ID   LYTA_BACSU              Reviewed;         102 AA.
AC   Q02112;
DT   01-JUL-1993, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-1993, sequence version 1.
DT   03-AUG-2022, entry version 103.
DE   RecName: Full=Membrane-bound protein LytA;
DE   Flags: Precursor;
GN   Name=lytA; Synonyms=lppX; OrderedLocusNames=BSU35640;
OS   Bacillus subtilis (strain 168).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=224308;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND REPRESSION BY LYTR.
RC   STRAIN=168;
RX   PubMed=1357079; DOI=10.1099/00221287-138-9-1949;
RA   Lazarevic V., Margot P., Soldo B., Karamata D.;
RT   "Sequencing and analysis of the Bacillus subtilis lytRABC divergon: a
RT   regulatory unit encompassing the structural genes of the N-acetylmuramoyl-
RT   L-alanine amidase and its modifier.";
RL   J. Gen. Microbiol. 138:1949-1961(1992).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=1356138; DOI=10.1099/00221287-138-6-1067;
RA   Kuroda A., Rashid H.M., Sekiguchi J.;
RT   "Molecular cloning and sequencing of the upstream region of the major
RT   Bacillus subtilis autolysin gene: a modifier protein exhibiting sequence
RT   homology to the major autolysin and the spoIID product.";
RL   J. Gen. Microbiol. 138:1067-1076(1992).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9384377; DOI=10.1038/36786;
RA   Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA   Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA   Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA   Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA   Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA   Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA   Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA   Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA   Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA   Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA   Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA   Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA   Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA   Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA   Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA   Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA   Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA   Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA   Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA   Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA   Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA   Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA   Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA   Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA   Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA   Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA   Yoshikawa H., Danchin A.;
RT   "The complete genome sequence of the Gram-positive bacterium Bacillus
RT   subtilis.";
RL   Nature 390:249-256(1997).
CC   -!- FUNCTION: Possible role in the secretion of LytB and LytC.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Lipid-anchor
CC       {ECO:0000305}.
CC   -!- INDUCTION: Repressed by LytR. {ECO:0000269|PubMed:1357079}.
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DR   EMBL; M87645; AAA22579.1; -; Genomic_DNA.
DR   EMBL; D10388; BAA01223.1; -; Genomic_DNA.
DR   EMBL; AL009126; CAB15581.1; -; Genomic_DNA.
DR   PIR; B47679; B47679.
DR   RefSeq; NP_391444.1; NC_000964.3.
DR   RefSeq; WP_003242772.1; NZ_JNCM01000033.1.
DR   AlphaFoldDB; Q02112; -.
DR   STRING; 224308.BSU35640; -.
DR   PaxDb; Q02112; -.
DR   PRIDE; Q02112; -.
DR   EnsemblBacteria; CAB15581; CAB15581; BSU_35640.
DR   GeneID; 936784; -.
DR   KEGG; bsu:BSU35640; -.
DR   PATRIC; fig|224308.179.peg.3855; -.
DR   OMA; VEISYFI; -.
DR   BioCyc; BSUB:BSU35640-MON; -.
DR   Proteomes; UP000001570; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   2: Evidence at transcript level;
KW   Cell membrane; Lipoprotein; Membrane; Palmitate; Reference proteome;
KW   Signal.
FT   SIGNAL          1..16
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   CHAIN           17..102
FT                   /note="Membrane-bound protein LytA"
FT                   /id="PRO_0000018180"
FT   LIPID           17
FT                   /note="N-palmitoyl cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   LIPID           17
FT                   /note="S-diacylglycerol cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
SQ   SEQUENCE   102 AA;  11228 MW;  4BE28B0AA3F9A9FC CRC64;
     MKKFIALLFF ILLLSGCGVN SQKSQGEDVS PDSNIETKEG TYVGLADTHT IEVTVDNEPV
     SLDITEESTS DLDKFNSGDK VTITYEKNDE GQLLLKDIER AN