ID   LTRA_KLEPN              Reviewed;         309 AA.
AC   P52689;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1996, sequence version 1.
DT   25-MAY-2022, entry version 86.
DE   RecName: Full=Probable HTH-type transcriptional regulator LtrA;
GN   Name=ltrA;
OS   Klebsiella pneumoniae.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
OX   NCBI_TaxID=573;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 13882 / NBRC 13541 / NCTC 8172;
RX   PubMed=8748036; DOI=10.1111/j.1365-2958.1995.mmi_18030533.x;
RA   Bott M., Meyer M., Dimroth P.;
RT   "Regulation of anaerobic citrate metabolism in Klebsiella pneumoniae.";
RL   Mol. Microbiol. 18:533-546(1995).
CC   -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC       {ECO:0000305}.
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DR   EMBL; U31464; AAC44735.1; -; Genomic_DNA.
DR   PIR; S70535; S70535.
DR   RefSeq; WP_004178570.1; NZ_WYAM01000022.1.
DR   AlphaFoldDB; P52689; -.
DR   SMR; P52689; -.
DR   PRIDE; P52689; -.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR005119; LysR_subst-bd.
DR   InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF00126; HTH_1; 1.
DR   Pfam; PF03466; LysR_substrate; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   PROSITE; PS50931; HTH_LYSR; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Transcription; Transcription regulation.
FT   CHAIN           1..309
FT                   /note="Probable HTH-type transcriptional regulator LtrA"
FT                   /id="PRO_0000105666"
FT   DOMAIN          1..61
FT                   /note="HTH lysR-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00253"
FT   DNA_BIND        21..40
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00253"
SQ   SEQUENCE   309 AA;  34357 MW;  5C54D416605C734A CRC64;
     MNLNLLPDLA LFVQIVDQGS FSAVARQNGI TPSAVSRSVS RLEREMGCKL LQRTTRKLRL
     SDAGETIYQH AQQMLEAARQ AMDSAGSRQT VAQGKLTLSV PKAVGRFVIH PLMMAFFHRY
     PQVDVCLRLE DRPLDFIDDG IDLALRITDT PSPGLHGKPL MPIRHVICAT EAYLQQHGTP
     YTPQDLRAHS CISLGETPAD ARWKFRREGK TETVQTYGRY AANHTAVRLD AVRQHLGIGS
     LPLFTAREAL ANGDIVQVLP EWEFISSYSG DLWLLWAGDK HMPARMRAMI DYLSETVPAL
     NAGSTEPAK