ID   LSRD_SALPA              Reviewed;         332 AA.
AC   Q5PJE5;
DT   14-OCT-2008, integrated into UniProtKB/Swiss-Prot.
DT   04-JAN-2005, sequence version 1.
DT   25-MAY-2022, entry version 70.
DE   RecName: Full=Autoinducer 2 import system permease protein LsrD;
DE            Short=AI-2 import system permease protein LsrD;
GN   Name=lsrD; OrderedLocusNames=SPA3919;
OS   Salmonella paratyphi A (strain ATCC 9150 / SARB42).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=295319;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 9150 / SARB42;
RX   PubMed=15531882; DOI=10.1038/ng1470;
RA   McClelland M., Sanderson K.E., Clifton S.W., Latreille P., Porwollik S.,
RA   Sabo A., Meyer R., Bieri T., Ozersky P., McLellan M., Harkins C.R.,
RA   Wang C., Nguyen C., Berghoff A., Elliott G., Kohlberg S., Strong C., Du F.,
RA   Carter J., Kremizki C., Layman D., Leonard S., Sun H., Fulton L., Nash W.,
RA   Miner T., Minx P., Delehaunty K., Fronick C., Magrini V., Nhan M.,
RA   Warren W., Florea L., Spieth J., Wilson R.K.;
RT   "Comparison of genome degradation in Paratyphi A and Typhi, human-
RT   restricted serovars of Salmonella enterica that cause typhoid.";
RL   Nat. Genet. 36:1268-1274(2004).
CC   -!- FUNCTION: Part of the ABC transporter complex LsrABCD involved in
CC       autoinducer 2 (AI-2) import. Probably responsible for the translocation
CC       of the substrate across the membrane (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: The complex is composed of two ATP-binding proteins (LsrA),
CC       two transmembrane proteins (LsrC and LsrD) and a solute-binding protein
CC       (LsrB). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000250}; Multi-pass
CC       membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the binding-protein-dependent transport system
CC       permease family. AraH/RbsC subfamily. {ECO:0000305}.
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DR   EMBL; CP000026; AAV79684.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q5PJE5; -.
DR   EnsemblBacteria; AAV79684; AAV79684; SPA3919.
DR   KEGG; spt:SPA3919; -.
DR   HOGENOM; CLU_028880_0_0_6; -.
DR   OMA; LSLHREW; -.
DR   Proteomes; UP000008185; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   InterPro; IPR001851; ABC_transp_permease.
DR   Pfam; PF02653; BPD_transp_2; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..332
FT                   /note="Autoinducer 2 import system permease protein LsrD"
FT                   /id="PRO_0000351374"
FT   TRANSMEM        7..27
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        45..65
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        70..90
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        91..111
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        118..138
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        162..182
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        216..236
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        240..260
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        261..281
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        288..308
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   332 AA;  35119 MW;  3C43342831C3758A CRC64;
     MNPWRRYSWE IALAALLIFE ILAFGVINPR LLDINVLLFS TSDFICIGIV ALPLTMVIVS
     GGMDISFGST IGLCAITLGV LFQLGMPLPL AIIITLLLGA ICGLINAGLI IYTGVNPLVI
     TLGTMYLFGG SALLLSGMAG ATGYEGIGGF PTAFTDFANI SFLGIPMPLI FFLVCCLFFW
     LLMHRTHMGR NVFLIGQSAR VAQYSAIPVN RTLYTVYAMT GCASAIAAVL LVSYFGSARS
     DLGASFLMPA ITAVVLGGAN IYGGSGSIMG SALAALLVGF LQQGLQMAGV PNQISSALSG
     ALLIVVVVGR SVSLHRHQIL EWYSRRRNAH QA