ID   LYSO_HAEIN              Reviewed;         195 AA.
AC   P44201;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 1.
DT   03-AUG-2022, entry version 114.
DE   RecName: Full=Putative lysine exporter {ECO:0000250|UniProtKB:P75826};
GN   OrderedLocusNames=HI_1452;
OS   Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Haemophilus.
OX   NCBI_TaxID=71421;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51907 / DSM 11121 / KW20 / Rd;
RX   PubMed=7542800; DOI=10.1126/science.7542800;
RA   Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F.,
RA   Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M.,
RA   McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D.,
RA   Scott J.D., Shirley R., Liu L.-I., Glodek A., Kelley J.M., Weidman J.F.,
RA   Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R.,
RA   Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D.,
RA   Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A.,
RA   Small K.V., Fraser C.M., Smith H.O., Venter J.C.;
RT   "Whole-genome random sequencing and assembly of Haemophilus influenzae
RT   Rd.";
RL   Science 269:496-512(1995).
CC   -!- FUNCTION: Mediates export of lysine. {ECO:0000250|UniProtKB:P75826}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305}; Multi-pass
CC       membrane protein {ECO:0000255}.
CC   -!- SIMILARITY: Belongs to the LysO family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; L42023; AAC23105.1; -; Genomic_DNA.
DR   PIR; D64030; D64030.
DR   RefSeq; NP_439603.1; NC_000907.1.
DR   RefSeq; WP_005693915.1; NC_000907.1.
DR   AlphaFoldDB; P44201; -.
DR   EnsemblBacteria; AAC23105; AAC23105; HI_1452.
DR   KEGG; hin:HI_1452; -.
DR   PATRIC; fig|71421.8.peg.1513; -.
DR   eggNOG; COG2431; Bacteria.
DR   HOGENOM; CLU_078428_1_0_6; -.
DR   OMA; WLHHASA; -.
DR   PhylomeDB; P44201; -.
DR   BioCyc; HINF71421:G1GJ1-1477-MON; -.
DR   Proteomes; UP000000579; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   GO; GO:0015661; F:L-lysine efflux transmembrane transporter activity; IBA:GO_Central.
DR   InterPro; IPR005642; LysO.
DR   PANTHER; PTHR35804; PTHR35804; 1.
DR   Pfam; PF03956; Lys_export; 1.
PE   3: Inferred from homology;
KW   Amino-acid transport; Cell inner membrane; Cell membrane; Membrane;
KW   Reference proteome; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..195
FT                   /note="Putative lysine exporter"
FT                   /id="PRO_0000168738"
FT   TRANSMEM        4..24
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        30..50
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        61..81
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        86..106
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        117..137
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        170..190
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   195 AA;  21241 MW;  56155768F992102F CRC64;
     MEELLSAVII GIVLGWLCKD WLHFPNGSNL YVLITLIFFV GIQLRNNGIS LKEVLLNKQG
     LMMGAIFTLS SLIGGVISAF FLSMPITQGL AFSSGFGWYS LSSVVLTNAW GPMQGSIAFF
     NDLSREILSL FLIPLFMQHY RSTAIEITGA TALDCTLPII QKSGGIEVTP IAISFGMVTN
     LLPPLLLVFF SSFPI