ID   LV1A_MOUSE              Reviewed;         117 AA.
AC   P01723;
DT   21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 2.
DT   03-AUG-2022, entry version 137.
DE   RecName: Full=Ig lambda-1 chain V region;
DE   Flags: Precursor;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=103630; DOI=10.1016/0092-8674(78)90041-7;
RA   Bernard O., Hozumi N., Tonegawa S.;
RT   "Sequences of mouse immunoglobulin light chain genes before and after
RT   somatic changes.";
RL   Cell 15:1133-1144(1978).
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DR   EMBL; V00811; CAA24193.1; -; Genomic_DNA.
DR   PIR; A01994; L1MSV.
DR   PIR; PH1090; PH1090.
DR   PDB; 1P4B; X-ray; 2.35 A; L=22-117.
DR   PDB; 1P4I; X-ray; 2.80 A; L=22-117.
DR   PDB; 1Q0X; X-ray; 1.60 A; L=22-117.
DR   PDB; 1SM3; X-ray; 1.95 A; L=23-117.
DR   PDBsum; 1P4B; -.
DR   PDBsum; 1P4I; -.
DR   PDBsum; 1Q0X; -.
DR   PDBsum; 1SM3; -.
DR   AlphaFoldDB; P01723; -.
DR   SMR; P01723; -.
DR   IntAct; P01723; 1.
DR   MaxQB; P01723; -.
DR   PRIDE; P01723; -.
DR   EvolutionaryTrace; P01723; -.
DR   Proteomes; UP000000589; Unplaced.
DR   RNAct; P01723; protein.
DR   GO; GO:0005615; C:extracellular space; IBA:GO_Central.
DR   GO; GO:0019814; C:immunoglobulin complex; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; TAS:Reactome.
DR   GO; GO:0002250; P:adaptive immune response; IEA:UniProtKB-KW.
DR   GO; GO:0006955; P:immune response; IBA:GO_Central.
DR   Gene3D; 2.60.40.10; -; 1.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR003599; Ig_sub.
DR   InterPro; IPR013106; Ig_V-set.
DR   Pfam; PF07686; V-set; 1.
DR   SMART; SM00409; IG; 1.
DR   SMART; SM00406; IGv; 1.
DR   SUPFAM; SSF48726; SSF48726; 1.
DR   PROSITE; PS50835; IG_LIKE; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Adaptive immunity; Immunity; Immunoglobulin;
KW   Pyrrolidone carboxylic acid; Reference proteome; Signal.
FT   SIGNAL          1..20
FT   CHAIN           21..117
FT                   /note="Ig lambda-1 chain V region"
FT                   /id="PRO_0000015201"
FT   DOMAIN          21..>117
FT                   /note="Ig-like"
FT   MOD_RES         21
FT                   /note="Pyrrolidone carboxylic acid"
FT                   /evidence="ECO:0000250|UniProtKB:P01724"
FT   NON_TER         117
FT   STRAND          24..26
FT                   /evidence="ECO:0007829|PDB:1Q0X"
FT   STRAND          28..32
FT                   /evidence="ECO:0007829|PDB:1Q0X"
FT   STRAND          38..47
FT                   /evidence="ECO:0007829|PDB:1Q0X"
FT   HELIX           51..53
FT                   /evidence="ECO:0007829|PDB:1Q0X"
FT   STRAND          56..61
FT                   /evidence="ECO:0007829|PDB:1Q0X"
FT   TURN            62..64
FT                   /evidence="ECO:0007829|PDB:1Q0X"
FT   STRAND          65..71
FT                   /evidence="ECO:0007829|PDB:1Q0X"
FT   TURN            72..74
FT                   /evidence="ECO:0007829|PDB:1Q0X"
FT   STRAND          84..89
FT                   /evidence="ECO:0007829|PDB:1Q0X"
FT   STRAND          92..99
FT                   /evidence="ECO:0007829|PDB:1Q0X"
FT   HELIX           102..104
FT                   /evidence="ECO:0007829|PDB:1Q0X"
FT   STRAND          106..113
FT                   /evidence="ECO:0007829|PDB:1Q0X"
SQ   SEQUENCE   117 AA;  12222 MW;  36F3C5601C54B55A CRC64;
     MAWISLILSL LALSSGGAIS QAVVTQESAL TTSPGETVTL TCRSSTGAVT TSNYANWVQE
     KPDHLFTGLI GGTNNRAPGV PARFSGSLIG DKAALTITGA QTEDEAIYFC ALWYSNH