LYRM7_DICDI
ID LYRM7_DICDI Reviewed; 140 AA.
AC Q9GPS1; Q55CY4;
DT 08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2001, sequence version 1.
DT 03-AUG-2022, entry version 68.
DE RecName: Full=Complex III assembly factor LYRM7;
DE AltName: Full=LYR motif-containing protein 7;
GN Name=lyrm7; Synonyms=MZM1L;
OS Dictyostelium discoideum (Slime mold).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=44689;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=AX4;
RX PubMed=11222756; DOI=10.1093/nar/29.5.1068;
RA Rivero F., Dislich H., Gloeckner G., Noegel A.A.;
RT "The Dictyostelium discoideum family of Rho-related proteins.";
RL Nucleic Acids Res. 29:1068-1079(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4;
RX PubMed=15875012; DOI=10.1038/nature03481;
RA Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT "The genome of the social amoeba Dictyostelium discoideum.";
RL Nature 435:43-57(2005).
CC -!- FUNCTION: Assembly factor required for Rieske Fe-S protein UQCRFS1
CC incorporation into the cytochrome b-c1 (CIII) complex. Functions as a
CC chaperone, binding to this subunit within the mitochondrial matrix and
CC stabilizing it prior to its translocation and insertion into the late
CC CIII dimeric intermediate within the mitochondrial inner membrane (By
CC similarity). {ECO:0000250}.
CC -!- SUBUNIT: Interacts with UQCRFS1. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion matrix {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the complex I LYR family. {ECO:0000305}.
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DR EMBL; AF310893; AAG45129.1; -; Genomic_DNA.
DR EMBL; AAFI02000005; EAL71959.1; -; Genomic_DNA.
DR RefSeq; XP_646347.1; XM_641255.1.
DR AlphaFoldDB; Q9GPS1; -.
DR SMR; Q9GPS1; -.
DR STRING; 44689.DDB0191315; -.
DR PaxDb; Q9GPS1; -.
DR EnsemblProtists; EAL71959; EAL71959; DDB_G0269218.
DR GeneID; 8617302; -.
DR KEGG; ddi:DDB_G0269218; -.
DR dictyBase; DDB_G0269218; lyrm7.
DR HOGENOM; CLU_1838905_0_0_1; -.
DR InParanoid; Q9GPS1; -.
DR OMA; EMIDHAN; -.
DR PhylomeDB; Q9GPS1; -.
DR PRO; PR:Q9GPS1; -.
DR Proteomes; UP000002195; Chromosome 1.
DR GO; GO:0005759; C:mitochondrial matrix; IBA:GO_Central.
DR GO; GO:0044183; F:protein folding chaperone; IBA:GO_Central.
DR GO; GO:0045333; P:cellular respiration; IBA:GO_Central.
DR GO; GO:0034551; P:mitochondrial respiratory chain complex III assembly; IBA:GO_Central.
DR CDD; cd20267; Complex1_LYR_LYRM7; 1.
DR InterPro; IPR008011; Complex1_LYR_dom.
DR InterPro; IPR045298; Complex1_LYR_LYRM7.
DR Pfam; PF05347; Complex1_LYR; 1.
PE 3: Inferred from homology;
KW Chaperone; Mitochondrion; Reference proteome.
FT CHAIN 1..140
FT /note="Complex III assembly factor LYRM7"
FT /id="PRO_0000327857"
FT REGION 93..140
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 140 AA; 16104 MW; 8CEC5C49BB3B0643 CRC64;
MNRAKVLSSY LGLLRTEKKV FQNDKRALEH VINLTRVQFR DNKNETDNTK INEMIDHANA
VSHFLVKDLI QGVRKDEKTI QLKFDENTKS YQQYEFVNDQ PPQRKKRGKI QIDDEQPTTC
CGGGCGKPMP SNNSEKSTCS