ID   LUXP_VIBPA              Reviewed;         365 AA.
AC   Q87GU4;
DT   19-JUL-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   03-AUG-2022, entry version 84.
DE   RecName: Full=Autoinducer 2-binding periplasmic protein LuxP;
DE   Flags: Precursor;
GN   Name=luxP; OrderedLocusNames=VPA1221;
OS   Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Vibrio.
OX   NCBI_TaxID=223926;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RIMD 2210633;
RX   PubMed=12620739; DOI=10.1016/s0140-6736(03)12659-1;
RA   Makino K., Oshima K., Kurokawa K., Yokoyama K., Uda T., Tagomori K.,
RA   Iijima Y., Najima M., Nakano M., Yamashita A., Kubota Y., Kimura S.,
RA   Yasunaga T., Honda T., Shinagawa H., Hattori M., Iida T.;
RT   "Genome sequence of Vibrio parahaemolyticus: a pathogenic mechanism
RT   distinct from that of V. cholerae.";
RL   Lancet 361:743-749(2003).
CC   -!- FUNCTION: Binds to the signaling molecule autoinducer 2 (AI-2), a
CC       furanosyl borate diester, (3a-methyl-5,6-dihydrofuro-
CC       [2,3d][1,3,2]dioxaborole-2,2,6,6a-tetraol). This complex then interacts
CC       with the LuxQ sensor protein (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the bacterial solute-binding protein 2 family.
CC       {ECO:0000305}.
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DR   EMBL; BA000032; BAC62564.1; -; Genomic_DNA.
DR   RefSeq; NP_800731.1; NC_004605.1.
DR   RefSeq; WP_005463467.1; NC_004605.1.
DR   AlphaFoldDB; Q87GU4; -.
DR   SMR; Q87GU4; -.
DR   STRING; 223926.28809589; -.
DR   EnsemblBacteria; BAC62564; BAC62564; BAC62564.
DR   GeneID; 1191917; -.
DR   KEGG; vpa:VPA1221; -.
DR   PATRIC; fig|223926.6.peg.4149; -.
DR   eggNOG; COG1879; Bacteria.
DR   HOGENOM; CLU_064743_1_0_6; -.
DR   OMA; DDTGIAM; -.
DR   Proteomes; UP000002493; Chromosome 2.
DR   GO; GO:0030288; C:outer membrane-bounded periplasmic space; IEA:UniProt.
DR   InterPro; IPR028082; Peripla_BP_I.
DR   InterPro; IPR025997; SBP_2_dom.
DR   Pfam; PF13407; Peripla_BP_4; 1.
DR   SUPFAM; SSF53822; SSF53822; 1.
PE   3: Inferred from homology;
KW   Periplasm; Reference proteome; Signal.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000255"
FT   CHAIN           22..365
FT                   /note="Autoinducer 2-binding periplasmic protein LuxP"
FT                   /id="PRO_0000031727"
SQ   SEQUENCE   365 AA;  41340 MW;  24B6D1192B0D6D84 CRC64;
     MNKALVLSLI SIAGMSPASQ ASQVLNGYWA YQEFLNEFPE QKHLTDALAA AVRDDPVPIA
     PEKRHPLKIS VVYPGQQISD YWIRNIDAFE KRLDKLNIDY QINQVFTRPN ADIKQQSLSL
     MEALKSNSDY LIFTLDTTRH RKFVEHVLDS TKTKLILQNI TTPVREWETR QPFMYVGFDH
     AEGSRELAVE FGKQFPKNTH YSVLYFSEGY ISDIRGNTFI HQVNQDSQFE LQSAYYTKAT
     KQSGYEAAKA SLKKYPDVEF IYACSTDVAL GAVEALSELG REDVMINGWG GGSAELDAIL
     KGELDITVMR MNDDTGIAMA EAIKWDLEGK PVPTVYSGDF EVVTKSDSPE RIEALRKRAF
     RYSDN