LYRM2_MOUSE
ID LYRM2_MOUSE Reviewed; 88 AA.
AC Q8R033; A2ANY7;
DT 03-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2002, sequence version 1.
DT 03-AUG-2022, entry version 109.
DE RecName: Full=LYR motif-containing protein 2;
GN Name=Lyrm2;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Retina;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.;
RL Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Thymus;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- SIMILARITY: Belongs to the complex I LYR family. {ECO:0000305}.
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DR EMBL; AK044791; BAC32093.1; -; mRNA.
DR EMBL; AL831774; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CH466538; EDL05501.1; -; Genomic_DNA.
DR EMBL; BC028533; AAH28533.1; -; mRNA.
DR CCDS; CCDS38703.1; -.
DR RefSeq; NP_780573.1; NM_175364.4.
DR AlphaFoldDB; Q8R033; -.
DR SMR; Q8R033; -.
DR BioGRID; 224404; 2.
DR STRING; 10090.ENSMUSP00000061451; -.
DR PhosphoSitePlus; Q8R033; -.
DR EPD; Q8R033; -.
DR MaxQB; Q8R033; -.
DR PaxDb; Q8R033; -.
DR PeptideAtlas; Q8R033; -.
DR PRIDE; Q8R033; -.
DR ProteomicsDB; 295740; -.
DR Antibodypedia; 54908; 124 antibodies from 23 providers.
DR Ensembl; ENSMUST00000062802; ENSMUSP00000061451; ENSMUSG00000045854.
DR GeneID; 108755; -.
DR KEGG; mmu:108755; -.
DR UCSC; uc008sfe.2; mouse.
DR CTD; 57226; -.
DR MGI; MGI:1917573; Lyrm2.
DR VEuPathDB; HostDB:ENSMUSG00000045854; -.
DR eggNOG; ENOG502S8DG; Eukaryota.
DR GeneTree; ENSGT00390000002957; -.
DR HOGENOM; CLU_151409_1_1_1; -.
DR InParanoid; Q8R033; -.
DR OMA; MMITQAS; -.
DR OrthoDB; 1575118at2759; -.
DR PhylomeDB; Q8R033; -.
DR TreeFam; TF323797; -.
DR BioGRID-ORCS; 108755; 1 hit in 72 CRISPR screens.
DR ChiTaRS; Lyrm2; mouse.
DR PRO; PR:Q8R033; -.
DR Proteomes; UP000000589; Chromosome 4.
DR RNAct; Q8R033; protein.
DR Bgee; ENSMUSG00000045854; Expressed in saccule of membranous labyrinth and 254 other tissues.
DR Genevisible; Q8R033; MM.
DR GO; GO:0005739; C:mitochondrion; HDA:MGI.
DR CDD; cd20262; Complex1_LYR_LYRM2; 1.
DR InterPro; IPR008011; Complex1_LYR_dom.
DR InterPro; IPR045293; Complex1_LYR_LYRM2.
DR Pfam; PF05347; Complex1_LYR; 1.
PE 3: Inferred from homology;
KW Reference proteome.
FT CHAIN 1..88
FT /note="LYR motif-containing protein 2"
FT /id="PRO_0000251176"
SQ SEQUENCE 88 AA; 10380 MW; 77CE736B6CEBB5AB CRC64;
MAASRLPPAA LTLKQFMRRQ QVLLLYRKIL RAIRQVPSDS DRKYLQDWAR EEFKRNKSAT
EEDTIRMMIT QGNMQLKELE RTLALANS