ID   LYSM3_RAT               Reviewed;         300 AA.
AC   Q5M836;
DT   05-SEP-2006, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-2005, sequence version 1.
DT   03-AUG-2022, entry version 103.
DE   RecName: Full=LysM and putative peptidoglycan-binding domain-containing protein 3;
GN   Name=Lysmd3;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Spleen;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- FUNCTION: Essential for Golgi structural integrity.
CC       {ECO:0000250|UniProtKB:Q7Z3D4}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:Q7Z3D4};
CC       Single-pass membrane protein {ECO:0000255}. Golgi apparatus
CC       {ECO:0000250|UniProtKB:Q7Z3D4}.
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DR   EMBL; BC088262; AAH88262.1; -; mRNA.
DR   RefSeq; NP_001009698.1; NM_001009698.1.
DR   AlphaFoldDB; Q5M836; -.
DR   SMR; Q5M836; -.
DR   STRING; 10116.ENSRNOP00000021818; -.
DR   GlyGen; Q5M836; 3 sites.
DR   PaxDb; Q5M836; -.
DR   Ensembl; ENSRNOT00000021818; ENSRNOP00000021818; ENSRNOG00000016298.
DR   GeneID; 315923; -.
DR   KEGG; rno:315923; -.
DR   UCSC; RGD:1308805; rat.
DR   CTD; 116068; -.
DR   RGD; 1308805; Lysmd3.
DR   eggNOG; KOG2850; Eukaryota.
DR   GeneTree; ENSGT00940000158711; -.
DR   HOGENOM; CLU_070676_0_0_1; -.
DR   InParanoid; Q5M836; -.
DR   OMA; RRKDPYY; -.
DR   OrthoDB; 1180847at2759; -.
DR   PhylomeDB; Q5M836; -.
DR   TreeFam; TF326271; -.
DR   PRO; PR:Q5M836; -.
DR   Proteomes; UP000002494; Chromosome 2.
DR   Bgee; ENSRNOG00000016298; Expressed in jejunum and 19 other tissues.
DR   Genevisible; Q5M836; RN.
DR   GO; GO:0005794; C:Golgi apparatus; ISS:UniProtKB.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; ISS:UniProtKB.
DR   GO; GO:0007030; P:Golgi organization; ISS:UniProtKB.
DR   CDD; cd00118; LysM; 1.
DR   Gene3D; 3.10.350.10; -; 1.
DR   InterPro; IPR045030; LYSM1-4.
DR   InterPro; IPR018392; LysM_dom.
DR   InterPro; IPR036779; LysM_dom_sf.
DR   PANTHER; PTHR20932; PTHR20932; 1.
DR   Pfam; PF01476; LysM; 1.
DR   SMART; SM00257; LysM; 1.
DR   PROSITE; PS51782; LYSM; 1.
PE   2: Evidence at transcript level;
KW   Cell membrane; Glycoprotein; Golgi apparatus; Membrane; Phosphoprotein;
KW   Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..300
FT                   /note="LysM and putative peptidoglycan-binding domain-
FT                   containing protein 3"
FT                   /id="PRO_0000248009"
FT   TOPO_DOM        1..216
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        217..237
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        238..300
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   DOMAIN          65..109
FT                   /note="LysM"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01118"
FT   REGION          136..157
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          253..300
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        142..157
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        286..300
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         55
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q7Z3D4"
FT   CARBOHYD        7
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        26
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        199
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   300 AA;  33702 MW;  FF256D863944D6DC CRC64;
     MAGRNQNRTA SLAGIQASGH VHTFGNCTDN DMLEEDAEVY ELRSRGKEKV RRSTSRDRLD
     DIVILTKDIQ EGDTLNAVAL QYCCTVADIK RVNNLISDQD FFALRSIKIP VKRFSSLTET
     LHPLKGRQVL HPPPVPYFQE QDTVPANDSP SSSESAGSFL KEVDRDIEQI VKCTDTKKEN
     LNEVVSALTA QQVRFEPDNK SVHRKDPYYG ADWGMGWWTA VVIMLIVGII TPVFYLLYYE
     ILAKVDVSHH STVDSSHLHP GLTPPSHHRE MGNAIGPTKG IPVGQQDDHR LYRQDPQARD