ID   LUKL2_STAAM             Reviewed;         351 AA.
AC   Q931I5;
DT   21-AUG-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-2001, sequence version 1.
DT   03-AUG-2022, entry version 99.
DE   RecName: Full=Uncharacterized leukocidin-like protein 2;
DE   Flags: Precursor;
GN   OrderedLocusNames=SAV2005;
OS   Staphylococcus aureus (strain Mu50 / ATCC 700699).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=158878;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Mu50 / ATCC 700699;
RX   PubMed=11418146; DOI=10.1016/s0140-6736(00)04403-2;
RA   Kuroda M., Ohta T., Uchiyama I., Baba T., Yuzawa H., Kobayashi I., Cui L.,
RA   Oguchi A., Aoki K., Nagai Y., Lian J.-Q., Ito T., Kanamori M.,
RA   Matsumaru H., Maruyama A., Murakami H., Hosoyama A., Mizutani-Ui Y.,
RA   Takahashi N.K., Sawano T., Inoue R., Kaito C., Sekimizu K., Hirakawa H.,
RA   Kuhara S., Goto S., Yabuzaki J., Kanehisa M., Yamashita A., Oshima K.,
RA   Furuya K., Yoshino C., Shiba T., Hattori M., Ogasawara N., Hayashi H.,
RA   Hiramatsu K.;
RT   "Whole genome sequencing of meticillin-resistant Staphylococcus aureus.";
RL   Lancet 357:1225-1240(2001).
CC   -!- SIMILARITY: Belongs to the aerolysin family. {ECO:0000305}.
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DR   EMBL; BA000017; BAB58167.1; -; Genomic_DNA.
DR   RefSeq; WP_000791413.1; NC_002758.2.
DR   AlphaFoldDB; Q931I5; -.
DR   SMR; Q931I5; -.
DR   World-2DPAGE; 0002:Q931I5; -.
DR   PaxDb; Q931I5; -.
DR   EnsemblBacteria; BAB58167; BAB58167; SAV2005.
DR   KEGG; sav:SAV2005; -.
DR   HOGENOM; CLU_865755_0_0_9; -.
DR   OMA; HWSVVAN; -.
DR   PhylomeDB; Q931I5; -.
DR   BioCyc; SAUR158878:SAV_RS10960-MON; -.
DR   Proteomes; UP000002481; Chromosome.
DR   GO; GO:0005576; C:extracellular region; IEA:InterPro.
DR   GO; GO:0051715; P:cytolysis in another organism; IEA:InterPro.
DR   InterPro; IPR003963; Bi-component_toxin_staph.
DR   InterPro; IPR016183; Leukocidin/Hemolysin_toxin.
DR   InterPro; IPR036435; Leukocidin/porin_MspA_sf.
DR   Pfam; PF07968; Leukocidin; 1.
DR   PRINTS; PR01468; BICOMPNTOXIN.
DR   SUPFAM; SSF56959; SSF56959; 1.
PE   3: Inferred from homology;
KW   Signal.
FT   SIGNAL          1..27
FT                   /evidence="ECO:0000255"
FT   CHAIN           28..351
FT                   /note="Uncharacterized leukocidin-like protein 2"
FT                   /id="PRO_0000298643"
FT   REGION          28..71
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        33..71
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   351 AA;  40452 MW;  B14C4DFD858BBA2B CRC64;
     MKNKKRVLIA SSLSCAILLL SAATTQANSA HKDSQDQNKK EHVDKSQQKD KRNVTNKDKN
     STVPDDIGKN GKITKRTETV YDEKTNILQN LQFDFIDDPT YDKNVLLVKK QGSIHSNLKF
     ESHKEEKNSN WLKYPSEYHV DFQVKRNRKT EILDQLPKNK ISTAKVDSTF SYSSGGKFDS
     TKGIGRTSSN SYSKTISYNQ QNYDTIASGK NNNWHVHWSV IANDLKYGGE VKNRNDELLF
     YRNTRIATVE NPELSFASKY RYPALVRSGF NPEFLTYLSN EKSNEKTQFE VTYTRNQDIL
     KNRPGIHYAP SILEKNKDGQ RLIVTYEVDW KNKTVKVVDK YSDDNKPYKE G