LYRM7_XENTR
ID LYRM7_XENTR Reviewed; 104 AA.
AC A0JPA6;
DT 14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT 12-DEC-2006, sequence version 1.
DT 03-AUG-2022, entry version 54.
DE RecName: Full=Complex III assembly factor LYRM7;
DE AltName: Full=LYR motif-containing protein 7;
GN Name=lyrm7; Synonyms=MZM1L;
OS Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX NCBI_TaxID=8364;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Testis;
RG NIH - Xenopus Gene Collection (XGC) project;
RL Submitted (NOV-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Assembly factor required for Rieske Fe-S protein UQCRFS1
CC incorporation into the cytochrome b-c1 (CIII) complex. Functions as a
CC chaperone, binding to this subunit within the mitochondrial matrix and
CC stabilizing it prior to its translocation and insertion into the late
CC CIII dimeric intermediate within the mitochondrial inner membrane (By
CC similarity). {ECO:0000250}.
CC -!- SUBUNIT: Interacts with UQCRFS1. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion matrix {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the complex I LYR family. {ECO:0000305}.
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DR EMBL; BC127331; AAI27332.1; -; mRNA.
DR RefSeq; NP_001096231.1; NM_001102761.1.
DR AlphaFoldDB; A0JPA6; -.
DR SMR; A0JPA6; -.
DR STRING; 8364.ENSXETP00000058977; -.
DR PaxDb; A0JPA6; -.
DR DNASU; 100124785; -.
DR Ensembl; ENSXETT00000063860; ENSXETP00000058977; ENSXETG00000030784.
DR GeneID; 100124785; -.
DR KEGG; xtr:100124785; -.
DR CTD; 90624; -.
DR Xenbase; XB-GENE-963575; lyrm7.
DR eggNOG; ENOG502S5FU; Eukaryota.
DR HOGENOM; CLU_147114_1_1_1; -.
DR InParanoid; A0JPA6; -.
DR OMA; QNRNETN; -.
DR OrthoDB; 1585902at2759; -.
DR PhylomeDB; A0JPA6; -.
DR TreeFam; TF324418; -.
DR Proteomes; UP000008143; Chromosome 1.
DR Proteomes; UP000790000; Unplaced.
DR Bgee; ENSXETG00000030784; Expressed in testis and 13 other tissues.
DR GO; GO:0005759; C:mitochondrial matrix; IBA:GO_Central.
DR GO; GO:0044183; F:protein folding chaperone; IBA:GO_Central.
DR GO; GO:0045333; P:cellular respiration; IBA:GO_Central.
DR GO; GO:0034551; P:mitochondrial respiratory chain complex III assembly; IBA:GO_Central.
DR CDD; cd20267; Complex1_LYR_LYRM7; 1.
DR InterPro; IPR008011; Complex1_LYR_dom.
DR InterPro; IPR045298; Complex1_LYR_LYRM7.
DR Pfam; PF05347; Complex1_LYR; 1.
PE 3: Inferred from homology;
KW Chaperone; Mitochondrion; Reference proteome.
FT CHAIN 1..104
FT /note="Complex III assembly factor LYRM7"
FT /id="PRO_0000370344"
SQ SEQUENCE 104 AA; 12018 MW; 03FE6B7AB15F43E2 CRC64;
MDSRMKVLKL FKTLHRTRQC VFQNDCRALE AARRRINEEF KKNKSECSPA KISELLKFGT
DVEIVLRTSV VQGIHTDSNK LVLQARKDLL LDNIPFCDAP EKQT