LYSM1_MOUSE
ID LYSM1_MOUSE Reviewed; 226 AA.
AC Q9D0E3;
DT 05-SEP-2006, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 03-AUG-2022, entry version 135.
DE RecName: Full=LysM and putative peptidoglycan-binding domain-containing protein 1;
GN Name=Lysmd1;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J, and NOD; TISSUE=Dendritic cell, Embryo, and Ovary;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Fetal brain, and Retina;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
RN [3]
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-99 AND SER-193, AND
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC TISSUE=Brain, Brown adipose tissue, Heart, Kidney, Liver, Lung, Pancreas,
RC Spleen, and Testis;
RX PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL Cell 143:1174-1189(2010).
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DR EMBL; AK011517; BAB27671.1; -; mRNA.
DR EMBL; AK054348; BAC35742.1; -; mRNA.
DR EMBL; AK154180; BAE32423.1; -; mRNA.
DR EMBL; BC024838; AAH24838.1; -; mRNA.
DR EMBL; BC100548; AAI00549.1; -; mRNA.
DR CCDS; CCDS17602.1; -.
DR RefSeq; NP_694761.1; NM_153121.2.
DR AlphaFoldDB; Q9D0E3; -.
DR SMR; Q9D0E3; -.
DR BioGRID; 229961; 3.
DR STRING; 10090.ENSMUSP00000067811; -.
DR iPTMnet; Q9D0E3; -.
DR PhosphoSitePlus; Q9D0E3; -.
DR MaxQB; Q9D0E3; -.
DR PaxDb; Q9D0E3; -.
DR PRIDE; Q9D0E3; -.
DR ProteomicsDB; 292133; -.
DR Antibodypedia; 34054; 117 antibodies from 18 providers.
DR Ensembl; ENSMUST00000066386; ENSMUSP00000067811; ENSMUSG00000053769.
DR GeneID; 217779; -.
DR KEGG; mmu:217779; -.
DR UCSC; uc008qie.2; mouse.
DR CTD; 388695; -.
DR MGI; MGI:1919409; Lysmd1.
DR VEuPathDB; HostDB:ENSMUSG00000053769; -.
DR eggNOG; ENOG502RZER; Eukaryota.
DR GeneTree; ENSGT00940000160002; -.
DR HOGENOM; CLU_079453_0_0_1; -.
DR InParanoid; Q9D0E3; -.
DR OMA; WPHSAER; -.
DR OrthoDB; 1553362at2759; -.
DR PhylomeDB; Q9D0E3; -.
DR TreeFam; TF318444; -.
DR BioGRID-ORCS; 217779; 5 hits in 40 CRISPR screens.
DR ChiTaRS; Lysmd1; mouse.
DR PRO; PR:Q9D0E3; -.
DR Proteomes; UP000000589; Chromosome 3.
DR RNAct; Q9D0E3; protein.
DR Bgee; ENSMUSG00000053769; Expressed in bone marrow and 59 other tissues.
DR ExpressionAtlas; Q9D0E3; baseline and differential.
DR Genevisible; Q9D0E3; MM.
DR GO; GO:0005654; C:nucleoplasm; ISO:MGI.
DR CDD; cd00118; LysM; 1.
DR Gene3D; 3.10.350.10; -; 1.
DR InterPro; IPR045030; LYSM1-4.
DR InterPro; IPR018392; LysM_dom.
DR InterPro; IPR036779; LysM_dom_sf.
DR PANTHER; PTHR20932; PTHR20932; 1.
DR Pfam; PF01476; LysM; 1.
DR SMART; SM00257; LysM; 1.
DR SUPFAM; SSF54106; SSF54106; 1.
DR PROSITE; PS51782; LYSM; 1.
PE 1: Evidence at protein level;
KW Phosphoprotein; Reference proteome.
FT CHAIN 1..226
FT /note="LysM and putative peptidoglycan-binding domain-
FT containing protein 1"
FT /id="PRO_0000247998"
FT DOMAIN 40..84
FT /note="LysM"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01118"
FT REGION 95..156
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 170..226
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 122..156
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 23
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q96S90"
FT MOD_RES 33
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q96S90"
FT MOD_RES 99
FT /note="Phosphoserine"
FT /evidence="ECO:0007744|PubMed:21183079"
FT MOD_RES 165
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q96S90"
FT MOD_RES 180
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q5HZA4"
FT MOD_RES 193
FT /note="Phosphoserine"
FT /evidence="ECO:0007744|PubMed:21183079"
FT MOD_RES 211
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q96S90"
SQ SEQUENCE 226 AA; 24814 MW; B378600A2F754B0F CRC64;
MASPSRQPPL GGSGLLHGSR ARSYGSLVQS SCSPVRERRL EHQLEPGDTL AGLALKYGVT
MEQIKRTNRL YTNDSIFLKK TLYIPILSEP RDLFNGLDSE EENDGEEEVR PSKDEIGSSS
GRRKNRGSGS GRPNGTGLPP HQETSTPSHD LSASDFLKKL DSQISLSKKA AAQKLRKGES
GVPEEDTGLY PSSPRMQQRA VLGPVPLTRT SRTQTLRDQE DEIFKL
