ID   LYS_BPJP3               Reviewed;          63 AA.
AC   P34702;
DT   01-FEB-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1994, sequence version 1.
DT   03-AUG-2022, entry version 37.
DE   RecName: Full=Lysis protein;
OS   Enterobacteria phage JP34 (Bacteriophage JP34).
OC   Viruses; Riboviria; Orthornavirae; Lenarviricota; Leviviricetes;
OC   Levivirales; Leviviridae; Levivirus.
OX   NCBI_TaxID=12019;
OH   NCBI_TaxID=562; Escherichia coli.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX   PubMed=2718383; DOI=10.1016/0042-6822(89)90371-1;
RA   Adhin M.R., Hirashima A., van Duin J.;
RT   "Nucleotide sequence from the ssRNA bacteriophage JP34 resolves the
RT   discrepancy between serological and biophysical classification.";
RL   Virology 170:238-242(1989).
CC   -!- FUNCTION: Induces the formation of specific membrane adhesion sites
CC       between the inner and outer membranes, apparently leading to host cell
CC       lysis. Lysis may be performed via activation of host murein hydrolases.
CC       {ECO:0000250|UniProtKB:P03609}.
CC   -!- SUBCELLULAR LOCATION: Host cell inner membrane
CC       {ECO:0000250|UniProtKB:P03609}; Single-pass membrane protein
CC       {ECO:0000255}. Host cell outer membrane {ECO:0000250|UniProtKB:P03609};
CC       Single-pass membrane protein {ECO:0000255}.
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DR   EMBL; J04343; AAA72211.1; -; Genomic_RNA.
DR   PIR; B46324; B46324.
DR   SMR; P34702; -.
DR   GO; GO:0020002; C:host cell plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0019835; P:cytolysis; IEA:UniProtKB-KW.
DR   InterPro; IPR022599; Phage_MS2_lysis.
DR   Pfam; PF11125; DUF2830; 1.
PE   3: Inferred from homology;
KW   Cytolysis; Host cell inner membrane; Host cell lysis by virus;
KW   Host cell membrane; Host cell outer membrane; Host membrane; Membrane;
KW   Transmembrane; Transmembrane helix; Viral release from host cell.
FT   CHAIN           1..63
FT                   /note="Lysis protein"
FT                   /id="PRO_0000164863"
FT   TRANSMEM        21..43
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   63 AA;  7335 MW;  9173853CD85CB206 CRC64;
     MGLKAKHKEN LCSDSQRSKR LYVWIALAIV LSDFTSIFSH WIWGLLILIL RTLMDLPTFV
     MNV