrD"
FT                   /id="PRO_0000351369"
FT   TRANSMEM        5..25
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        43..63
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        83..103
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        116..136
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        160..180
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        210..230
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        259..279
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   332 AA;  34804 MW;  6997DE5618EC4D0D CRC64;
     MKLKLNWESA LLALLIAEIL LFGALNPRML DINMLLFSTS DFICIGIVAL PLTLVIISGG
     IDISLGSTIG LCAIALGVMT QAGWPLWLAV SLTLLLGLLC GLFNAALIHY TGINPLVITL
     GTLYLYGGGA LLLSGMAGAT GYEGIGGFPD SFTAFANLTL GGLPLPLVLF AIITFFFWLL
     AHRGRFGRHL FLLGQNPRAA RYAALSVNGI PYVLYGLVGV ASAVAALVMV SYFGSARSDL
     GRDLLMPALT AAVLGGANIY GGSGSILGTA LAALLVGYLQ QGLQMVGIPN QVSSALSGAL
     LVVVVMGRSL SLHREWVRAT WRRLFSHKTI GA