ID   LVSG_DICDI              Reviewed;        2179 AA.
AC   Q55FJ0;
DT   10-FEB-2009, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   25-MAY-2022, entry version 109.
DE   RecName: Full=Probable inactive serine/threonine-protein kinase lvsG;
DE   AltName: Full=Large volume sphere mutant lvsA-like protein G;
GN   Name=lvsG; ORFNames=DDB_G0268088;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
CC   -!- DOMAIN: The protein kinase domain is predicted to be catalytically
CC       inactive.
CC   -!- SIMILARITY: Belongs to the protein kinase superfamily. Ser/Thr protein
CC       kinase family. {ECO:0000305}.
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DR   EMBL; AAFI02000003; EAL73497.1; -; Genomic_DNA.
DR   RefSeq; XP_647543.1; XM_642451.1.
DR   AlphaFoldDB; Q55FJ0; -.
DR   SMR; Q55FJ0; -.
DR   STRING; 44689.DDB0231499; -.
DR   PaxDb; Q55FJ0; -.
DR   EnsemblProtists; EAL73497; EAL73497; DDB_G0268088.
DR   GeneID; 8616350; -.
DR   KEGG; ddi:DDB_G0268088; -.
DR   dictyBase; DDB_G0268088; lvsG.
DR   eggNOG; KOG1786; Eukaryota.
DR   HOGENOM; CLU_231449_0_0_1; -.
DR   InParanoid; Q55FJ0; -.
DR   OMA; YIHHILP; -.
DR   PRO; PR:Q55FJ0; -.
DR   Proteomes; UP000002195; Chromosome 1.
DR   CDD; cd06071; Beach; 1.
DR   Gene3D; 1.10.1540.10; -; 1.
DR   Gene3D; 2.130.10.10; -; 2.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR000409; BEACH_dom.
DR   InterPro; IPR036372; BEACH_dom_sf.
DR   InterPro; IPR011009; Kinase-like_dom_sf.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR001680; WD40_repeat.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   Pfam; PF02138; Beach; 1.
DR   Pfam; PF00400; WD40; 1.
DR   SMART; SM01026; Beach; 1.
DR   SMART; SM00320; WD40; 6.
DR   SUPFAM; SSF48371; SSF48371; 1.
DR   SUPFAM; SSF50978; SSF50978; 1.
DR   SUPFAM; SSF56112; SSF56112; 2.
DR   SUPFAM; SSF81837; SSF81837; 1.
DR   PROSITE; PS50197; BEACH; 1.
DR   PROSITE; PS50082; WD_REPEATS_2; 1.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE   3: Inferred from homology;
KW   Coiled coil; Reference proteome; Repeat; WD repeat.
FT   CHAIN           1..2179
FT                   /note="Probable inactive serine/threonine-protein kinase
FT                   lvsG"
FT                   /id="PRO_0000362022"
FT   REPEAT          216..256
FT                   /note="WD 1"
FT   DOMAIN          463..801
FT                   /note="BEACH"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00026"
FT   DOMAIN          1064..1400
FT                   /note="Protein kinase"
FT   REPEAT          1864..1903
FT                   /note="WD 2"
FT   REPEAT          1906..1942
FT                   /note="WD 3"
FT   REPEAT          1945..1983
FT                   /note="WD 4"
FT   REPEAT          2007..2048
FT                   /note="WD 5"
FT   REPEAT          2052..2089
FT                   /note="WD 6"
FT   REPEAT          2149..2179
FT                   /note="WD 7"
FT   REGION          100..167
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          281..300
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          523..556
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          589..621
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          778..801
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          844..959
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1033..1055
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1079..1153
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1339..1362
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1785..1807
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          1021..1049
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        142..167
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        533..556
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        599..616
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        781..801
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        854..947
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   2179 AA;  245159 MW;  969F8D73DE24F538 CRC64;
     MGQTVSKEEI KEEIEKQLNI CFLSLDQEDI HSKNSISFNL STVSAHKGSI DFIFNKTSNN
     NSSLIGSNGF VNISNNNIID DLIKDKSTSI LLQYANKHND HDLNKNKNNN NNSEENNNNS
     GEGDEDNTGE KAPPPAPSSP LSPSSSSSTS TTTTPLSTSI SLNDLNSMPR KRTTIKYKQG
     SFEASSYDGD EISIQVVKKN WINNSNDNNS QQRPRLYERS LKTSQQQQQQ QQQQFKFQPN
     ETLSLWEYFD EINSPPMLYN IDQNNLNFTN NYIVQEKLNS LDNKDDDDNN NNNNNSNSQS
     FTFNKEFIKS VLQSFSTYIS SLPNSIHFTD TNIPPSIDYT SPNVLKLHPN LLPIIEIIYN
     DIDNNDNDND DDDDKNNNNL NDKIFIIYKK YNYTLDGLLR YSLQYLQRNQ KITTFMIYQL
     IQLFSFLHQR EIVHGDLQPS NIHLNNQMWL GLEGFSFPST PLYHQPLENQ FESSMNKWIN
     GELSNFNYLM ILNHLAHRHI GDPMNHPVLP WVIDFTTSPI NIDNDNDSRD DVDNSSSSNN
     NNNNNNEDQS GKTVGWRDLT KTKYRLNKGD EQLDFQFFNT GNSTTLGDDS MGGGIGSIGS
     TGGITNSSNN GGGGGSGNSG KAHHISDILS ELTYYSYLAR RTSVPLLRRF VRTNYEPNEY
     PATMERLYRW TPDECIPEFF TDSTIFKSIH SDMPDLQLPD WVPNQSTQEF IKIHMNALES
     DHVSKQLHSW IDLTFGYLLS GEEAIKAKNL ALMDTTIPRN NGIVQLFNHP HPKKKYLKSL
     KYQRQQQTQQ HQQQTQQQPQ FDTEFTIKFN ESSFRYENQN INHNSTFLPN TTINSILNNL
     SNVNNHHHHH SHNSNIPNTV SSRSDSFGSN SSSSAPGNSN SNILLSPSMS SSMGSLNSAT
     SPSSQSQSSH QQTSSTPTSQ TQRSFSIINN NNSSSSSNSG VNNKPRTSSG KKEGENKPSL
     AKFLPSLFTQ AIKIEKEDNS IVSSSPTNTP VQIDLLSSVN SNYIGYGSSI GNSSMQHQLY
     LQQQLQQQQQ QQAQQQQSQQ QSQQQQANSP NSKQLHLIHS KSEESMIKKY SNGLFSSMGI
     SKSTTNAPTT NNTTTNSNMG DSIGNNITSP PSPTSLKDSS SIQQQQQQQQ QQQQNSESTR
     PITPPNVSNS TTDLSSIYTN QEHIIEPLPA ELELELYEYE LLNKDVTGIN ANIIYSSSPT
     NVSTTTNTTT STTQPYIIYN NNTTQNNVAS YHSQQKKPNV FIESLLNCEL NNEFGHNFEN
     LLPIYRPLEF NDNNSGSSEL SIDNEKNKGL IKIFSNNKEQ SNLEILKSND MFALGCIIAE
     LYQGYPLFTS KGLENHFLNH SNSSNNNNNN NNNNNNNNKN GSFMITSNLP NNVKEIVDKL
     IQPNPMERSE VNELLSSSLF PNYFKQMYHF LVHYHSLNTP EERLTFTLAN IGIVTSLPNE
     SIDLILPFIL ELFYDSKTMV SALIDLLDPL SQRLGIHLST SYLLPCLIAL YQRHDDHLLQ
     CHLIQIPMID MIVSRFGRDV YIHHILPFLL DSVKTNPKDN PNHEMLTTAL IKISKVLGIP
     LTIRHMMYPL LVALTKPRLQ HLNEPLVAIA SSLGENVIVK FYFPSIFILI QKHSSKASRS
     ESIPCTLLSL LQELILLVKP GLVLRSLLKE STQLASLLLN PSNTSLLLPL AETLLRISGR
     IGVNHTKNYI LKYVQQFFSN YSDLYDYSGD NSYAKIGGDS ETTKQLRSIY SPEMTYYLYY
     KLARIIGFEV MRAEISDNSL IEHIMRIYIK ENNIKTTNST ITTTTTTTTT TTTTTTTNNN
     NENPNSLNFI PPYVSDDGLY DIIEETLDQK ISSTYLLDDY QDYDDLICDK TFTLQGNIVA
     QYKEHNASIK SLAVSPSEER FISGSKDNLV KIWSLDSTKS LTTYNQHMHT AHTVHFVSSL
     VASCDITSIQ VWDPESKIKV NVFYEPTGSF SCFEPISSKY LIASTCESTL SFYDLSMGSL
     THEWSLAYQT GQAIRCIATS NDHLIGSNSN QFSSSSFIAS ATPTWVATGS SSGMITLLDT
     RTGTILEQWK SHHDSPVNKL IAQGSRYLIS CGDKSVIQWD LHQSPPIISK MWKGFKDNIT
     NASLYQNDLI VSSGHKLSSM TLLDDPYQLT SGGGNQNTFR VDGLKLNTPK QSNILSLSFF
     PLHHVLLAGT DDGFIKICQ