LYRM7_DANRE
ID LYRM7_DANRE Reviewed; 104 AA.
AC A5PLG0;
DT 14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT 10-JUL-2007, sequence version 1.
DT 03-AUG-2022, entry version 53.
DE RecName: Full=Complex III assembly factor LYRM7;
DE AltName: Full=LYR motif-containing protein 7;
GN Name=LYRM7; Synonyms=MZM1L; ORFNames=zgc:165597;
OS Danio rerio (Zebrafish) (Brachydanio rerio).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Danionidae; Danioninae; Danio.
OX NCBI_TaxID=7955;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Eye;
RG NIH - Zebrafish Gene Collection (ZGC) project;
RL Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Assembly factor required for Rieske Fe-S protein UQCRFS1
CC incorporation into the cytochrome b-c1 (CIII) complex. Functions as a
CC chaperone, binding to this subunit within the mitochondrial matrix and
CC stabilizing it prior to its translocation and insertion into the late
CC CIII dimeric intermediate within the mitochondrial inner membrane (By
CC similarity). {ECO:0000250}.
CC -!- SUBUNIT: Interacts with UQCRFS1. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion matrix {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the complex I LYR family. {ECO:0000305}.
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DR EMBL; BC142889; AAI42890.1; -; mRNA.
DR RefSeq; NP_001092229.1; NM_001098759.1.
DR AlphaFoldDB; A5PLG0; -.
DR SMR; A5PLG0; -.
DR STRING; 7955.ENSDARP00000099103; -.
DR PaxDb; A5PLG0; -.
DR PeptideAtlas; A5PLG0; -.
DR GeneID; 100002948; -.
DR KEGG; dre:100002948; -.
DR CTD; 90624; -.
DR ZFIN; ZDB-GENE-070615-32; lyrm7.
DR eggNOG; ENOG502S5FU; Eukaryota.
DR InParanoid; A5PLG0; -.
DR OrthoDB; 1585902at2759; -.
DR PhylomeDB; A5PLG0; -.
DR PRO; PR:A5PLG0; -.
DR Proteomes; UP000000437; Genome assembly.
DR Proteomes; UP000814640; Unplaced.
DR GO; GO:0005759; C:mitochondrial matrix; IBA:GO_Central.
DR GO; GO:0044183; F:protein folding chaperone; IBA:GO_Central.
DR GO; GO:0045333; P:cellular respiration; IBA:GO_Central.
DR GO; GO:0034551; P:mitochondrial respiratory chain complex III assembly; IBA:GO_Central.
DR CDD; cd20267; Complex1_LYR_LYRM7; 1.
DR InterPro; IPR008011; Complex1_LYR_dom.
DR InterPro; IPR045298; Complex1_LYR_LYRM7.
DR Pfam; PF05347; Complex1_LYR; 1.
PE 3: Inferred from homology;
KW Chaperone; Mitochondrion; Reference proteome.
FT CHAIN 1..104
FT /note="Complex III assembly factor LYRM7"
FT /id="PRO_0000370341"
SQ SEQUENCE 104 AA; 12206 MW; F36C531AD1C8441A CRC64;
MGTRLKVLRV FKDLHRTRRD VFRDDNRALT AARVKINEEF KKNKNETSDD NIKEMLKMAR
AVETILRESV IQAEHVDENK IVLRPRKSLL LENVPYCDAP SKKT