M1249_ASFM2
ID M1249_ASFM2 Reviewed; 1249 AA.
AC P0CAB4;
DT 05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT 05-MAY-2009, sequence version 1.
DT 03-AUG-2022, entry version 21.
DE RecName: Full=Minor capsid protein M1249L {ECO:0000250|UniProtKB:Q65152};
DE Short=pM1249L;
GN OrderedLocusNames=Mal-068;
OS African swine fever virus (isolate Tick/Malawi/Lil 20-1/1983) (ASFV).
OC Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC Asfuvirales; Asfarviridae; Asfivirus.
OX NCBI_TaxID=10500;
OH NCBI_TaxID=6937; Ornithodoros (relapsing fever ticks).
OH NCBI_TaxID=85517; Phacochoerus aethiopicus (Warthog).
OH NCBI_TaxID=41426; Phacochoerus africanus (Warthog).
OH NCBI_TaxID=273792; Potamochoerus larvatus (Bushpig).
OH NCBI_TaxID=9823; Sus scrofa (Pig).
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Kutish G.F., Rock D.L.;
RT "African swine fever virus genomes.";
RL Submitted (MAR-2003) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Together with the penton and the other minor capsid proteins
CC (p17, p49), forms a complicated network immediately below the outer
CC capsid shell, stabilizing the whole capsid.
CC {ECO:0000250|UniProtKB:Q65152}.
CC -!- SUBUNIT: Interacts with the minor capsid protein p17 and with the hexon
CC capsid protein p72 capsomers; these interactions form a rigid zipper
CC structure that stabilizes the capsomers.
CC {ECO:0000250|UniProtKB:Q65152}.
CC -!- SUBCELLULAR LOCATION: Virion {ECO:0000250|UniProtKB:Q65152}.
CC -!- INDUCTION: Expressed in the late phase of the viral replicative cycle.
CC {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the asfivirus M1249L family. {ECO:0000305}.
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DR EMBL; AY261361; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR SMR; P0CAB4; -.
DR PRIDE; P0CAB4; -.
DR Proteomes; UP000000860; Genome.
PE 3: Inferred from homology;
KW Late protein; Virion.
FT CHAIN 1..1249
FT /note="Minor capsid protein M1249L"
FT /id="PRO_0000373611"
SQ SEQUENCE 1249 AA; 144509 MW; 4204DF16B7C39577 CRC64;
MEEVITIAQI VHRGTDILSL NNEEIEALVD EIRSTLKGSN DIKNIRLIDF LFTLKDFVNH
VRAEQSKLPN LSMPMEAYIR QLLVNPDVIP IVSEKKKELR VRPSTRKEIF LINGTHLAVP
AEVPIEIYGL KLRLKTFSPQ CFMRMAEIGS FLPETLGYVA SGANLTNFIR VFMKCVDQET
WKKNGEGIVV TTKENIIQFT HQYIELYKFL RSGGHSWLIN RLAEEMVHRK LDREDQGSHI
SSVIETEEIE PEENIKRVIF FLKELSTMYS VFPVFTSGYM PLLYDLYRAG YLEVLWNPVE
QKFLQHAEQR EKEQMILQQV DMKLTEVTTQ ARQYFKIMEE KIGRVQSDAI REILTMEGKV
DDPNSILQEV IKACGKQEAE LITTEYLNIK KQWELQEKNA CAHLKLVKQL RSGLQYAESL
KVLESIRVLY KEKNNTTNWN LCKACGFKLL CPHVDMLIQL QAAEASYDTM RTKLMKFSGI
NKEKENNQGL IYSYFCKICG EELAHFVQED RTADVGVIGD LNSKLRIFIW QETMKACTFI
HFGKLVDVKQ FANIAVNVCL PLIYNIENIK KEEDYDPLTQ LYAVIYIYAY ILNLIYSSQK
NKEFLTITIH GMKADSSLNA YVTFLLEKMT QQYSGIINQL SEITDQWIAN NFREAFKKII
HQNGLQGLSV QDDTKVLLTE ILLDPLYDYA ATVARIDGSI PMHKPQTPKE AEYEFKTVIG
RTPTELLSQK EFYDKIYTFK YRPDFTQLAR LNDIYFQEES LRVWWGGRDE EKISTLIYLK
AYELFLKYLQ NAPNFNLELA EFKKYENAYG EQRALLAQQG FYNIFDPNTG RADQRTRLFE
YKKLPISTLY DEKGLPHKWT IYVYKAIDSS QKPAEIEVSR KDVIKKIDNH YALADLRCSV
CHVLQHEVGQ LNIKKVQTAL KASLEFNTFY AFYESRCPKG GLHDFQDKKC VKCGLFTYII
YDHLSQPELV HDYYNNYKDQ YDKEKMSIHS IQMKKDIAVP SAETQPEPQQ EPWTFDYGKI
IKTAKILDIS PAVIEAIGAM EGRSYADIKE GQGAPPPPTS MDDPRLMAVD SAVRIFLYNY
NCLRHISTFN KPPMYIERLV KHLSYEEKED LEKVLPNVVN EYHTTFKQLR VTDPASALLY
SIEFLCISFL TLYEIKEPSW VVNIIREFAL TELNTIIQSE KLLSKPGAFN FMIFGEDFVC
SGEDSSMDDI SAYSSPGLFG EDIIDQLDDP FSIEDVDISL DVLDNLAPQ