LUXD_PHOLL
ID LUXD_PHOLL Reviewed; 307 AA.
AC Q7N576;
DT 10-MAY-2004, integrated into UniProtKB/Swiss-Prot.
DT 15-DEC-2003, sequence version 1.
DT 03-AUG-2022, entry version 95.
DE RecName: Full=Acyl transferase {ECO:0000255|HAMAP-Rule:MF_00774};
DE Short=ACT {ECO:0000255|HAMAP-Rule:MF_00774};
DE EC=2.3.1.- {ECO:0000255|HAMAP-Rule:MF_00774};
DE AltName: Full=C14ACP-TE {ECO:0000255|HAMAP-Rule:MF_00774};
DE AltName: Full=Myristoyl-ACP-specific thioesterase {ECO:0000255|HAMAP-Rule:MF_00774};
GN Name=luxD {ECO:0000255|HAMAP-Rule:MF_00774}; OrderedLocusNames=plu2080;
OS Photorhabdus laumondii subsp. laumondii (strain DSM 15139 / CIP 105565 /
OS TT01).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Morganellaceae; Photorhabdus.
OX NCBI_TaxID=243265;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 15139 / CIP 105565 / TT01;
RX PubMed=14528314; DOI=10.1038/nbt886;
RA Duchaud E., Rusniok C., Frangeul L., Buchrieser C., Givaudan A.,
RA Taourit S., Bocs S., Boursaux-Eude C., Chandler M., Charles J.-F.,
RA Dassa E., Derose R., Derzelle S., Freyssinet G., Gaudriault S., Medigue C.,
RA Lanois A., Powell K., Siguier P., Vincent R., Wingate V., Zouine M.,
RA Glaser P., Boemare N., Danchin A., Kunst F.;
RT "The genome sequence of the entomopathogenic bacterium Photorhabdus
RT luminescens.";
RL Nat. Biotechnol. 21:1307-1313(2003).
CC -!- FUNCTION: Acyl transferase is part of the fatty acid reductase system
CC required for aldehyde biosynthesis; it produces fatty acids for the
CC luminescent reaction. {ECO:0000255|HAMAP-Rule:MF_00774}.
CC -!- PATHWAY: Lipid metabolism; fatty acid reduction for biolumincescence.
CC {ECO:0000255|HAMAP-Rule:MF_00774}.
CC -!- SIMILARITY: Belongs to the LuxD family. {ECO:0000255|HAMAP-
CC Rule:MF_00774}.
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DR EMBL; BX571866; CAE14373.1; -; Genomic_DNA.
DR RefSeq; WP_011146335.1; NC_005126.1.
DR AlphaFoldDB; Q7N576; -.
DR SMR; Q7N576; -.
DR STRING; 243265.plu2080; -.
DR ESTHER; pholu-LUXD2; Thioesterase_acyl-transferase.
DR EnsemblBacteria; CAE14373; CAE14373; plu2080.
DR GeneID; 24166559; -.
DR KEGG; plu:plu2080; -.
DR eggNOG; COG1073; Bacteria.
DR HOGENOM; CLU_882365_0_0_6; -.
DR OMA; FARRMDH; -.
DR OrthoDB; 631878at2; -.
DR BioCyc; PLUM243265:PLU_RS10390-MON; -.
DR UniPathway; UPA00569; -.
DR Proteomes; UP000002514; Chromosome.
DR GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:UniProtKB-UniRule.
DR GO; GO:0008218; P:bioluminescence; IEA:UniProtKB-UniRule.
DR GO; GO:0006631; P:fatty acid metabolic process; IEA:InterPro.
DR Gene3D; 3.40.50.1820; -; 1.
DR HAMAP; MF_00774; LuxD; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR003157; LuxD.
DR Pfam; PF02273; Acyl_transf_2; 1.
DR PIRSF; PIRSF009416; LuxD; 1.
DR SUPFAM; SSF53474; SSF53474; 1.
PE 3: Inferred from homology;
KW Acyltransferase; Luminescence; Reference proteome; Transferase.
FT CHAIN 1..307
FT /note="Acyl transferase"
FT /id="PRO_0000220189"
FT ACT_SITE 116
FT /note="Charge relay system"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00774"
FT ACT_SITE 213
FT /note="Charge relay system"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00774"
FT ACT_SITE 243
FT /note="Charge relay system"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00774"
SQ SEQUENCE 307 AA; 34732 MW; C9CADB74038F8AC7 CRC64;
MENKSKYKTI DHVLCVEGNK KIHVWETLPE ENSPKRKNTI IIASGFARRM DHFAGLAEYL
SRNGFHVIRY DSLHHVGLSS GTIDEFTMSI GKQSLLAVVD WLNTRKINNR GILASSLSAR
IVYASLSEIN VSFLITAVGV VNLRYTLERA LGFDYLSLPI NELPNNLDFE GHKLGAEVFA
RDCLDFGWED LTSTINSMMY LDIPFIAFTA NNDNWVKQDE VITLLSNIRS NRCKIYSLLG
SSHDLGENLV VLRNFYQSVT KAAIAMDNDR LDIDVDIIEP SFEHLTIATV NERRMKIEIE
NQAISLS
