ID   LUKL2_STAAB             Reviewed;         351 AA.
AC   Q2YU83;
DT   21-AUG-2007, integrated into UniProtKB/Swiss-Prot.
DT   20-DEC-2005, sequence version 1.
DT   25-MAY-2022, entry version 84.
DE   RecName: Full=Uncharacterized leukocidin-like protein 2;
DE   Flags: Precursor;
GN   OrderedLocusNames=SAB1876c;
OS   Staphylococcus aureus (strain bovine RF122 / ET3-1).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=273036;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=bovine RF122 / ET3-1;
RX   PubMed=17971880; DOI=10.1371/journal.pone.0001120;
RA   Herron-Olson L., Fitzgerald J.R., Musser J.M., Kapur V.;
RT   "Molecular correlates of host specialization in Staphylococcus aureus.";
RL   PLoS ONE 2:E1120-E1120(2007).
CC   -!- SIMILARITY: Belongs to the aerolysin family. {ECO:0000305}.
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DR   EMBL; AJ938182; CAI81565.1; -; Genomic_DNA.
DR   RefSeq; WP_000791410.1; NC_007622.1.
DR   AlphaFoldDB; Q2YU83; -.
DR   SMR; Q2YU83; -.
DR   KEGG; sab:SAB1876c; -.
DR   HOGENOM; CLU_865755_0_0_9; -.
DR   OMA; HWSVVAN; -.
DR   GO; GO:0005576; C:extracellular region; IEA:InterPro.
DR   GO; GO:0051715; P:cytolysis in another organism; IEA:InterPro.
DR   InterPro; IPR003963; Bi-component_toxin_staph.
DR   InterPro; IPR016183; Leukocidin/Hemolysin_toxin.
DR   InterPro; IPR036435; Leukocidin/porin_MspA_sf.
DR   Pfam; PF07968; Leukocidin; 1.
DR   PRINTS; PR01468; BICOMPNTOXIN.
DR   SUPFAM; SSF56959; SSF56959; 1.
PE   3: Inferred from homology;
KW   Signal.
FT   SIGNAL          1..27
FT                   /evidence="ECO:0000255"
FT   CHAIN           28..351
FT                   /note="Uncharacterized leukocidin-like protein 2"
FT                   /id="PRO_0000298639"
FT   REGION          29..71
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        33..71
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   351 AA;  40502 MW;  792058A7D5CD86A4 CRC64;
     MKNKKRVLIA SSLSCAILLL SAATTQANSA HKDSQDQNKK EHVDKSQQKD KRNVTNKDKN
     STVPDDIGKN GKITKRTETV YDEKTNILQN LQFDFIDDPT YDKNVLLVKK QGSIHSNLKF
     ESHKEEKNSN WLKYPSEYHV DFQVKRNRKT EILDQLPKNK ISTAKVDSTF SYSSGGKFDS
     TKGIGRTSSN SYSKTISYNQ QKYDTIAIGK NNNWHVHWSV IANDLKYGGE VKNRNDELLF
     YRNTRIATVE NPELSFASKY RYPALVRSGF NPEFLTYLSN EKSNEKTQFE VTYTRNQDIL
     KNRPGIHYAP PILEKNKDGQ RLIVTYEVDW KNKTVKVVDK YSDDNKPYKE G