ID   LUZP1_RAT               Reviewed;        1051 AA.
AC   Q9ESV1;
DT   16-MAY-2006, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2001, sequence version 1.
DT   25-MAY-2022, entry version 86.
DE   RecName: Full=Leucine zipper protein 1;
DE   AltName: Full=Leucine zipper motif-containing protein;
GN   Name=Luzp1; Synonyms=Luzp;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA], SUBCELLULAR LOCATION, AND TISSUE SPECIFICITY.
RC   TISSUE=Brain;
RX   PubMed=8812416; DOI=10.1006/geno.1996.0425;
RA   Sun D.-S., Chang A.C., Jenkins N.A., Gilbert D.J., Copeland N.G.,
RA   Chang N.-C.A.;
RT   "Identification, molecular characterization, and chromosomal localization
RT   of the cDNA encoding a novel leucine zipper motif-containing protein.";
RL   Genomics 36:54-62(1996).
RN   [2]
RP   PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-261; SER-612 AND SER-660, AND
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=22673903; DOI=10.1038/ncomms1871;
RA   Lundby A., Secher A., Lage K., Nordsborg N.B., Dmytriyev A., Lundby C.,
RA   Olsen J.V.;
RT   "Quantitative maps of protein phosphorylation sites across 14 different rat
RT   organs and tissues.";
RL   Nat. Commun. 3:876-876(2012).
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:8812416}. Note=Also
CC       detected in soma and dendrites of neurons.
CC   -!- TISSUE SPECIFICITY: Expressed in cerebral cortex, cerebellum,
CC       hippocampus and brain stem. {ECO:0000269|PubMed:8812416}.
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DR   EMBL; AF181259; AAG02142.1; -; mRNA.
DR   AlphaFoldDB; Q9ESV1; -.
DR   SMR; Q9ESV1; -.
DR   STRING; 10116.ENSRNOP00000016514; -.
DR   iPTMnet; Q9ESV1; -.
DR   PhosphoSitePlus; Q9ESV1; -.
DR   PaxDb; Q9ESV1; -.
DR   PeptideAtlas; Q9ESV1; -.
DR   PRIDE; Q9ESV1; -.
DR   RGD; 61839; Luzp1.
DR   eggNOG; ENOG502QV81; Eukaryota.
DR   InParanoid; Q9ESV1; -.
DR   PRO; PR:Q9ESV1; -.
DR   Proteomes; UP000002494; Unplaced.
DR   GO; GO:0005634; C:nucleus; ISO:RGD.
DR   GO; GO:0060840; P:artery development; ISO:RGD.
DR   GO; GO:0021503; P:neural fold bending; ISO:RGD.
DR   GO; GO:0003281; P:ventricular septum development; ISO:RGD.
DR   InterPro; IPR026734; Luzp1.
DR   PANTHER; PTHR23166:SF7; PTHR23166:SF7; 1.
PE   1: Evidence at protein level;
KW   Acetylation; Coiled coil; Nucleus; Phosphoprotein; Reference proteome.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000250|UniProtKB:Q86V48"
FT   CHAIN           2..1051
FT                   /note="Leucine zipper protein 1"
FT                   /id="PRO_0000234552"
FT   REGION          247..293
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          374..401
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          432..554
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          569..601
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          675..727
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          789..837
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          929..1000
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          11..354
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        256..293
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        789..805
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        816..837
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        945..962
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        984..1000
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         2
FT                   /note="N-acetylalanine"
FT                   /evidence="ECO:0000250|UniProtKB:Q86V48"
FT   MOD_RES         256
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q86V48"
FT   MOD_RES         261
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0007744|PubMed:22673903"
FT   MOD_RES         395
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q86V48"
FT   MOD_RES         513
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q86V48"
FT   MOD_RES         571
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q86V48"
FT   MOD_RES         575
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q86V48"
FT   MOD_RES         612
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0007744|PubMed:22673903"
FT   MOD_RES         660
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0007744|PubMed:22673903"
FT   MOD_RES         680
FT                   /note="Phosphothreonine"
FT                   /evidence="ECO:0000250|UniProtKB:Q86V48"
FT   MOD_RES         691
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q86V48"
FT   MOD_RES         746
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q86V48"
FT   MOD_RES         906
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q86V48"
FT   MOD_RES         957
FT                   /note="Phosphothreonine"
FT                   /evidence="ECO:0000250|UniProtKB:Q86V48"
FT   MOD_RES         993
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q86V48"
SQ   SEQUENCE   1051 AA;  117176 MW;  FE1F3D7100326843 CRC64;
     MADIANYKDA ASNRHLRFKL QSLSRRLDEL EEATKNLQKA EDELLDLQDK VIQAEGSNSS
     MLAEIEVLRQ RVLKIEGKDE EIKRAEDLCH TMKEKLEEEE NLTRELKSEI DRLQKRMADL
     EKLEEALSRS KNECSQLCLS LNEERNLTKK ISSELEMLRV KVKELESSED RLEKTEQSLV
     SELEKLKSLT LSFVNERKYL NEKEKENEKL IKELTQKLEQ NKKINRDHMR NASTFLERND
     LRIEDGISST LPSKESRRKG SLDYLKQVEN ETRDKSENEK NRNQEDNKVK DLNQEIEKLK
     TQIKHFESLE EELKKMRAKN NDLQDNYLTE LNKNRSLASQ LEEVKLQVKK QKELGNGDIE
     GEDAFLLGRG RHERTKLKGH GGEVSVSKHT SREQSPQHKR ERLRNRGFAL NDEHCSLSNK
     QVSSPAFTNK RAAKASNMGV GPDSGTQETK RTEDRLAPGS SQSEGKKGRE QPSVLSRYPP
     AAQDHTKVWR GNPKPGTESG LKGKVEKTTR TFSDSAHGSV PNDVVGKGDK TSDFSSEAHC
     GKRGQVPGHA SQVTQVAESG CSKAIGALAS SQRASSEGLS KGKKAANGLE TDANFPHSKA
     PILSKYPYSS RSQENILQGF SVPNKEGVDH SVAVVMEDSS QHEALRCRVI KSSGREKPDS
     DDDLDIESLV TAKLVNTTIT PEPEPKLQPN SREKVKSRGG TRTPLFENDK NAAVENDSAK
     SMRSSSNAVE FPDANCAGVK NQRPFSPREA LRSRAIIKPV IIDKDVKKIM GGSGTEVVLE
     KQKSTPKSVT SKVTSSITIY PSDSSGPRAV PTEAPRERHT STSNIQVGPP ELTSVSNHIS
     SPLELSIHKH DITLQLTEAE RVGDGSPKNR AETVVSRSSI LIKPSDSVER NSHAFPAETI
     RWKSHSTSSE VASSDTRHIT VRNAWKSKRD LKCSEDPPTR IGRNVEATNA YTQRSSTDFL
     ELEQPRSHPP EQGTRKVGNS GDAPELSSRR TQSSLTASEV LTRRNRIGDA VTAASWNHSS
     NVVSLTFLPS ALICLTEDLG NTEGWEMLNL R