ID   LYTT_ENTFA              Reviewed;         242 AA.
AC   Q82Z76;
DT   15-MAR-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   03-AUG-2022, entry version 107.
DE   RecName: Full=Sensory transduction protein LytT;
GN   Name=lytT; OrderedLocusNames=EF_3196;
OS   Enterococcus faecalis (strain ATCC 700802 / V583).
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
OC   Enterococcus.
OX   NCBI_TaxID=226185;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700802 / V583;
RX   PubMed=12663927; DOI=10.1126/science.1080613;
RA   Paulsen I.T., Banerjei L., Myers G.S.A., Nelson K.E., Seshadri R.,
RA   Read T.D., Fouts D.E., Eisen J.A., Gill S.R., Heidelberg J.F., Tettelin H.,
RA   Dodson R.J., Umayam L.A., Brinkac L.M., Beanan M.J., Daugherty S.C.,
RA   DeBoy R.T., Durkin S.A., Kolonay J.F., Madupu R., Nelson W.C.,
RA   Vamathevan J.J., Tran B., Upton J., Hansen T., Shetty J., Khouri H.M.,
RA   Utterback T.R., Radune D., Ketchum K.A., Dougherty B.A., Fraser C.M.;
RT   "Role of mobile DNA in the evolution of vancomycin-resistant Enterococcus
RT   faecalis.";
RL   Science 299:2071-2074(2003).
CC   -!- FUNCTION: Member of the two-component regulatory system LytS/LytT that
CC       probably regulates genes involved in cell wall metabolism.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
CC   -!- PTM: Phosphorylated by LytS. {ECO:0000305}.
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DR   EMBL; AE016830; AAO82868.1; -; Genomic_DNA.
DR   RefSeq; NP_816798.1; NC_004668.1.
DR   RefSeq; WP_002367483.1; NZ_KE136524.1.
DR   AlphaFoldDB; Q82Z76; -.
DR   SMR; Q82Z76; -.
DR   STRING; 226185.EF_3196; -.
DR   EnsemblBacteria; AAO82868; AAO82868; EF_3196.
DR   KEGG; efa:EF3196; -.
DR   PATRIC; fig|226185.45.peg.384; -.
DR   eggNOG; COG3279; Bacteria.
DR   HOGENOM; CLU_000445_14_1_9; -.
DR   OMA; DIHMPDF; -.
DR   Proteomes; UP000001415; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0000160; P:phosphorelay signal transduction system; IEA:UniProtKB-KW.
DR   InterPro; IPR011006; CheY-like_superfamily.
DR   InterPro; IPR007492; LytTR_DNA-bd_dom.
DR   InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR   InterPro; IPR039420; WalR-like.
DR   PANTHER; PTHR48111; PTHR48111; 1.
DR   Pfam; PF04397; LytTR; 1.
DR   Pfam; PF00072; Response_reg; 1.
DR   SMART; SM00850; LytTR; 1.
DR   SMART; SM00448; REC; 1.
DR   SUPFAM; SSF52172; SSF52172; 1.
DR   PROSITE; PS50930; HTH_LYTTR; 1.
DR   PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE   4: Predicted;
KW   Cytoplasm; DNA-binding; Phosphoprotein; Reference proteome; Transcription;
KW   Transcription regulation; Two-component regulatory system.
FT   CHAIN           1..242
FT                   /note="Sensory transduction protein LytT"
FT                   /id="PRO_0000081124"
FT   DOMAIN          2..116
FT                   /note="Response regulatory"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00169"
FT   DOMAIN          137..241
FT                   /note="HTH LytTR-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00112"
SQ   SEQUENCE   242 AA;  27551 MW;  AA1083617E831571 CRC64;
     MHVLIVDDEP LAREELSYLV SQHPQVTSVA EADSVAEAME EMMDQKPDLL FLDIHLTDES
     GFDLAEKLTH LKKAPYLVFA TAYDQYALKA FQVNAKDYIL KPFEEEKITQ VIEKASKEMG
     QAVPENTAEK GPKSEAIPIQ GEDRIYLVAP EDIYLVSVEE RQLSIFVDQQ VYKMTGTLNS
     IEQKLPATLF IKTHRSFILN RTKIQEIQPW FNNTLQVILT NGSKVPVSRS YVKEFKEKLG
     LS