ID   LY66D_RAT               Reviewed;         134 AA.
AC   Q6MG58;
DT   18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 87.
DE   RecName: Full=Lymphocyte antigen 6 complex locus protein G6d;
DE   Flags: Precursor;
GN   Name=Ly6g6d;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Brown Norway;
RX   PubMed=15060004; DOI=10.1101/gr.1987704;
RA   Hurt P., Walter L., Sudbrak R., Klages S., Mueller I., Shiina T., Inoko H.,
RA   Lehrach H., Guenther E., Reinhardt R., Himmelbauer H.;
RT   "The genomic sequence and comparative analysis of the rat major
RT   histocompatibility complex.";
RL   Genome Res. 14:631-639(2004).
CC   -!- SUBUNIT: Homodimer. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Lipid-anchor, GPI-
CC       anchor {ECO:0000250}.
CC   -!- PTM: O-glycosylated. {ECO:0000250}.
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DR   EMBL; BX883045; CAE83988.1; -; Genomic_DNA.
DR   RefSeq; NP_001001970.1; NM_001001970.1.
DR   AlphaFoldDB; Q6MG58; -.
DR   SMR; Q6MG58; -.
DR   STRING; 10116.ENSRNOP00000001120; -.
DR   GlyGen; Q6MG58; 1 site.
DR   PaxDb; Q6MG58; -.
DR   Ensembl; ENSRNOT00000001120; ENSRNOP00000001120; ENSRNOG00000027225.
DR   GeneID; 415062; -.
DR   KEGG; rno:415062; -.
DR   UCSC; RGD:1303064; rat.
DR   CTD; 58530; -.
DR   RGD; 1303064; Ly6g6d.
DR   eggNOG; ENOG502SNF5; Eukaryota.
DR   GeneTree; ENSGT00390000015960; -.
DR   HOGENOM; CLU_1824727_0_0_1; -.
DR   InParanoid; Q6MG58; -.
DR   OMA; QHQPACV; -.
DR   OrthoDB; 1493078at2759; -.
DR   PhylomeDB; Q6MG58; -.
DR   Reactome; R-RNO-163125; Post-translational modification: synthesis of GPI-anchored proteins.
DR   PRO; PR:Q6MG58; -.
DR   Proteomes; UP000002494; Chromosome 20.
DR   Bgee; ENSRNOG00000000844; Expressed in cerebellum and 13 other tissues.
DR   ExpressionAtlas; Q6MG58; baseline and differential.
DR   GO; GO:0031225; C:anchored component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0032991; C:protein-containing complex; ISO:RGD.
DR   GO; GO:0045202; C:synapse; IEA:GOC.
DR   GO; GO:0030550; F:acetylcholine receptor inhibitor activity; ISO:RGD.
DR   GO; GO:0042802; F:identical protein binding; ISO:RGD.
DR   GO; GO:0095500; P:acetylcholine receptor signaling pathway; ISO:RGD.
DR   Gene3D; 2.10.60.10; -; 1.
DR   InterPro; IPR026524; LY6G6d/LY6G6f.
DR   InterPro; IPR045860; Snake_toxin-like_sf.
DR   PANTHER; PTHR32286; PTHR32286; 1.
DR   SUPFAM; SSF57302; SSF57302; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Disulfide bond; Glycoprotein; GPI-anchor; Lipoprotein;
KW   Membrane; Reference proteome; Signal.
FT   SIGNAL          1..19
FT                   /evidence="ECO:0000255"
FT   CHAIN           20..108
FT                   /note="Lymphocyte antigen 6 complex locus protein G6d"
FT                   /id="PRO_0000323711"
FT   PROPEP          109..134
FT                   /note="Removed in mature form"
FT                   /evidence="ECO:0000255"
FT                   /id="PRO_0000323712"
FT   DOMAIN          22..121
FT                   /note="UPAR/Ly6"
FT   LIPID           108
FT                   /note="GPI-anchor amidated asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        68
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   DISULFID        24..48
FT                   /evidence="ECO:0000250"
FT   DISULFID        27..35
FT                   /evidence="ECO:0000250"
FT   DISULFID        42..76
FT                   /evidence="ECO:0000250"
FT   DISULFID        82..101
FT                   /evidence="ECO:0000250"
FT   DISULFID        102..107
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   134 AA;  14025 MW;  6706CB9BD8908BC6 CRC64;
     MNSQLIGILF SALLGAALGQ RMRCYDCGGG PSNSCKQTVI TCGEGERCGF LDRKPQPSSE
     QAKQPSATLS HHYPACVATH HCNQVAIESV GDVTFTTQKN CCFGDLCNGA VASSSTPLCI
     LAAVTTLAWL LSGQ