ID   LYRM1_MOUSE             Reviewed;         122 AA.
AC   Q9CQB7; Q3TZE0;
DT   26-APR-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2001, sequence version 1.
DT   03-AUG-2022, entry version 111.
DE   RecName: Full=LYR motif-containing protein 1;
GN   Name=Lyrm1;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=C57BL/6J; TISSUE=Inner ear, Testis, and Tongue;
RX   PubMed=16141072; DOI=10.1126/science.1112014;
RA   Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA   Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA   Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA   Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA   Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA   Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA   Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA   Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA   Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA   Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA   Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA   Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA   Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA   Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA   Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA   Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA   Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA   Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA   Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA   Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA   Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA   Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA   Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA   Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA   Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA   van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA   Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA   Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA   Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA   Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA   Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA   Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA   Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA   Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT   "The transcriptional landscape of the mammalian genome.";
RL   Science 309:1559-1563(2005).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
RN   [3]
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC   TISSUE=Brain;
RX   PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA   Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA   Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT   "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL   Cell 143:1174-1189(2010).
CC   -!- FUNCTION: May promote cell proliferation and inhibition of apoptosis of
CC       preadipocytes. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the complex I LYR family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AK009135; BAB26096.1; -; mRNA.
DR   EMBL; AK015083; BAB29706.1; -; mRNA.
DR   EMBL; AK157931; BAE34269.1; -; mRNA.
DR   EMBL; BC011339; AAH11339.1; -; mRNA.
DR   CCDS; CCDS21790.1; -.
DR   RefSeq; NP_001272888.1; NM_001285959.1.
DR   RefSeq; NP_001272889.1; NM_001285960.1.
DR   RefSeq; NP_001272890.1; NM_001285961.2.
DR   RefSeq; NP_083886.1; NM_029610.3.
DR   RefSeq; XP_006508297.1; XM_006508234.3.
DR   RefSeq; XP_006508298.1; XM_006508235.3.
DR   RefSeq; XP_006508299.1; XM_006508236.3.
DR   RefSeq; XP_006508300.1; XM_006508237.3.
DR   RefSeq; XP_006508301.1; XM_006508238.3.
DR   RefSeq; XP_006508302.1; XM_006508239.3.
DR   RefSeq; XP_006508303.1; XM_006508240.3.
DR   RefSeq; XP_006508304.1; XM_006508241.3.
DR   RefSeq; XP_006508306.1; XM_006508243.3.
DR   RefSeq; XP_006508307.1; XM_006508244.3.
DR   RefSeq; XP_017167827.1; XM_017312338.1.
DR   RefSeq; XP_017167828.1; XM_017312339.1.
DR   AlphaFoldDB; Q9CQB7; -.
DR   SMR; Q9CQB7; -.
DR   STRING; 10090.ENSMUSP00000102127; -.
DR   iPTMnet; Q9CQB7; -.
DR   PhosphoSitePlus; Q9CQB7; -.
DR   EPD; Q9CQB7; -.
DR   MaxQB; Q9CQB7; -.
DR   PaxDb; Q9CQB7; -.
DR   PeptideAtlas; Q9CQB7; -.
DR   PRIDE; Q9CQB7; -.
DR   ProteomicsDB; 291980; -.
DR   Antibodypedia; 42976; 85 antibodies from 21 providers.
DR   DNASU; 73919; -.
DR   Ensembl; ENSMUST00000054440; ENSMUSP00000051616; ENSMUSG00000030922.
DR   Ensembl; ENSMUST00000106516; ENSMUSP00000102126; ENSMUSG00000030922.
DR   Ensembl; ENSMUST00000106517; ENSMUSP00000102127; ENSMUSG00000030922.
DR   Ensembl; ENSMUST00000106518; ENSMUSP00000102128; ENSMUSG00000030922.
DR   Ensembl; ENSMUST00000207270; ENSMUSP00000146648; ENSMUSG00000030922.
DR   Ensembl; ENSMUST00000208202; ENSMUSP00000146699; ENSMUSG00000030922.
DR   Ensembl; ENSMUST00000208424; ENSMUSP00000146841; ENSMUSG00000030922.
DR   GeneID; 73919; -.
DR   KEGG; mmu:73919; -.
DR   UCSC; uc009jma.1; mouse.
DR   CTD; 57149; -.
DR   MGI; MGI:1921169; Lyrm1.
DR   VEuPathDB; HostDB:ENSMUSG00000030922; -.
DR   eggNOG; ENOG502S0XV; Eukaryota.
DR   GeneTree; ENSGT00390000006695; -.
DR   HOGENOM; CLU_141097_0_0_1; -.
DR   InParanoid; Q9CQB7; -.
DR   OMA; KYIVQEA; -.
DR   OrthoDB; 1552235at2759; -.
DR   PhylomeDB; Q9CQB7; -.
DR   TreeFam; TF324686; -.
DR   BioGRID-ORCS; 73919; 1 hit in 72 CRISPR screens.
DR   PRO; PR:Q9CQB7; -.
DR   Proteomes; UP000000589; Chromosome 7.
DR   RNAct; Q9CQB7; protein.
DR   Bgee; ENSMUSG00000030922; Expressed in spermatocyte and 211 other tissues.
DR   Genevisible; Q9CQB7; MM.
DR   GO; GO:0030496; C:midbody; ISO:MGI.
DR   GO; GO:0005739; C:mitochondrion; HDA:MGI.
DR   GO; GO:0005654; C:nucleoplasm; ISO:MGI.
DR   CDD; cd20261; Complex1_LYR_LYRM1; 1.
DR   InterPro; IPR008011; Complex1_LYR_dom.
DR   InterPro; IPR045294; Complex1_LYR_LYRM1.
DR   InterPro; IPR040330; LYRM1.
DR   PANTHER; PTHR14273; PTHR14273; 1.
DR   Pfam; PF05347; Complex1_LYR; 1.
PE   1: Evidence at protein level;
KW   Reference proteome.
FT   CHAIN           1..122
FT                   /note="LYR motif-containing protein 1"
FT                   /id="PRO_0000174311"
SQ   SEQUENCE   122 AA;  14224 MW;  A2E020FD0EA355E9 CRC64;
     MTAATRQEVL CLYRSIFRLA RKWQAASGQM EDTIEEKQYI LKEARTLFQK NKNLTDPELI
     KQCIVECTAR IEIGLHYQIP YPRPIHLPPM GLTARRGRGL QTQEKLRKLS KPVYLKSHDE
     VS