LUCB_OPLGR
ID LUCB_OPLGR Reviewed; 359 AA.
AC Q9GV46;
DT 05-SEP-2012, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2001, sequence version 1.
DT 25-MAY-2022, entry version 50.
DE RecName: Full=Oplophorus-luciferin 2-monooxygenase non-catalytic subunit;
DE Flags: Precursor;
OS Oplophorus gracilirostris (Luminous shrimp).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Crustacea; Multicrustacea;
OC Malacostraca; Eumalacostraca; Eucarida; Decapoda; Pleocyemata; Caridea;
OC Oplophoroidea; Oplophoridae; Oplophorus.
OX NCBI_TaxID=727944;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], PARTIAL PROTEIN SEQUENCE, FUNCTION, AND
RP SUBUNIT.
RX PubMed=10984608; DOI=10.1016/s0014-5793(00)01963-3;
RA Inouye S., Watanabe K., Nakamura H., Shimomura O.;
RT "Secretional luciferase of the luminous shrimp Oplophorus gracilirostris:
RT cDNA cloning of a novel imidazopyrazinone luciferase(1).";
RL FEBS Lett. 481:19-25(2000).
CC -!- FUNCTION: Non-catalytic subunit of oplophorus-luciferin 2-
CC monooxygenase. May stabilize the active conformation of the catalytic
CC subunit. {ECO:0000269|PubMed:10984608}.
CC -!- SUBUNIT: Heterotetramer of a catalytic 19 kDa and a non-catalytic 35
CC kDa subunit. {ECO:0000269|PubMed:10984608}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC -!- MISCELLANEOUS: The shrimp has luminous glands at the base of its
CC antennae and legs, and ejects a cloud of brightly luminescent secretion
CC from the base of its antennae upon stimulation.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AB030245; BAB13775.1; -; mRNA.
DR AlphaFoldDB; Q9GV46; -.
DR SMR; Q9GV46; -.
DR KEGG; ag:BAB13775; -.
DR BRENDA; 1.13.12.13; 4421.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR Gene3D; 3.80.10.10; -; 2.
DR InterPro; IPR032675; LRR_dom_sf.
PE 1: Evidence at protein level;
KW Direct protein sequencing; Leucine-rich repeat; Repeat; Secreted; Signal.
FT SIGNAL 1..39
FT /evidence="ECO:0000305"
FT CHAIN 40..359
FT /note="Oplophorus-luciferin 2-monooxygenase non-catalytic
FT subunit"
FT /id="PRO_0000418819"
FT REPEAT 135..158
FT /note="LRR 1"
FT REPEAT 160..180
FT /note="LRR 2"
FT REPEAT 181..203
FT /note="LRR 3"
FT REPEAT 228..251
FT /note="LRR 4"
FT REPEAT 255..278
FT /note="LRR 5"
FT REPEAT 280..300
FT /note="LRR 6"
FT REPEAT 302..325
FT /note="LRR 7"
FT REPEAT 331..356
FT /note="LRR 8"
SQ SEQUENCE 359 AA; 39152 MW; 5D82E3E12DEF9F4D CRC64;
MAVNFKFSLL TITIVVNILV YCNASAIKFD VDLEKVPSNA VACPAAEDIA PCTCKVGEGD
VMDMDCSKVT SDAELASIFS KTFPSNTFRE LFIEFNREIT TLTADSLGAA TFTKIAITSC
TQLKTIEENA FMASAATLEK LVLLKNDLSS FPFEEMSQYT KLNWLELSVN SITGWPALSS
DTLANLILFR NPIGNIPVDA FQTLPNIEQF NCFDCSITEV EAGTFTRSPK LQKLVLGYNG
LTSLPVGAIK LHGHGPTTSN LGITNNQIIS FPEGAVEGIQ GILGIDFNRV TSLSEEVWRP
ILENLFQFSL LNNPLACVCD VMWLIDSPEL LAKIKGNPRC AGGKRLKNLD PAVFHAMCQ