LVSF_DICDI
ID LVSF_DICDI Reviewed; 1154 AA.
AC Q54PP7; Q8IHL1;
DT 08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT 24-MAY-2005, sequence version 1.
DT 25-MAY-2022, entry version 108.
DE RecName: Full=BEACH domain-containing protein lvsF;
GN Name=lvsF; ORFNames=DDB_G0284333;
OS Dictyostelium discoideum (Slime mold).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=44689;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=NC4A2;
RX PubMed=12210762; DOI=10.1002/jcb.10254;
RA Wang N., Wu W.I., De Lozanne A.;
RT "BEACH family of proteins: phylogenetic and functional analysis of six
RT Dictyostelium BEACH proteins.";
RL J. Cell. Biochem. 86:561-570(2002).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4;
RX PubMed=15875012; DOI=10.1038/nature03481;
RA Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT "The genome of the social amoeba Dictyostelium discoideum.";
RL Nature 435:43-57(2005).
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DR EMBL; AY159037; AAN38984.1; -; Genomic_DNA.
DR EMBL; AAFI02000064; EAL65214.1; -; Genomic_DNA.
DR RefSeq; XP_638607.1; XM_633515.1.
DR AlphaFoldDB; Q54PP7; -.
DR SMR; Q54PP7; -.
DR STRING; 44689.DDB0220121; -.
DR PaxDb; Q54PP7; -.
DR PRIDE; Q54PP7; -.
DR EnsemblProtists; EAL65214; EAL65214; DDB_G0284333.
DR GeneID; 8624578; -.
DR KEGG; ddi:DDB_G0284333; -.
DR dictyBase; DDB_G0284333; lvsF.
DR eggNOG; KOG1786; Eukaryota.
DR HOGENOM; CLU_000218_5_2_1; -.
DR InParanoid; Q54PP7; -.
DR OMA; QVYKRRY; -.
DR PhylomeDB; Q54PP7; -.
DR PRO; PR:Q54PP7; -.
DR Proteomes; UP000002195; Chromosome 4.
DR CDD; cd06071; Beach; 1.
DR CDD; cd01201; PH_BEACH; 1.
DR Gene3D; 1.10.1540.10; -; 1.
DR Gene3D; 2.130.10.10; -; 2.
DR Gene3D; 2.30.29.30; -; 1.
DR InterPro; IPR000409; BEACH_dom.
DR InterPro; IPR036372; BEACH_dom_sf.
DR InterPro; IPR023362; PH-BEACH_dom.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR001680; WD40_repeat.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR Pfam; PF02138; Beach; 1.
DR Pfam; PF14844; PH_BEACH; 1.
DR Pfam; PF00400; WD40; 1.
DR SMART; SM01026; Beach; 1.
DR SMART; SM00320; WD40; 7.
DR SUPFAM; SSF50978; SSF50978; 1.
DR SUPFAM; SSF81837; SSF81837; 1.
DR PROSITE; PS50197; BEACH; 1.
DR PROSITE; PS51783; PH_BEACH; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 2.
DR PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE 4: Predicted;
KW Reference proteome; Repeat; WD repeat.
FT CHAIN 1..1154
FT /note="BEACH domain-containing protein lvsF"
FT /id="PRO_0000327712"
FT DOMAIN 289..384
FT /note="BEACH-type PH"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01119"
FT DOMAIN 389..697
FT /note="BEACH"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00026"
FT REPEAT 858..897
FT /note="WD 1"
FT REPEAT 900..939
FT /note="WD 2"
FT REPEAT 942..980
FT /note="WD 3"
FT REPEAT 992..1031
FT /note="WD 4"
FT REPEAT 1034..1074
FT /note="WD 5"
FT REPEAT 1076..1110
FT /note="WD 6"
FT REPEAT 1119..1154
FT /note="WD 7"
FT REGION 92..123
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 139..167
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 554..575
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 739..762
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 779..825
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 92..120
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 145..162
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 161
FT /note="S -> F (in Ref. 1; AAN38984)"
FT /evidence="ECO:0000305"
FT CONFLICT 229
FT /note="Q -> QVSKN (in Ref. 1; AAN38984)"
FT /evidence="ECO:0000305"
FT CONFLICT 729..835
FT /note="Missing (in Ref. 1; AAN38984)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 1154 AA; 131488 MW; 476A8870505EC77B CRC64;
MFSKNINKVR FNLTLMDEGE YYFDDYSAIF YPPSNTEEES WQKRIAGRIL VCSSSMFFEP
DDSKLPIMKF PYKDMSSIGA WLNSLSSAPP AHLPTPQPIP QSILSPSKPT PTPTPPIVVE
QPSPTRSAFS RLLSFSSLTS KVTTPTPPTP TPTPPTPQPT SIAPTPTIAT NPYTSFSVSP
NPPSPLLSQL FEQAKPSFLA SKGDIFYVKS SQVIEMKENS RNHPYIFKQY NNIDFKFSFN
YVKQNIVLDV MKVFHNYSGK EKIQRDELIK QMVEDRENKI FFDITQLVDM NERNILELKC
SKISPLVENP GRLLITNARL YFQPMNNIEE NRLKNYSLQS IIRVLQRRHS LREIGLELFF
DDGSSLFLKF NNTITRNQVY DLLVKHLCTN IMHINEQANY LLKWQNGIIS NYDYLLYLNN
LAGRTFNDLT QYPVFPWIIA DYQSTTLDLN RNETFRDLSK PIGALNPTRL ATFQDRYHQI
PDDQPKFLYG THYSTPAYVL YFLVRQVPEY MLRLQNGRFD SPNRMFYSIE ETWNSVLNST
TDVKELIPEF YKPSFESSSS SRNGGGGDDD DNFENGIFLT NSENLPLGIR QDNNVINDII
LPPWASSPKD FISKLHQALE SEYVSQNLHH WIDLIFGYKQ KGEEAVRANN LFYHLTYEGS
IDIESITNPF EREGMEAQIN EFGQTPRQIF KTPHPQRLPQ QLRNQNLKIE LSDLEQNINF
IFDELNNCNI NELNNDNDNN LNNNNNNNNN NNSNSNSNLN NNYIDSNINN NINNIENINS
LNNENNENSN DKKNNSNSNS SDNIKNSNGF ENNDNNFNNE NENLNDENEN LTFLGEERNN
SNNWGSLNFL KFNQNIKLHK DKISALYLSN NSETIYSVSL DSCLKIYSLK EKRQIRSLNL
CNLALSSFQL SKDEKYIIIG SWDNNIYVYS VGNGSISYSI PGHSDAVSCL KLHNNNILVS
GSWDSSVKVW RTHRQSNGAI SIEKTPIADF VDSDTEIRSI DISSNGTIFC AGSSDGYLYF
YDLLTLQLIR RISCFFDELV CIKFTPDGSR IITACIDGSV KLIGIEGSEI FSFKVKGEIH
CLDSDGSSLI IGTDRGLCLW SLTTGTEIKD SISPFLSQSS NESIHSLNVS INQSSNKPIL
LTGTEAGSIS IWQQ
