LUKL2_STAA3
ID LUKL2_STAA3 Reviewed; 351 AA.
AC Q2FFA2;
DT 21-AUG-2007, integrated into UniProtKB/Swiss-Prot.
DT 21-MAR-2006, sequence version 1.
DT 25-MAY-2022, entry version 79.
DE RecName: Full=Uncharacterized leukocidin-like protein 2;
DE Flags: Precursor;
GN OrderedLocusNames=SAUSA300_1975;
OS Staphylococcus aureus (strain USA300).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC Staphylococcus.
OX NCBI_TaxID=367830;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=USA300;
RX PubMed=16517273; DOI=10.1016/s0140-6736(06)68231-7;
RA Diep B.A., Gill S.R., Chang R.F., Phan T.H., Chen J.H., Davidson M.G.,
RA Lin F., Lin J., Carleton H.A., Mongodin E.F., Sensabaugh G.F.,
RA Perdreau-Remington F.;
RT "Complete genome sequence of USA300, an epidemic clone of community-
RT acquired meticillin-resistant Staphylococcus aureus.";
RL Lancet 367:731-739(2006).
CC -!- SIMILARITY: Belongs to the aerolysin family. {ECO:0000305}.
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DR EMBL; CP000255; ABD22526.1; -; Genomic_DNA.
DR RefSeq; WP_000791407.1; NZ_CP027476.1.
DR AlphaFoldDB; Q2FFA2; -.
DR SMR; Q2FFA2; -.
DR EnsemblBacteria; ABD22526; ABD22526; SAUSA300_1975.
DR KEGG; saa:SAUSA300_1975; -.
DR HOGENOM; CLU_865755_0_0_9; -.
DR OMA; HWSVVAN; -.
DR Proteomes; UP000001939; Chromosome.
DR GO; GO:0005576; C:extracellular region; IEA:InterPro.
DR GO; GO:0051715; P:cytolysis in another organism; IEA:InterPro.
DR InterPro; IPR003963; Bi-component_toxin_staph.
DR InterPro; IPR016183; Leukocidin/Hemolysin_toxin.
DR InterPro; IPR036435; Leukocidin/porin_MspA_sf.
DR Pfam; PF07968; Leukocidin; 1.
DR PRINTS; PR01468; BICOMPNTOXIN.
DR SUPFAM; SSF56959; SSF56959; 1.
PE 3: Inferred from homology;
KW Signal.
FT SIGNAL 1..27
FT /evidence="ECO:0000255"
FT CHAIN 28..351
FT /note="Uncharacterized leukocidin-like protein 2"
FT /id="PRO_0000298647"
FT REGION 27..71
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 33..71
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 351 AA; 40434 MW; B562DA10D8C9DE00 CRC64;
MKNKKRVLIA SSLSCAILLL SAATTQANSA HKDSQDQNKK EHVDKSQQKD KRNVTNKDKN
STAPDDIGKN GKITKRTETV YDEKTNILQN LQFDFIDDPT YDKNVLLVKK QGSIHSNLKF
ESHKEEKNSN WLKYPSEYHV DFQVKRNRKT EILDQLPKNK ISTAKVDSTF SYSSGGKFDS
TKGIGRTSSN SYSKTISYNQ QNYDTIASGK NNNWHVHWSV IANDLKYGGE VKNRNDELLF
YRNTRIATVE NPELSFASKY RYPALVRSGF NPEFLTYLSN EKSNEKTQFE VTYTRNQDIL
KNRPGIHYAP PILEKNKDGQ RLIVTYEVDW KNKTVKVVDK YSDDNKPYKE G