ID   LUXG_PHOLE              Reviewed;         234 AA.
AC   P29237;
DT   01-DEC-1992, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-1992, sequence version 1.
DT   03-AUG-2022, entry version 73.
DE   RecName: Full=Probable flavin reductase;
DE            EC=1.-.-.-;
GN   Name=luxG;
OS   Photobacterium leiognathi.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Photobacterium.
OX   NCBI_TaxID=553611;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 25521 / DSM 21260 / CIP 66.5 / NCIMB 2193 / L1;
RX   PubMed=1915359; DOI=10.1111/j.1432-1033.1991.tb16269.x;
RA   Lee C.Y., Szittner R.B., Meighen E.A.;
RT   "The lux genes of the luminous bacterial symbiont, Photobacterium
RT   leiognathi, of the ponyfish. Nucleotide sequence, difference in gene
RT   organization, and high expression in mutant Escherichia coli.";
RL   Eur. J. Biochem. 201:161-167(1991).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 198-234.
RC   STRAIN=ATCC 25521 / DSM 21260 / CIP 66.5 / NCIMB 2193 / L1;
RX   PubMed=1339274; DOI=10.1016/0006-291x(92)90802-r;
RA   Lee C.Y., Meighen E.A.;
RT   "The lux genes in Photobacterium leiognathi are closely linked with genes
RT   corresponding in sequence to riboflavin synthesis genes.";
RL   Biochem. Biophys. Res. Commun. 186:690-697(1992).
CC   -!- FUNCTION: Probable flavin reductase in the luminescent systems of
CC       different marine bacteria.
CC   -!- SIMILARITY: Belongs to the Fre/LuxG FAD/NAD(P) flavoprotein
CC       oxidoreductase family. {ECO:0000305}.
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DR   EMBL; M63594; AAA25621.1; -; Genomic_DNA.
DR   EMBL; M90094; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   PIR; S17956; S17956.
DR   RefSeq; WP_023934908.1; NZ_PYOJ01000031.1.
DR   AlphaFoldDB; P29237; -.
DR   SMR; P29237; -.
DR   OrthoDB; 1834577at2; -.
DR   BRENDA; 1.5.1.42; 4778.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008218; P:bioluminescence; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.80; -; 1.
DR   InterPro; IPR039261; FNR_nucleotide-bd.
DR   InterPro; IPR001433; OxRdtase_FAD/NAD-bd.
DR   InterPro; IPR017938; Riboflavin_synthase-like_b-brl.
DR   Pfam; PF00175; NAD_binding_1; 1.
DR   SUPFAM; SSF52343; SSF52343; 1.
DR   SUPFAM; SSF63380; SSF63380; 1.
PE   3: Inferred from homology;
KW   FAD; Flavoprotein; Luminescence; Oxidoreductase.
FT   CHAIN           1..234
FT                   /note="Probable flavin reductase"
FT                   /id="PRO_0000068141"
FT   BINDING         112..116
FT                   /ligand="pyridine"
FT                   /ligand_id="ChEBI:CHEBI:16227"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   234 AA;  26217 MW;  BAC2B034C80A46DA CRC64;
     MIFNCKVKKV EASDSHIYKV FIKPDKCFDF KAGQYVIVYL NGKNLPFSIA NCPTCNELLE
     LHVGGSVKES AIEAISHFIN AFIYQKEFTI DAPHGDAWLR DESQSPLLLI AGGTGLSYIN
     SILSCCISKQ LSQPIYLYWG VNNCNLLYAD QQLKTLAAQY RNINYIPVVE NLNTDWQGKI
     GNVIDAVIED FSDLSDFDIY VCGPFGMSRT AKDILISQKK ANIGKMYSDA FSYT