LYRM7_RAT
ID LYRM7_RAT Reviewed; 104 AA.
AC B4F7A1;
DT 14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT 23-SEP-2008, sequence version 1.
DT 03-AUG-2022, entry version 58.
DE RecName: Full=Complex III assembly factor LYRM7;
DE AltName: Full=LYR motif-containing protein 7;
GN Name=Lyrm7; Synonyms=MZM1L;
OS Rattus norvegicus (Rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Rattus.
OX NCBI_TaxID=10116;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Kidney;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- FUNCTION: Assembly factor required for Rieske Fe-S protein UQCRFS1
CC incorporation into the cytochrome b-c1 (CIII) complex. Functions as a
CC chaperone, binding to this subunit within the mitochondrial matrix and
CC stabilizing it prior to its translocation and insertion into the late
CC CIII dimeric intermediate within the mitochondrial inner membrane (By
CC similarity). {ECO:0000250}.
CC -!- SUBUNIT: Interacts with UQCRFS1. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion matrix {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the complex I LYR family. {ECO:0000305}.
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DR EMBL; BC168191; AAI68191.1; -; mRNA.
DR RefSeq; NP_001128201.1; NM_001134729.1.
DR AlphaFoldDB; B4F7A1; -.
DR SMR; B4F7A1; -.
DR STRING; 10116.ENSRNOP00000065804; -.
DR iPTMnet; B4F7A1; -.
DR PhosphoSitePlus; B4F7A1; -.
DR PaxDb; B4F7A1; -.
DR PeptideAtlas; B4F7A1; -.
DR PRIDE; B4F7A1; -.
DR GeneID; 686506; -.
DR KEGG; rno:686506; -.
DR UCSC; RGD:1596391; rat.
DR CTD; 90624; -.
DR RGD; 1596391; Lyrm7.
DR VEuPathDB; HostDB:ENSRNOG00000045961; -.
DR eggNOG; ENOG502S5FU; Eukaryota.
DR HOGENOM; CLU_147114_1_1_1; -.
DR InParanoid; B4F7A1; -.
DR OMA; QNRNETN; -.
DR OrthoDB; 1585902at2759; -.
DR PhylomeDB; B4F7A1; -.
DR PRO; PR:B4F7A1; -.
DR Proteomes; UP000002494; Chromosome 10.
DR Bgee; ENSRNOG00000045961; Expressed in testis and 19 other tissues.
DR Genevisible; B4F7A1; RN.
DR GO; GO:0005759; C:mitochondrial matrix; ISO:RGD.
DR GO; GO:0031966; C:mitochondrial membrane; ISO:RGD.
DR GO; GO:0044183; F:protein folding chaperone; IBA:GO_Central.
DR GO; GO:0045333; P:cellular respiration; ISO:RGD.
DR GO; GO:0034551; P:mitochondrial respiratory chain complex III assembly; ISO:RGD.
DR CDD; cd20267; Complex1_LYR_LYRM7; 1.
DR InterPro; IPR008011; Complex1_LYR_dom.
DR InterPro; IPR045298; Complex1_LYR_LYRM7.
DR Pfam; PF05347; Complex1_LYR; 1.
PE 3: Inferred from homology;
KW Chaperone; Mitochondrion; Phosphoprotein; Reference proteome.
FT CHAIN 1..104
FT /note="Complex III assembly factor LYRM7"
FT /id="PRO_0000370340"
FT MOD_RES 60
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q5U5X0"
SQ SEQUENCE 104 AA; 12030 MW; BCD9488955855103 CRC64;
MGQPAKVLQL FKTLHRTRQQ VFKNDKRALE AARVKINEEF KKHKNETSPE KIKEMLKIGS
DVELLLRTSV IQGIHTDHDT LQLVPRKDLL TENVPYCDAP TQKL