ID   LYRM7_TETNG             Reviewed;         104 AA.
AC   Q4SQJ2;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2005, sequence version 1.
DT   25-MAY-2022, entry version 50.
DE   RecName: Full=Complex III assembly factor LYRM7;
DE   AltName: Full=LYR motif-containing protein 7;
GN   Name=lyrm7; Synonyms=MZM1L; ORFNames=GSTENG00014346001;
OS   Tetraodon nigroviridis (Spotted green pufferfish) (Chelonodon
OS   nigroviridis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Tetraodon.
OX   NCBI_TaxID=99883;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15496914; DOI=10.1038/nature03025;
RA   Jaillon O., Aury J.-M., Brunet F., Petit J.-L., Stange-Thomann N.,
RA   Mauceli E., Bouneau L., Fischer C., Ozouf-Costaz C., Bernot A., Nicaud S.,
RA   Jaffe D., Fisher S., Lutfalla G., Dossat C., Segurens B., Dasilva C.,
RA   Salanoubat M., Levy M., Boudet N., Castellano S., Anthouard V., Jubin C.,
RA   Castelli V., Katinka M., Vacherie B., Biemont C., Skalli Z., Cattolico L.,
RA   Poulain J., De Berardinis V., Cruaud C., Duprat S., Brottier P.,
RA   Coutanceau J.-P., Gouzy J., Parra G., Lardier G., Chapple C.,
RA   McKernan K.J., McEwan P., Bosak S., Kellis M., Volff J.-N., Guigo R.,
RA   Zody M.C., Mesirov J., Lindblad-Toh K., Birren B., Nusbaum C., Kahn D.,
RA   Robinson-Rechavi M., Laudet V., Schachter V., Quetier F., Saurin W.,
RA   Scarpelli C., Wincker P., Lander E.S., Weissenbach J., Roest Crollius H.;
RT   "Genome duplication in the teleost fish Tetraodon nigroviridis reveals the
RT   early vertebrate proto-karyotype.";
RL   Nature 431:946-957(2004).
CC   -!- FUNCTION: Assembly factor required for Rieske Fe-S protein UQCRFS1
CC       incorporation into the cytochrome b-c1 (CIII) complex. Functions as a
CC       chaperone, binding to this subunit within the mitochondrial matrix and
CC       stabilizing it prior to its translocation and insertion into the late
CC       CIII dimeric intermediate within the mitochondrial inner membrane (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Interacts with UQCRFS1. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion matrix {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the complex I LYR family. {ECO:0000305}.
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DR   EMBL; CAAE01014532; CAF97090.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q4SQJ2; -.
DR   SMR; Q4SQJ2; -.
DR   STRING; 99883.ENSTNIP00000010283; -.
DR   Ensembl; ENSTNIT00000010464; ENSTNIP00000010283; ENSTNIG00000007474.
DR   KEGG; tng:GSTEN00014346G001; -.
DR   GeneTree; ENSGT00390000017923; -.
DR   HOGENOM; CLU_147114_1_1_1; -.
DR   InParanoid; Q4SQJ2; -.
DR   OMA; QNRNETN; -.
DR   TreeFam; TF324418; -.
DR   Proteomes; UP000007303; Unassembled WGS sequence.
DR   GO; GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
DR   GO; GO:0034551; P:mitochondrial respiratory chain complex III assembly; IEA:InterPro.
DR   CDD; cd20267; Complex1_LYR_LYRM7; 1.
DR   InterPro; IPR008011; Complex1_LYR_dom.
DR   InterPro; IPR045298; Complex1_LYR_LYRM7.
DR   Pfam; PF05347; Complex1_LYR; 1.
PE   3: Inferred from homology;
KW   Chaperone; Mitochondrion; Reference proteome.
FT   CHAIN           1..104
FT                   /note="Complex III assembly factor LYRM7"
FT                   /id="PRO_0000370342"
SQ   SEQUENCE   104 AA;  12284 MW;  F68633C3ADDC50BF CRC64;
     MGTRLKVLRV FKQLQRTRMD VFKDDDIALK AARLKINEEF RKNRNETSEE NINEMIKLGS
     NVETVLRESV LQMEHVGEDK LLLRPRKSLL LENVPYCDEP RKKS