LYRM7_PONAB
ID LYRM7_PONAB Reviewed; 104 AA.
AC Q5REC3;
DT 03-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT 21-DEC-2004, sequence version 1.
DT 03-AUG-2022, entry version 46.
DE RecName: Full=Complex III assembly factor LYRM7;
DE AltName: Full=LYR motif-containing protein 7;
GN Name=LYRM7; Synonyms=MZM1L;
OS Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pongo.
OX NCBI_TaxID=9601;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Brain cortex;
RG The German cDNA consortium;
RL Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Assembly factor required for Rieske Fe-S protein UQCRFS1
CC incorporation into the cytochrome b-c1 (CIII) complex. Functions as a
CC chaperone, binding to this subunit within the mitochondrial matrix and
CC stabilizing it prior to its translocation and insertion into the late
CC CIII dimeric intermediate within the mitochondrial inner membrane (By
CC similarity). {ECO:0000250}.
CC -!- SUBUNIT: Interacts with UQCRFS1. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion matrix {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the complex I LYR family. {ECO:0000305}.
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DR EMBL; CR857609; CAH89884.1; -; mRNA.
DR RefSeq; NP_001124878.1; NM_001131406.1.
DR AlphaFoldDB; Q5REC3; -.
DR SMR; Q5REC3; -.
DR STRING; 9601.ENSPPYP00000017610; -.
DR Ensembl; ENSPPYT00000046530; ENSPPYP00000044597; ENSPPYG00000030710.
DR GeneID; 100171743; -.
DR KEGG; pon:100171743; -.
DR CTD; 90624; -.
DR eggNOG; ENOG502S5FU; Eukaryota.
DR GeneTree; ENSGT00390000017923; -.
DR InParanoid; Q5REC3; -.
DR OrthoDB; 1585902at2759; -.
DR Proteomes; UP000001595; Chromosome 5.
DR GO; GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
DR GO; GO:0031966; C:mitochondrial membrane; IEA:Ensembl.
DR GO; GO:0045333; P:cellular respiration; IEA:Ensembl.
DR GO; GO:0034551; P:mitochondrial respiratory chain complex III assembly; IEA:Ensembl.
DR CDD; cd20267; Complex1_LYR_LYRM7; 1.
DR InterPro; IPR008011; Complex1_LYR_dom.
DR InterPro; IPR045298; Complex1_LYR_LYRM7.
DR Pfam; PF05347; Complex1_LYR; 1.
PE 3: Inferred from homology;
KW Chaperone; Mitochondrion; Phosphoprotein; Reference proteome.
FT CHAIN 1..104
FT /note="Complex III assembly factor LYRM7"
FT /id="PRO_0000251181"
FT MOD_RES 60
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q5U5X0"
SQ SEQUENCE 104 AA; 11951 MW; 21DAEA7671FE8118 CRC64;
MGQAVKVLQL FKTLHRTRQQ VFKNDARALE AARIKINEEF KKNKSETSPK KIEELMKIGS
DVELLLRTSV IQGIHTDHNT LKLVPRKDLL VENVPYCDAP TQKQ