ID   LV2B_MOUSE              Reviewed;         129 AA.
AC   P01729;
DT   21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT   21-JUL-1986, sequence version 1.
DT   25-MAY-2022, entry version 114.
DE   RecName: Full=Ig lambda-2 chain V region MOPC 315;
DE   Flags: Precursor;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=6287422; DOI=10.1093/nar/10.13.3831;
RA   Wu G.E., Govindji N., Hozumi N., Murialdo H.;
RT   "Nucleotide sequence of a chromosomal rearranged lambda 2 immunoglobulin
RT   gene of mouse.";
RL   Nucleic Acids Res. 10:3831-3843(1982).
RN   [2]
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=6283385; DOI=10.1038/298380a0;
RA   Bothwell A.L.M., Paskind M., Reth M., Imanishi-Kari T., Rajewsky K.,
RA   Baltimore D.;
RT   "Somatic variants of murine immunoglobulin lambda light chains.";
RL   Nature 298:380-382(1982).
RN   [3]
RP   PROTEIN SEQUENCE OF 1-22 (PRECURSOR PROTEIN).
RX   PubMed=428562;
RA   Schechter I., Wolf O., Zemell R., Burstein Y.;
RT   "Structure and function of immunoglobulin genes and precursors.";
RL   Fed. Proc. 38:1839-1845(1979).
RN   [4]
RP   PROTEIN SEQUENCE OF 20-129.
RX   PubMed=4760498;
RA   Dugan E.S., Bradshaw R.A., Simms E.S., Eisen H.N.;
RT   "Amino acid sequence of the light chain of a mouse myeloma protein (MOPC-
RT   315).";
RL   Biochemistry 12:5400-5416(1973).
RN   [5]
RP   DETERMINATION OF AMIDATION STATES OF 58; 59; 62; 100; 102 AND 115.
RX   PubMed=418802; DOI=10.1021/bi00600a032;
RA   Gavish M., Zakut R., Wilchek M., Givol D.;
RT   "Preparation of a semisynthetic antibody.";
RL   Biochemistry 17:1345-1351(1978).
CC   -!- MISCELLANEOUS: This chain is from a myeloma protein with anti-DNP
CC       activity.
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DR   PIR; A27633; A27633.
DR   PIR; A93431; L2MS35.
DR   PIR; PL0192; PL0192.
DR   AlphaFoldDB; P01729; -.
DR   SMR; P01729; -.
DR   MaxQB; P01729; -.
DR   PRIDE; P01729; -.
DR   PhylomeDB; P01729; -.
DR   Proteomes; UP000000589; Unplaced.
DR   RNAct; P01729; protein.
DR   GO; GO:0005615; C:extracellular space; IBA:GO_Central.
DR   GO; GO:0019814; C:immunoglobulin complex; IEA:UniProtKB-KW.
DR   GO; GO:0002250; P:adaptive immune response; IEA:UniProtKB-KW.
DR   GO; GO:0006955; P:immune response; IBA:GO_Central.
DR   Gene3D; 2.60.40.10; -; 1.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR003599; Ig_sub.
DR   InterPro; IPR013106; Ig_V-set.
DR   Pfam; PF07686; V-set; 1.
DR   SMART; SM00409; IG; 1.
DR   SMART; SM00406; IGv; 1.
DR   SUPFAM; SSF48726; SSF48726; 1.
DR   PROSITE; PS50835; IG_LIKE; 1.
PE   1: Evidence at protein level;
KW   Adaptive immunity; Direct protein sequencing; Immunity; Immunoglobulin;
KW   Pyrrolidone carboxylic acid; Reference proteome; Signal.
FT   SIGNAL          1..19
FT                   /evidence="ECO:0000269|PubMed:4760498,
FT                   ECO:0000269|PubMed:6287422"
FT   CHAIN           20..129
FT                   /note="Ig lambda-2 chain V region MOPC 315"
FT                   /id="PRO_0000015206"
FT   DOMAIN          20..125
FT                   /note="Ig-like"
FT   MOD_RES         20
FT                   /note="Pyrrolidone carboxylic acid"
FT                   /evidence="ECO:0000250|UniProtKB:P01724"
FT   NON_TER         129
SQ   SEQUENCE   129 AA;  13418 MW;  0AA6E8125723552C CRC64;
     MAWTSLILSL LALCSGASSQ AVVTQESALT TSPGGTVILT CRSSTGAVTT SNYANWIQEK
     PDHLFTGLIG GTSNRAPGVP VRFSGSLIGD KAALTITGAQ TEDDAMYFCA LWFRNHFVFG
     GGTKVTVLG