LTG21_ARATH
ID LTG21_ARATH Reviewed; 205 AA.
AC Q1G2Y5; A0MFR9; Q9LR49;
DT 02-DEC-2020, integrated into UniProtKB/Swiss-Prot.
DT 27-JUN-2006, sequence version 1.
DT 03-AUG-2022, entry version 117.
DE RecName: Full=Non-specific lipid transfer protein GPI-anchored 21 {ECO:0000303|PubMed:23893219};
DE Short=AtLTPG-21 {ECO:0000303|PubMed:23893219};
DE Short=Protein LTP-GPI-ANCHORED 21 {ECO:0000303|PubMed:23893219};
DE Flags: Precursor;
GN Name=LTPG21 {ECO:0000303|PubMed:23893219};
GN OrderedLocusNames=At1g05450 {ECO:0000312|Araport:AT1G05450};
GN ORFNames=T25N20.10 {ECO:0000312|EMBL:AAF79724.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=17147637; DOI=10.1111/j.1467-7652.2006.00183.x;
RA Underwood B.A., Vanderhaeghen R., Whitford R., Town C.D., Hilson P.;
RT "Simultaneous high-throughput recombinational cloning of open reading
RT frames in closed and open configurations.";
RL Plant Biotechnol. J. 4:317-324(2006).
RN [4]
RP GENE FAMILY, AND NOMENCLATURE.
RC STRAIN=cv. Columbia;
RX PubMed=23893219; DOI=10.1007/s11103-013-0113-5;
RA Edstam M.M., Blomqvist K., Ekloef A., Wennergren U., Edqvist J.;
RT "Coexpression patterns indicate that GPI-anchored non-specific lipid
RT transfer proteins are involved in accumulation of cuticular wax, suberin
RT and sporopollenin.";
RL Plant Mol. Biol. 83:625-649(2013).
CC -!- FUNCTION: Probable lipid transfer protein.
CC {ECO:0000250|UniProtKB:Q9C7F7}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255}; Lipid-anchor, GPI-
CC anchor {ECO:0000255}.
CC -!- SIMILARITY: Belongs to the plant LTP family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAF79724.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=ABK28778.1; Type=Erroneous termination; Note=Extended C-terminus.; Evidence={ECO:0000305};
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DR EMBL; AC005106; AAF79724.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002684; AEE27841.1; -; Genomic_DNA.
DR EMBL; DQ492243; ABF59172.1; -; mRNA.
DR EMBL; DQ653396; ABK28778.1; ALT_SEQ; mRNA.
DR RefSeq; NP_973763.1; NM_202034.3.
DR AlphaFoldDB; Q1G2Y5; -.
DR STRING; 3702.AT1G05450.2; -.
DR PaxDb; Q1G2Y5; -.
DR PRIDE; Q1G2Y5; -.
DR ProteomicsDB; 185439; -.
DR EnsemblPlants; AT1G05450.2; AT1G05450.2; AT1G05450.
DR GeneID; 837046; -.
DR Gramene; AT1G05450.2; AT1G05450.2; AT1G05450.
DR KEGG; ath:AT1G05450; -.
DR Araport; AT1G05450; -.
DR TAIR; locus:2201046; AT1G05450.
DR eggNOG; ENOG502RZXE; Eukaryota.
DR HOGENOM; CLU_085549_3_0_1; -.
DR InParanoid; Q1G2Y5; -.
DR OMA; MDPDGMP; -.
DR OrthoDB; 1573578at2759; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q1G2Y5; baseline and differential.
DR GO; GO:0031225; C:anchored component of membrane; TAS:TAIR.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR Gene3D; 1.10.110.10; -; 1.
DR InterPro; IPR036312; Bifun_inhib/LTP/seed_sf.
DR InterPro; IPR016140; Bifunc_inhib/LTP/seed_store.
DR InterPro; IPR043325; LTSS.
DR PANTHER; PTHR33044; PTHR33044; 1.
DR Pfam; PF14368; LTP_2; 1.
DR SMART; SM00499; AAI; 1.
DR SUPFAM; SSF47699; SSF47699; 1.
PE 2: Evidence at transcript level;
KW Cell membrane; Disulfide bond; Glycoprotein; GPI-anchor; Lipoprotein;
KW Membrane; Reference proteome; Signal.
FT SIGNAL 1..27
FT /evidence="ECO:0000255"
FT CHAIN 28..179
FT /note="Non-specific lipid transfer protein GPI-anchored 21"
FT /id="PRO_5014308292"
FT PROPEP 180..205
FT /note="Removed in mature form"
FT /evidence="ECO:0000255"
FT /id="PRO_0000451652"
FT REGION 116..182
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 125..162
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT LIPID 179
FT /note="GPI-anchor amidated serine"
FT /evidence="ECO:0000255"
FT CARBOHYD 89
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT DISULFID 33..75
FT /evidence="ECO:0000250|UniProtKB:A0A0B4JDK1"
FT DISULFID 44..59
FT /evidence="ECO:0000250|UniProtKB:A0A0B4JDK1"
FT DISULFID 60..100
FT /evidence="ECO:0000250|UniProtKB:A0A0B4JDK1"
FT DISULFID 73..109
FT /evidence="ECO:0000250|UniProtKB:A0A0B4JDK1"
SQ SEQUENCE 205 AA; 20621 MW; CD049B3FE271B27F CRC64;
MNSNSFLISA ALIFSLLSSN SPTSILAQIN TPCSPSMLSS VTGCTSFLTG GGSFPTSDCC
GALKSLTGTG MDCLCLIVTA GVPISIPINR TLAISLPRAC GIPGVPVQCK ASAAPLPTPG
PASFGPTTSP TDSQTSDPEG SASFRPPTSP TTSQTPNDKD LSGSGNGGDP MGFAPPPPSS
SPSSSHSLKL SYLLFAFAFT IIKFI
