LV1E_MOUSE
ID LV1E_MOUSE Reviewed; 129 AA.
AC P01727;
DT 21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT 21-JUL-1986, sequence version 1.
DT 25-MAY-2022, entry version 113.
DE RecName: Full=Ig lambda-1 chain V region S43;
DE Flags: Precursor;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE.
RX PubMed=6283385; DOI=10.1038/298380a0;
RA Bothwell A.L.M., Paskind M., Reth M., Imanishi-Kari T., Rajewsky K.,
RA Baltimore D.;
RT "Somatic variants of murine immunoglobulin lambda light chains.";
RL Nature 298:380-382(1982).
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DR PIR; PH1089; PH1089.
DR PDB; 5A2I; X-ray; 1.88 A; H=20-129.
DR PDB; 5A2J; X-ray; 1.65 A; H=20-116.
DR PDB; 5A2K; X-ray; 1.70 A; H=20-129.
DR PDB; 5A2L; X-ray; 1.79 A; H=20-129.
DR PDB; 5N7B; X-ray; 1.70 A; H=19-129.
DR PDBsum; 5A2I; -.
DR PDBsum; 5A2J; -.
DR PDBsum; 5A2K; -.
DR PDBsum; 5A2L; -.
DR PDBsum; 5N7B; -.
DR AlphaFoldDB; P01727; -.
DR SMR; P01727; -.
DR MINT; P01727; -.
DR MaxQB; P01727; -.
DR PRIDE; P01727; -.
DR Proteomes; UP000000589; Unplaced.
DR RNAct; P01727; protein.
DR GO; GO:0005615; C:extracellular space; IBA:GO_Central.
DR GO; GO:0019814; C:immunoglobulin complex; IEA:UniProtKB-KW.
DR GO; GO:0002250; P:adaptive immune response; IEA:UniProtKB-KW.
DR GO; GO:0006955; P:immune response; IBA:GO_Central.
DR Gene3D; 2.60.40.10; -; 1.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR013106; Ig_V-set.
DR Pfam; PF07686; V-set; 1.
DR SMART; SM00409; IG; 1.
DR SMART; SM00406; IGv; 1.
DR SUPFAM; SSF48726; SSF48726; 1.
DR PROSITE; PS50835; IG_LIKE; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Adaptive immunity; Immunity; Immunoglobulin;
KW Pyrrolidone carboxylic acid; Reference proteome; Signal.
FT SIGNAL 1..19
FT CHAIN 20..129
FT /note="Ig lambda-1 chain V region S43"
FT /id="PRO_0000015204"
FT DOMAIN 20..125
FT /note="Ig-like"
FT MOD_RES 20
FT /note="Pyrrolidone carboxylic acid"
FT /evidence="ECO:0000250|UniProtKB:P01724"
FT NON_TER 129
FT STRAND 23..25
FT /evidence="ECO:0007829|PDB:5A2J"
FT STRAND 27..31
FT /evidence="ECO:0007829|PDB:5A2J"
FT STRAND 36..43
FT /evidence="ECO:0007829|PDB:5A2J"
FT HELIX 50..52
FT /evidence="ECO:0007829|PDB:5A2J"
FT STRAND 55..60
FT /evidence="ECO:0007829|PDB:5A2J"
FT TURN 61..63
FT /evidence="ECO:0007829|PDB:5A2J"
FT STRAND 64..70
FT /evidence="ECO:0007829|PDB:5A2J"
FT TURN 71..73
FT /evidence="ECO:0007829|PDB:5A2J"
FT STRAND 83..88
FT /evidence="ECO:0007829|PDB:5A2J"
FT STRAND 91..98
FT /evidence="ECO:0007829|PDB:5A2J"
FT HELIX 101..103
FT /evidence="ECO:0007829|PDB:5A2J"
FT STRAND 105..112
FT /evidence="ECO:0007829|PDB:5A2J"
FT STRAND 117..119
FT /evidence="ECO:0007829|PDB:5A2J"
FT STRAND 123..127
FT /evidence="ECO:0007829|PDB:5A2J"
SQ SEQUENCE 129 AA; 13529 MW; 84E54E7DD5791345 CRC64;
MAWISLILSL LALSSGAISQ AVVTQESALT TSPGETVTLT CRSSTGAVTT SNYANWVQEK
PDHLFTGLIG GTNNRAPGVP ARFSGSLIGD KAALTITGTQ TEDEAMYFCA LWYSNHWVFG
GGTKLTVLG
