ID   LTX2A_NEOIV             Reviewed;          24 AA.
AC   P0DSJ3;
DT   08-MAY-2019, integrated into UniProtKB/Swiss-Prot.
DT   08-MAY-2019, sequence version 1.
DT   25-MAY-2022, entry version 7.
DE   RecName: Full=U1-poneritoxin-Ni2a {ECO:0000303|PubMed:26805882};
DE            Short=U1-PONTX-Ni2a {ECO:0000303|PubMed:26805882};
DE   AltName: Full=Poneratoxin {ECO:0000305};
DE   AltName: Full=Ponericin Pi III1 {ECO:0000303|PubMed:25448389};
OS   Neoponera inversa (Ant) (Ponera inversa).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC   Formicidae; Ponerinae; Ponerini; Neoponera.
OX   NCBI_TaxID=264722;
RN   [1]
RP   REVIEW, AND PROTEIN SEQUENCE.
RX   PubMed=25448389; DOI=10.1016/j.toxicon.2014.10.021;
RA   Aili S.R., Touchard A., Escoubas P., Padula M.P., Orivel J., Dejean A.,
RA   Nicholson G.M.;
RT   "Diversity of peptide toxins from stinging ant venoms.";
RL   Toxicon 92:166-178(2014).
RN   [2]
RP   REVIEW, AND NOMENCLATURE.
RX   PubMed=26805882; DOI=10.3390/toxins8010030;
RA   Touchard A., Aili S.R., Fox E.G., Escoubas P., Orivel J., Nicholson G.M.,
RA   Dejean A.;
RT   "The biochemical toxin arsenal from ant venoms.";
RL   Toxins 8:1-28(2016).
CC   -!- FUNCTION: Has a broad spectrum of activity against both Gram-positive
CC       and Gram-negative bacteria. Is inactive against yeast, erythrocytes,
CC       and insects. {ECO:0000250|UniProtKB:P82422}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305|PubMed:25448389}.
CC   -!- TISSUE SPECIFICITY: Expressed by the venom gland.
CC       {ECO:0000305|PubMed:25448389}.
CC   -!- SIMILARITY: Belongs to the ponericin-L family. {ECO:0000305}.
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DR   AlphaFoldDB; P0DSJ3; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
DR   GO; GO:0045087; P:innate immune response; IEA:InterPro.
DR   InterPro; IPR012528; Antimicrobial_9.
DR   Pfam; PF08104; Antimicrobial_9; 1.
PE   1: Evidence at protein level;
KW   Antibiotic; Antimicrobial; Direct protein sequencing; Secreted.
FT   PEPTIDE         1..24
FT                   /note="U1-poneritoxin-Ni2a"
FT                   /id="PRO_0000447063"
SQ   SEQUENCE   24 AA;  2605 MW;  37956187B1515E8F CRC64;
     LLKELWKKIK GAGKAVLGKI KGLL