ID   LV2A_MOUSE              Reviewed;         117 AA.
AC   P01728;
DT   21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT   21-JUL-1986, sequence version 1.
DT   03-AUG-2022, entry version 120.
DE   RecName: Full=Ig lambda-2 chain V region;
DE   Flags: Precursor;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=418414; DOI=10.1073/pnas.75.3.1485;
RA   Tonegawa S., Maxam A.M., Tizard R., Bernard O., Gilbert W.;
RT   "Sequence of a mouse germ-line gene for a variable region of an
RT   immunoglobulin light chain.";
RL   Proc. Natl. Acad. Sci. U.S.A. 75:1485-1489(1978).
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DR   EMBL; J00599; AAA39167.1; -; Genomic_DNA.
DR   EMBL; V00815; CAA24196.2; -; Genomic_DNA.
DR   EMBL; X58412; CAA41313.1; -; Genomic_DNA.
DR   EMBL; X58418; CAA41318.1; -; Genomic_DNA.
DR   EMBL; X58423; CAA41323.1; -; Genomic_DNA.
DR   EMBL; X58424; CAA41324.1; -; Genomic_DNA.
DR   PIR; A01996; L2MSWE.
DR   PIR; PL0192; PL0192.
DR   AlphaFoldDB; P01728; -.
DR   SMR; P01728; -.
DR   MaxQB; P01728; -.
DR   PRIDE; P01728; -.
DR   Ensembl; ENSMUST00000197518; ENSMUSP00000142646; ENSMUSG00000076940.
DR   VEuPathDB; HostDB:ENSMUSG00000076940; -.
DR   GeneTree; ENSGT00940000163781; -.
DR   HOGENOM; CLU_077975_4_0_1; -.
DR   OMA; QQKPYQR; -.
DR   Proteomes; UP000000589; Chromosome 16.
DR   RNAct; P01728; protein.
DR   Bgee; ENSMUSG00000076940; Expressed in spleen and 23 other tissues.
DR   ExpressionAtlas; P01728; baseline and differential.
DR   GO; GO:0005615; C:extracellular space; IBA:GO_Central.
DR   GO; GO:0019814; C:immunoglobulin complex; IEA:UniProtKB-KW.
DR   GO; GO:0002250; P:adaptive immune response; IEA:UniProtKB-KW.
DR   GO; GO:0006955; P:immune response; IBA:GO_Central.
DR   Gene3D; 2.60.40.10; -; 1.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR013106; Ig_V-set.
DR   Pfam; PF07686; V-set; 1.
DR   SMART; SM00406; IGv; 1.
DR   SUPFAM; SSF48726; SSF48726; 1.
DR   PROSITE; PS50835; IG_LIKE; 1.
PE   3: Inferred from homology;
KW   Adaptive immunity; Immunity; Immunoglobulin; Pyrrolidone carboxylic acid;
KW   Reference proteome; Signal.
FT   SIGNAL          1..19
FT   CHAIN           20..117
FT                   /note="Ig lambda-2 chain V region"
FT                   /id="PRO_0000015205"
FT   DOMAIN          20..>117
FT                   /note="Ig-like"
FT   MOD_RES         20
FT                   /note="Pyrrolidone carboxylic acid"
FT                   /evidence="ECO:0000250|UniProtKB:P01724"
FT   NON_TER         117
SQ   SEQUENCE   117 AA;  12222 MW;  43FDF197419B42A6 CRC64;
     MAWTSLILSL LALCSGASSQ AVVTQESALT TSPGGTVILT CRSSTGAVTT SNYANWVQEK
     PDHLFTGLIG GTSNRAPGVP VRFSGSLIGD KAALTITGAQ TEDDAMYFCA LWYSTHF