ID   LUKL1_STAA3             Reviewed;         338 AA.
AC   Q2FFA3;
DT   21-AUG-2007, integrated into UniProtKB/Swiss-Prot.
DT   21-MAR-2006, sequence version 1.
DT   03-AUG-2022, entry version 79.
DE   RecName: Full=Uncharacterized leukocidin-like protein 1;
DE   Flags: Precursor;
GN   OrderedLocusNames=SAUSA300_1974;
OS   Staphylococcus aureus (strain USA300).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=367830;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=USA300;
RX   PubMed=16517273; DOI=10.1016/s0140-6736(06)68231-7;
RA   Diep B.A., Gill S.R., Chang R.F., Phan T.H., Chen J.H., Davidson M.G.,
RA   Lin F., Lin J., Carleton H.A., Mongodin E.F., Sensabaugh G.F.,
RA   Perdreau-Remington F.;
RT   "Complete genome sequence of USA300, an epidemic clone of community-
RT   acquired meticillin-resistant Staphylococcus aureus.";
RL   Lancet 367:731-739(2006).
CC   -!- SIMILARITY: Belongs to the aerolysin family. {ECO:0000305}.
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DR   EMBL; CP000255; ABD21470.1; -; Genomic_DNA.
DR   RefSeq; WP_000595324.1; NZ_CP027476.1.
DR   AlphaFoldDB; Q2FFA3; -.
DR   SMR; Q2FFA3; -.
DR   PRIDE; Q2FFA3; -.
DR   ABCD; Q2FFA3; 1 sequenced antibody.
DR   EnsemblBacteria; ABD21470; ABD21470; SAUSA300_1974.
DR   KEGG; saa:SAUSA300_1974; -.
DR   HOGENOM; CLU_055394_0_1_9; -.
DR   OMA; EPNGYWN; -.
DR   Proteomes; UP000001939; Chromosome.
DR   GO; GO:0005576; C:extracellular region; IEA:InterPro.
DR   GO; GO:0051715; P:cytolysis in another organism; IEA:InterPro.
DR   InterPro; IPR003963; Bi-component_toxin_staph.
DR   InterPro; IPR016183; Leukocidin/Hemolysin_toxin.
DR   InterPro; IPR036435; Leukocidin/porin_MspA_sf.
DR   Pfam; PF07968; Leukocidin; 1.
DR   PRINTS; PR01468; BICOMPNTOXIN.
DR   SUPFAM; SSF56959; SSF56959; 1.
DR   TIGRFAMs; TIGR01002; hlyII; 1.
PE   3: Inferred from homology;
KW   Signal.
FT   SIGNAL          1..29
FT                   /evidence="ECO:0000255"
FT   CHAIN           30..338
FT                   /note="Uncharacterized leukocidin-like protein 1"
FT                   /id="PRO_0000298638"
SQ   SEQUENCE   338 AA;  38686 MW;  47B194756D50C33E CRC64;
     MIKQLCKNIT ICTLALSTTF TVLPATSFAK INSEIKQVSE KNLDGDTKMY TRTATTSDSQ
     KNITQSLQFN FLTEPNYDKE TVFIKAKGTI GSGLRILDPN GYWNSTLRWP GSYSVSIQNV
     DDNNNTNVTD FAPKNQDESR EVKYTYGYKT GGDFSINRGG LTGNITKESN YSETISYQQP
     SYRTLLDQST SHKGVGWKVE AHLINNMGHD HTRQLTNDSD NRTKSEIFSL TRNGNLWAKD
     NFTPKDKMPV TVSEGFNPEF LAVMSHDKKD KGKSQFVVHY KRSMDEFKID WNRHGFWGYW
     SGENHVDKKE EKLSALYEVD WKTHNVKFVK VLNDNEKK