ID   LUKL1_STAAN             Reviewed;         338 AA.
AC   Q7A4L0;
DT   21-AUG-2007, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 89.
DE   RecName: Full=Uncharacterized leukocidin-like protein 1;
DE   Flags: Precursor;
GN   OrderedLocusNames=SA1812;
OS   Staphylococcus aureus (strain N315).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=158879;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=N315;
RX   PubMed=11418146; DOI=10.1016/s0140-6736(00)04403-2;
RA   Kuroda M., Ohta T., Uchiyama I., Baba T., Yuzawa H., Kobayashi I., Cui L.,
RA   Oguchi A., Aoki K., Nagai Y., Lian J.-Q., Ito T., Kanamori M.,
RA   Matsumaru H., Maruyama A., Murakami H., Hosoyama A., Mizutani-Ui Y.,
RA   Takahashi N.K., Sawano T., Inoue R., Kaito C., Sekimizu K., Hirakawa H.,
RA   Kuhara S., Goto S., Yabuzaki J., Kanehisa M., Yamashita A., Oshima K.,
RA   Furuya K., Yoshino C., Shiba T., Hattori M., Ogasawara N., Hayashi H.,
RA   Hiramatsu K.;
RT   "Whole genome sequencing of meticillin-resistant Staphylococcus aureus.";
RL   Lancet 357:1225-1240(2001).
RN   [2]
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC   STRAIN=N315;
RA   Vaezzadeh A.R., Deshusses J., Lescuyer P., Hochstrasser D.F.;
RT   "Shotgun proteomic analysis of total and membrane protein extracts of S.
RT   aureus strain N315.";
RL   Submitted (OCT-2007) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the aerolysin family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; BA000018; BAB43092.1; -; Genomic_DNA.
DR   PIR; C89991; C89991.
DR   RefSeq; WP_000595392.1; NC_002745.2.
DR   AlphaFoldDB; Q7A4L0; -.
DR   SMR; Q7A4L0; -.
DR   EnsemblBacteria; BAB43092; BAB43092; BAB43092.
DR   KEGG; sau:SA1812; -.
DR   HOGENOM; CLU_055394_0_1_9; -.
DR   OMA; EPNGYWN; -.
DR   Proteomes; UP000000751; Chromosome.
DR   GO; GO:0005576; C:extracellular region; IEA:InterPro.
DR   GO; GO:0051715; P:cytolysis in another organism; IEA:InterPro.
DR   InterPro; IPR003963; Bi-component_toxin_staph.
DR   InterPro; IPR016183; Leukocidin/Hemolysin_toxin.
DR   InterPro; IPR036435; Leukocidin/porin_MspA_sf.
DR   Pfam; PF07968; Leukocidin; 1.
DR   PRINTS; PR01468; BICOMPNTOXIN.
DR   SUPFAM; SSF56959; SSF56959; 1.
DR   TIGRFAMs; TIGR01002; hlyII; 1.
PE   1: Evidence at protein level;
KW   Signal.
FT   SIGNAL          1..29
FT                   /evidence="ECO:0000255"
FT   CHAIN           30..338
FT                   /note="Uncharacterized leukocidin-like protein 1"
FT                   /id="PRO_0000298636"
SQ   SEQUENCE   338 AA;  38662 MW;  B4B4F335B4B8D8B1 CRC64;
     MIKQLYKNIT ICSLAISTAL TVFPATSYAK INSEIKAVSE KNLDGDTKMY TRTATTSDSQ
     KNITQSLQFN FLTEPNYDKE TVFIKAKGTI GSGLRILDPN GYWNSTLRWP GSYSVSIQNV
     DDNNNTNVTD FAPKNQDESR EVKYTYGYKT GGDFSINRGG LTGNITKESN YSETISYQQP
     SYRTLLDQST SHKGVGWKVE AHLINNMGHD HTRQLTNDSD NRTKSEIFSL TRNGNLWAKD
     NFTPKDKMPV TVSEGFNPEF LAVMSHDKKD KGKSQFVVHY KRSMDEFKID WNRHGFWGYW
     SGENHVDKKE EKLSALYEVD WKTHDVKFVK VLNDNEKK