LSU2_ARATH
ID LSU2_ARATH Reviewed; 94 AA.
AC Q9FIR9;
DT 02-NOV-2016, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2001, sequence version 1.
DT 03-AUG-2022, entry version 110.
DE RecName: Full=Protein RESPONSE TO LOW SULFUR 2 {ECO:0000303|PubMed:25628631};
DE AltName: Full=Protein ENHANCED DE-ETIOLATION 6 {ECO:0000303|PubMed:22383539};
GN Name=LSU2 {ECO:0000303|PubMed:25628631};
GN Synonyms=END6 {ECO:0000303|PubMed:22383539};
GN OrderedLocusNames=At5g24660 {ECO:0000312|Araport:AT5G24660};
GN ORFNames=MXC17.2 {ECO:0000312|EMBL:BAB09648.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10048488; DOI=10.1093/dnares/5.6.379;
RA Asamizu E., Sato S., Kaneko T., Nakamura Y., Kotani H., Miyajima N.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. VIII. Sequence
RT features of the regions of 1,081,958 bp covered by seventeen physically
RT assigned P1 and TAC clones.";
RL DNA Res. 5:379-391(1998).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=11910074; DOI=10.1126/science.1071006;
RA Seki M., Narusaka M., Kamiya A., Ishida J., Satou M., Sakurai T.,
RA Nakajima M., Enju A., Akiyama K., Oono Y., Muramatsu M., Hayashizaki Y.,
RA Kawai J., Carninci P., Itoh M., Ishii Y., Arakawa T., Shibata K.,
RA Shinagawa A., Shinozaki K.;
RT "Functional annotation of a full-length Arabidopsis cDNA collection.";
RL Science 296:141-145(2002).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [6]
RP INDUCTION BY SULFUR DEFICIENCY.
RX PubMed=15842617; DOI=10.1111/j.1365-313x.2005.02363.x;
RA Maruyama-Nakashita A., Nakamura Y., Watanabe-Takahashi A., Inoue E.,
RA Yamaya T., Takahashi H.;
RT "Identification of a novel cis-acting element conferring sulfur deficiency
RT response in Arabidopsis roots.";
RL Plant J. 42:305-314(2005).
RN [7]
RP FUNCTION, AND DISRUPTION PHENOTYPE.
RC STRAIN=cv. Columbia;
RX PubMed=21798943; DOI=10.1126/science.1203659;
RG European Union Effectoromics Consortium;
RA Mukhtar M.S., Carvunis A.-R., Dreze M., Epple P., Steinbrenner J.,
RA Moore J., Tasan M., Galli M., Hao T., Nishimura M.T., Pevzner S.J.,
RA Donovan S.E., Ghamsari L., Santhanam B., Romero V., Poulin M.M.,
RA Gebreab F., Gutierrez B.J., Tam S., Monachello D., Boxem M., Harbort C.J.,
RA McDonald N., Gai L., Chen H., He Y., Vandenhaute J., Roth F.P., Hill D.E.,
RA Ecker J.R., Vidal M., Beynon J., Braun P., Dangl J.L.;
RT "Independently evolved virulence effectors converge onto hubs in a plant
RT immune system network.";
RL Science 333:596-601(2011).
RN [8]
RP INDUCTION BY LIGHT AND PLASTID SIGNALING.
RX PubMed=22383539; DOI=10.1104/pp.112.193599;
RA Ruckle M.E., Burgoon L.D., Lawrence L.A., Sinkler C.A., Larkin R.M.;
RT "Plastids are major regulators of light signaling in Arabidopsis.";
RL Plant Physiol. 159:366-390(2012).
RN [9]
RP FUNCTION, AND DISRUPTION PHENOTYPE.
RX PubMed=23517122; DOI=10.1111/ppl.12013;
RA Luhua S., Hegie A., Suzuki N., Shulaev E., Luo X., Cenariu D., Ma V.,
RA Kao S., Lim J., Gunay M.B., Oosumi T., Lee S.C., Harper J., Cushman J.,
RA Gollery M., Girke T., Bailey-Serres J., Stevenson R.A., Zhu J.-K.,
RA Mittler R.;
RT "Linking genes of unknown function with abiotic stress responses by high-
RT throughput phenotype screening.";
RL Physiol. Plantarum 148:322-333(2013).
RN [10]
RP INDUCTION BY STRESSFUL ENVIRONMENTAL CONDITIONS, REVIEW, GENE FAMILY, AND
RP NOMENCLATURE.
RX PubMed=25628631; DOI=10.3389/fpls.2014.00774;
RA Sirko A., Wawrzynska A., Rodriguez M.C., Sektas P.;
RT "The family of LSU-like proteins.";
RL Front. Plant Sci. 5:774-774(2014).
CC -!- FUNCTION: May be involved in defense responses monitoring
CC (PubMed:21798943). Probably implicated into osmotic stress signaling
CC (PubMed:23517122). {ECO:0000269|PubMed:21798943,
CC ECO:0000269|PubMed:23517122}.
CC -!- INTERACTION:
CC Q9FIR9; Q94ID6: ERF12; NbExp=4; IntAct=EBI-4424076, EBI-4446727;
CC Q9FIR9; Q9FYK5: ESR2; NbExp=3; IntAct=EBI-4424076, EBI-1536925;
CC Q9FIR9; Q8GXL7: GATA24; NbExp=3; IntAct=EBI-4424076, EBI-4426127;
CC Q9FIR9; Q8RXD6: HUB1; NbExp=3; IntAct=EBI-4424076, EBI-2012188;
CC Q9FIR9; Q5ICL9: NPR4; NbExp=3; IntAct=EBI-4424076, EBI-1392093;
CC Q9FIR9; Q84MB2: TIFY8; NbExp=3; IntAct=EBI-4424076, EBI-4426557;
CC Q9FIR9; Q5CCK4: VAL2; NbExp=3; IntAct=EBI-4424076, EBI-15193683;
CC -!- INDUCTION: By stressful environmental conditions such as salt stress,
CC AgNO(3), and sulfur deficiency (PubMed:15842617, PubMed:25628631).
CC Induced during oxidative stress (PubMed:25628631). Accumulates at the
CC beginning of an extended night, which may indicate that it is induced
CC by carbon starvation and in response to sugar (PubMed:25628631).
CC Induced by a combination of light and plastid signaling
CC (PubMed:22383539). {ECO:0000269|PubMed:15842617,
CC ECO:0000269|PubMed:22383539, ECO:0000303|PubMed:25628631}.
CC -!- DISRUPTION PHENOTYPE: Enhanced tolerance to osmotic stress
CC (PubMed:23517122). Increased susceptibility to pathogens such as
CC P.syringae and H.arabidopsidis (PubMed:21798943).
CC {ECO:0000269|PubMed:21798943, ECO:0000269|PubMed:23517122}.
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DR EMBL; AB016881; BAB09648.1; -; Genomic_DNA.
DR EMBL; CP002688; AED93346.1; -; Genomic_DNA.
DR EMBL; AK118602; BAC43201.1; -; mRNA.
DR EMBL; BT004681; AAO42927.1; -; mRNA.
DR EMBL; AY086698; AAM63752.1; -; mRNA.
DR RefSeq; NP_197854.1; NM_122375.3.
DR AlphaFoldDB; Q9FIR9; -.
DR SMR; Q9FIR9; -.
DR IntAct; Q9FIR9; 44.
DR STRING; 3702.AT5G24660.1; -.
DR PaxDb; Q9FIR9; -.
DR PRIDE; Q9FIR9; -.
DR EnsemblPlants; AT5G24660.1; AT5G24660.1; AT5G24660.
DR GeneID; 832538; -.
DR Gramene; AT5G24660.1; AT5G24660.1; AT5G24660.
DR KEGG; ath:AT5G24660; -.
DR Araport; AT5G24660; -.
DR TAIR; locus:2176811; AT5G24660.
DR eggNOG; ENOG502SZ0Q; Eukaryota.
DR HOGENOM; CLU_152833_0_0_1; -.
DR InParanoid; Q9FIR9; -.
DR OMA; RIIFLMN; -.
DR OrthoDB; 1598998at2759; -.
DR PhylomeDB; Q9FIR9; -.
DR PRO; PR:Q9FIR9; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q9FIR9; baseline and differential.
DR GO; GO:0098869; P:cellular oxidant detoxification; IEA:InterPro.
DR GO; GO:0010438; P:cellular response to sulfur starvation; IEP:UniProtKB.
DR GO; GO:0009658; P:chloroplast organization; IMP:TAIR.
DR GO; GO:0042742; P:defense response to bacterium; IMP:UniProtKB.
DR GO; GO:0002229; P:defense response to oomycetes; IMP:UniProtKB.
DR GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IMP:TAIR.
DR GO; GO:0031347; P:regulation of defense response; IMP:TAIR.
DR GO; GO:0047484; P:regulation of response to osmotic stress; IMP:UniProtKB.
DR GO; GO:0009651; P:response to salt stress; IEP:UniProtKB.
DR InterPro; IPR039282; LSU.
DR PANTHER; PTHR34283; PTHR34283; 1.
PE 1: Evidence at protein level;
KW Coiled coil; Plant defense; Reference proteome.
FT CHAIN 1..94
FT /note="Protein RESPONSE TO LOW SULFUR 2"
FT /id="PRO_0000437693"
FT DOMAIN 14..61
FT /note="Death"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00064"
FT COILED 15..63
FT /evidence="ECO:0000255"
SQ SEQUENCE 94 AA; 10679 MW; D8869AEDAA0378D5 CRC64;
MGKGGNYVTV AASEVDELRR KNGEMEKAVE EMKKEMLQLW RRTQVAEEAE ERLCSQLAEL
EAESLDQARD YHSRIIFLMN ELSRLSSDSA SASP
