ID   LY65C_CANLF             Reviewed;         128 AA.
AC   Q9XSV5;
DT   18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1999, sequence version 1.
DT   03-AUG-2022, entry version 81.
DE   RecName: Full=Lymphocyte antigen 6 complex locus protein G5c;
DE   AltName: Full=Canine epididymal gene product 8;
DE            Short=CE8;
DE   AltName: Full=Epididymal secretory protein 8;
DE   Flags: Precursor;
GN   Name=LY6G5C; Synonyms=CE8;
OS   Canis lupus familiaris (Dog) (Canis familiaris).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis.
OX   NCBI_TaxID=9615;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA], AND TISSUE SPECIFICITY.
RC   STRAIN=Mongrel; TISSUE=Epididymis;
RX   PubMed=10615266; DOI=10.1530/jrf.0.1160391;
RA   Gebhardt K., Ellerbrock K., Pera I., Ivell R., Kirchhoff C.;
RT   "Differential expression of novel abundant and highly regionalized mRNAs of
RT   the canine epididymis.";
RL   J. Reprod. Fertil. 116:391-402(1999).
CC   -!- FUNCTION: May have a role in hematopoietic cell differentiation.
CC       {ECO:0000250}.
CC   -!- SUBUNIT: Forms oligomers. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC   -!- TISSUE SPECIFICITY: Abundantly expressed in the epididymis.
CC       {ECO:0000269|PubMed:10615266}.
CC   -!- PTM: N-glycosylated. {ECO:0000250}.
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DR   EMBL; AJ238952; CAB50694.1; -; mRNA.
DR   RefSeq; NP_001003166.1; NM_001003166.1.
DR   AlphaFoldDB; Q9XSV5; -.
DR   STRING; 9612.ENSCAFP00000000849; -.
DR   Ensembl; ENSCAFT00030008091; ENSCAFP00030007110; ENSCAFG00030004390.
DR   Ensembl; ENSCAFT00040019692; ENSCAFP00040017092; ENSCAFG00040010644.
DR   Ensembl; ENSCAFT00845020501; ENSCAFP00845016072; ENSCAFG00845011560.
DR   GeneID; 403793; -.
DR   KEGG; cfa:403793; -.
DR   CTD; 80741; -.
DR   VEuPathDB; HostDB:ENSCAFG00845011560; -.
DR   eggNOG; ENOG502TD7Y; Eukaryota.
DR   GeneTree; ENSGT00390000011513; -.
DR   InParanoid; Q9XSV5; -.
DR   OrthoDB; 1440854at2759; -.
DR   Proteomes; UP000002254; Chromosome 12.
DR   Bgee; ENSCAFG00000000606; Expressed in granulocyte and 37 other tissues.
DR   GO; GO:0009897; C:external side of plasma membrane; IEA:Ensembl.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0032991; C:protein-containing complex; IEA:Ensembl.
DR   GO; GO:0042802; F:identical protein binding; IEA:Ensembl.
DR   InterPro; IPR026110; LY6G5C.
DR   PANTHER; PTHR14909; PTHR14909; 1.
PE   2: Evidence at transcript level;
KW   Disulfide bond; Glycoprotein; Reference proteome; Secreted; Signal.
FT   SIGNAL          1..29
FT                   /evidence="ECO:0000255"
FT   CHAIN           30..128
FT                   /note="Lymphocyte antigen 6 complex locus protein G5c"
FT                   /id="PRO_0000323015"
FT   DOMAIN          37..128
FT                   /note="UPAR/Ly6"
FT   CARBOHYD        73
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   DISULFID        39..66
FT                   /evidence="ECO:0000250"
FT   DISULFID        42..51
FT                   /evidence="ECO:0000250"
FT   DISULFID        58..85
FT                   /evidence="ECO:0000250"
FT   DISULFID        94..111
FT                   /evidence="ECO:0000250"
FT   DISULFID        112..117
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   128 AA;  14464 MW;  21642B982D29EF2B CRC64;
     MGAEYGCLPS TSQALYVILL IVLVRMSLVF VQFPKYLRCY RCLLETKELG CLLGSDICLA
     PPGSSCMTLL IKNSSSGSDI MVSDCRHKEQ MSDCSYTRSS PVFGFWIFSR CCLREFCNNP
     QNRVFYIP