ID   LYRM4_DICDI             Reviewed;          81 AA.
AC   Q54FN9;
DT   08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   25-MAY-2022, entry version 74.
DE   RecName: Full=LYR motif-containing protein 4;
GN   Name=lyrm4; Synonyms=isd11; ORFNames=DDB_G0290725;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
CC   -!- FUNCTION: Required for nuclear and mitochondrial iron-sulfur protein
CC       biosynthesis. {ECO:0000250}.
CC   -!- PATHWAY: Cofactor biosynthesis; iron-sulfur cluster biosynthesis.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250}. Nucleus
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the complex I LYR family. {ECO:0000305}.
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DR   EMBL; AAFI02000169; EAL62068.1; -; Genomic_DNA.
DR   RefSeq; XP_635573.1; XM_630481.1.
DR   AlphaFoldDB; Q54FN9; -.
DR   SMR; Q54FN9; -.
DR   STRING; 44689.DDB0232412; -.
DR   PaxDb; Q54FN9; -.
DR   EnsemblProtists; EAL62068; EAL62068; DDB_G0290725.
DR   GeneID; 8627797; -.
DR   KEGG; ddi:DDB_G0290725; -.
DR   dictyBase; DDB_G0290725; lyrm4.
DR   eggNOG; KOG3801; Eukaryota.
DR   HOGENOM; CLU_120076_3_0_1; -.
DR   InParanoid; Q54FN9; -.
DR   OMA; AYNYRMY; -.
DR   PhylomeDB; Q54FN9; -.
DR   Reactome; R-DDI-1362409; Mitochondrial iron-sulfur cluster biogenesis.
DR   UniPathway; UPA00266; -.
DR   PRO; PR:Q54FN9; -.
DR   Proteomes; UP000002195; Chromosome 5.
DR   GO; GO:1990221; C:L-cysteine desulfurase complex; IBA:GO_Central.
DR   GO; GO:0005739; C:mitochondrion; IBA:GO_Central.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0016226; P:iron-sulfur cluster assembly; IBA:GO_Central.
DR   CDD; cd20264; Complex1_LYR_LYRM4; 1.
DR   InterPro; IPR008011; Complex1_LYR_dom.
DR   InterPro; IPR045297; Complex1_LYR_LYRM4.
DR   Pfam; PF05347; Complex1_LYR; 1.
PE   3: Inferred from homology;
KW   Mitochondrion; Nucleus; Reference proteome.
FT   CHAIN           1..81
FT                   /note="LYR motif-containing protein 4"
FT                   /id="PRO_0000328016"
SQ   SEQUENCE   81 AA;  9679 MW;  0F7352ACA021990E CRC64;
     MSQKSVVLHL YRSLVRESKK FSSYNFREYS LRRVSVGFRE NKNKDQNETK ELIQDALKNL
     EMVKRQAFIN SMYSTNKLVV E