LST8_DROPS
ID LST8_DROPS Reviewed; 315 AA.
AC Q29HG9;
DT 08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT 04-APR-2006, sequence version 1.
DT 03-AUG-2022, entry version 83.
DE RecName: Full=Protein LST8 homolog;
GN ORFNames=GA15597;
OS Drosophila pseudoobscura pseudoobscura (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila; Sophophora.
OX NCBI_TaxID=46245;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MV2-25 / Tucson 14011-0121.94;
RX PubMed=15632085; DOI=10.1101/gr.3059305;
RA Richards S., Liu Y., Bettencourt B.R., Hradecky P., Letovsky S.,
RA Nielsen R., Thornton K., Hubisz M.J., Chen R., Meisel R.P., Couronne O.,
RA Hua S., Smith M.A., Zhang P., Liu J., Bussemaker H.J., van Batenburg M.F.,
RA Howells S.L., Scherer S.E., Sodergren E., Matthews B.B., Crosby M.A.,
RA Schroeder A.J., Ortiz-Barrientos D., Rives C.M., Metzker M.L., Muzny D.M.,
RA Scott G., Steffen D., Wheeler D.A., Worley K.C., Havlak P., Durbin K.J.,
RA Egan A., Gill R., Hume J., Morgan M.B., Miner G., Hamilton C., Huang Y.,
RA Waldron L., Verduzco D., Clerc-Blankenburg K.P., Dubchak I., Noor M.A.F.,
RA Anderson W., White K.P., Clark A.G., Schaeffer S.W., Gelbart W.M.,
RA Weinstock G.M., Gibbs R.A.;
RT "Comparative genome sequencing of Drosophila pseudoobscura: chromosomal,
RT gene, and cis-element evolution.";
RL Genome Res. 15:1-18(2005).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the WD repeat LST8 family. {ECO:0000305}.
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DR EMBL; CH379064; EAL31789.1; -; Genomic_DNA.
DR AlphaFoldDB; Q29HG9; -.
DR SMR; Q29HG9; -.
DR STRING; 7237.FBpp0287569; -.
DR eggNOG; KOG0315; Eukaryota.
DR HOGENOM; CLU_000288_57_5_1; -.
DR InParanoid; Q29HG9; -.
DR OMA; VQRNYKH; -.
DR PhylomeDB; Q29HG9; -.
DR Proteomes; UP000001819; Genome assembly.
DR GO; GO:0005737; C:cytoplasm; ISS:UniProtKB.
DR GO; GO:0031931; C:TORC1 complex; IEA:InterPro.
DR GO; GO:0031932; C:TORC2 complex; IEA:InterPro.
DR GO; GO:0031929; P:TOR signaling; IEA:InterPro.
DR Gene3D; 2.130.10.10; -; 1.
DR InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR InterPro; IPR037588; MLST8.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR001680; WD40_repeat.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR PANTHER; PTHR19842; PTHR19842; 1.
DR Pfam; PF00400; WD40; 5.
DR PRINTS; PR00320; GPROTEINBRPT.
DR SMART; SM00320; WD40; 6.
DR SUPFAM; SSF50978; SSF50978; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 2.
DR PROSITE; PS50082; WD_REPEATS_2; 4.
DR PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE 3: Inferred from homology;
KW Cytoplasm; Reference proteome; Repeat; WD repeat.
FT CHAIN 1..315
FT /note="Protein LST8 homolog"
FT /id="PRO_0000326506"
FT REPEAT 1..31
FT /note="WD 1"
FT REPEAT 33..71
FT /note="WD 2"
FT REPEAT 76..115
FT /note="WD 3"
FT REPEAT 119..158
FT /note="WD 4"
FT REPEAT 161..200
FT /note="WD 5"
FT REPEAT 211..250
FT /note="WD 6"
FT REPEAT 253..292
FT /note="WD 7"
FT REPEAT 295..315
FT /note="WD 8"
SQ SEQUENCE 315 AA; 35522 MW; 54FDA305906C3813 CRC64;
MGDQLILATG GYDHTIKVWQ AHTGNCIKTM RFVETSQVNA LDRTPDKTRL AACGYQCIRL
YDLESNCTAP VINFDGVQKN VTRLGFQEDG NWMFTAGEDH HVRIWDMISA PPHCSRVFDC
ESPVNAACLH PNQVEIGMGS QNGNVFLWDV KSEKHECIVP EVDASIQDVA ISPDGHYLAA
ANNKGNCYIW SLCSSPDQKM STMRPTKKIQ AHTRYILRCK FSPDSRLLLT TSGDGTACLW
KTSDFSKWRE LCIENYWVWD AAFSADSKWL FTASSDGVAR LWKLETKTPT REYTGHTKAI
TALSFKDEII RKVNH
