ID   LUKL1_STAAM             Reviewed;         338 AA.
AC   Q99SN8;
DT   21-AUG-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2001, sequence version 1.
DT   03-AUG-2022, entry version 99.
DE   RecName: Full=Uncharacterized leukocidin-like protein 1;
DE   Flags: Precursor;
GN   OrderedLocusNames=SAV2004;
OS   Staphylococcus aureus (strain Mu50 / ATCC 700699).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=158878;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Mu50 / ATCC 700699;
RX   PubMed=11418146; DOI=10.1016/s0140-6736(00)04403-2;
RA   Kuroda M., Ohta T., Uchiyama I., Baba T., Yuzawa H., Kobayashi I., Cui L.,
RA   Oguchi A., Aoki K., Nagai Y., Lian J.-Q., Ito T., Kanamori M.,
RA   Matsumaru H., Maruyama A., Murakami H., Hosoyama A., Mizutani-Ui Y.,
RA   Takahashi N.K., Sawano T., Inoue R., Kaito C., Sekimizu K., Hirakawa H.,
RA   Kuhara S., Goto S., Yabuzaki J., Kanehisa M., Yamashita A., Oshima K.,
RA   Furuya K., Yoshino C., Shiba T., Hattori M., Ogasawara N., Hayashi H.,
RA   Hiramatsu K.;
RT   "Whole genome sequencing of meticillin-resistant Staphylococcus aureus.";
RL   Lancet 357:1225-1240(2001).
CC   -!- SIMILARITY: Belongs to the aerolysin family. {ECO:0000305}.
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DR   EMBL; BA000017; BAB58166.1; -; Genomic_DNA.
DR   RefSeq; WP_000595392.1; NC_002758.2.
DR   AlphaFoldDB; Q99SN8; -.
DR   SMR; Q99SN8; -.
DR   PaxDb; Q99SN8; -.
DR   EnsemblBacteria; BAB58166; BAB58166; SAV2004.
DR   KEGG; sav:SAV2004; -.
DR   HOGENOM; CLU_055394_0_1_9; -.
DR   OMA; EPNGYWN; -.
DR   PhylomeDB; Q99SN8; -.
DR   BioCyc; SAUR158878:SAV_RS10955-MON; -.
DR   Proteomes; UP000002481; Chromosome.
DR   GO; GO:0005576; C:extracellular region; IEA:InterPro.
DR   GO; GO:0051715; P:cytolysis in another organism; IEA:InterPro.
DR   InterPro; IPR003963; Bi-component_toxin_staph.
DR   InterPro; IPR016183; Leukocidin/Hemolysin_toxin.
DR   InterPro; IPR036435; Leukocidin/porin_MspA_sf.
DR   Pfam; PF07968; Leukocidin; 1.
DR   PRINTS; PR01468; BICOMPNTOXIN.
DR   SUPFAM; SSF56959; SSF56959; 1.
DR   TIGRFAMs; TIGR01002; hlyII; 1.
PE   3: Inferred from homology;
KW   Signal.
FT   SIGNAL          1..29
FT                   /evidence="ECO:0000255"
FT   CHAIN           30..338
FT                   /note="Uncharacterized leukocidin-like protein 1"
FT                   /id="PRO_0000298634"
SQ   SEQUENCE   338 AA;  38662 MW;  B4B4F335B4B8D8B1 CRC64;
     MIKQLYKNIT ICSLAISTAL TVFPATSYAK INSEIKAVSE KNLDGDTKMY TRTATTSDSQ
     KNITQSLQFN FLTEPNYDKE TVFIKAKGTI GSGLRILDPN GYWNSTLRWP GSYSVSIQNV
     DDNNNTNVTD FAPKNQDESR EVKYTYGYKT GGDFSINRGG LTGNITKESN YSETISYQQP
     SYRTLLDQST SHKGVGWKVE AHLINNMGHD HTRQLTNDSD NRTKSEIFSL TRNGNLWAKD
     NFTPKDKMPV TVSEGFNPEF LAVMSHDKKD KGKSQFVVHY KRSMDEFKID WNRHGFWGYW
     SGENHVDKKE EKLSALYEVD WKTHDVKFVK VLNDNEKK